Cancer Genome & Epigenome Integrity
The University of Florida Health Cancer Center Cancer Genome and Epigenome Integrity (CGEI) research program is centered around gene expression, metabolism and cell proliferation.
- Connect DNA damage signaling with replication fork repair and restart
- Dissect the role of chromosomal instability in oncogenesis
- Define epigenetic mechanisms of treatment resistance and design methods to overcome barriers
Robert A. Hromas, M.D., FACP, graduated from medical school at the University of Texas at Houston, where he was named an Outstanding Student in Internal Medicine. Dr. Hromas trained in blood cancers at the Fred Hutchinson Cancer Research Center with the Nobel Laureate Dr. Don Thomas and then joined the faculty at Indiana University Medical Center for 13 years before going to the University of New Mexico.
He is a leader in translating research into the discovery of new cancer drugs. A professor and chief of hematology-oncology at UNM, Dr. Hromas also was the deputy director of the UNM Cancer Center, the official cancer center of the state of New Mexico and one of only 66 National Cancer Institute-designated centers in the United States.
His background is in molecular genetics and DNA repair. He does drug design in silico, producing and screening cancer drug candidates through computer simulations. Dr. Hromas recently cloned and characterized several novel DNA repair proteins that play crucial roles in both chemotherapy resistance and in HIV integration. He has created new drugs that target these proteins and is testing them for effectiveness in treating cancers resistant to chemotherapy.
Dr. Hromas has held more than $8 million in cancer research grants and numerous national medical and scientific leadership positions. He has chaired grant review committees for the National Institutes of Health and for the American Cancer Society. He has served on the Lance Armstrong Foundation Scientific Board and has been elected to the American Society of Clinical Investigation and the Association of American Physicians. He has won multiple awards, including the Indiana University Board of Regents Teacher of the Year and the New Mexico People Caring Award.
|Baer, Charles F.||PhD||Assistant Professor||BIOLOGY||LIB ARTS / SCIENCES|
|Bungert, Jorg||PhD||Professor||BIOCHEM / MOLECULAR BIOL||MEDICINE|
|Concannon, Patrick||PhD||Director / Professor||GENETICS INSTITUTE||MEDICINE|
|Frost, Susan||PhD||Professor||BIOCHEM / MOLECULAR BIOL||MEDICINE|
|Guryanova, Olga||MD, PhD||Assistant Professor||PHARMACOLOGY / THERAPEUTICS||MEDICINE|
|Hromas, Robert||MD||Chair / Professor||MEDICINE CHAIRMAN||MEDICINE|
|Huang, Suming||PhD||Associate Professor||BIOCHEM / MOLECULAR BIOL||MEDICINE|
|Ishov, Alexander M.||PhD||Associate Professor||ANATOMY||MEDICINE|
|Kilberg, Michael S.||PhD||Professor||BIOCHEM / MOLECULAR BIOL||MEDICINE|
|Kladde, Michael P.||PhD||Associate Professor||BIOCHEMISTRY-GENERAL||MEDICINE|
|Lele, Tanmay P.||PhD||Associate Professor||CHEMICAL ENGINEERING||ENGINEERING|
|Li, Chenglong||PhD||Professor||MEDICINAL CHEMISTRY||PHARMACY|
|Liang, Faming||PhD||Professor||BIOSTATISTICS||PHHP-COM INTEGRATED PROGRAMS|
|Liao, Daiqing||PhD||Associate Professor||ANATOMY||MEDICINE|
|Licht, Jonathan D.||MD||Director / Professor||HEMATOLOGY/ONCOLOGY-ONCOL||MEDICINE|
|Michailidis, George||PhD||Director / Professor||INFORMATICS INSTITUTE||OFFICE OF RESEARCH|
|Terada, Naohiro||MD, PhD||Professor||PATHOLOGY||MEDICINE|
|Wu, Lizi||PhD||Associate Professor||MOLECULAR GENTCS / MICROBIO||MEDICINE|
|Xie, Mingyi||PhD||Asstistant Professor||BIOCHEM / MOLECULAR BIOL||MEDICINE|
|Zhou, Lei||BMed, PhD||Associate Professor||MOLECULAR GENTCS / MICROBIO||MEDICINE|