Cancer Therapeutics & Immuno-Oncology

 

SAVE THE DATE 

CTI program meetings will be held the 4th Monday of every month 

5:00 PM – 6:00 PM

Harrell Medical Education Building (map)

1104 Newell Dr., Gainesville, FL 32601

Contact: Natalie Roman | natalie.roman@ufl.edu

Mission

The mission of the University of Florida Health Cancer Center Cancer Theapeutics and Immuno-Oncology (CTI) research program is to develop novel and effective targeted therapeutics and cancer immunotherapies for the treatment of refractory malignancies.

Aims:

  • Conduct first-in-human immunotherapy clinical trials for refractory malignancies
  • Interrogate the role of host immune cells in tumor response and resistance to standard and experimental therapies
  • Advance novel small molecule inhibitors of cancer through a preclinical to clinical development pathway

Program Leader

Duane A. Mitchell, M.D., Ph.D. is Co-Director of the Preston A. Wells Jr. Center for Brain Tumor Therapy and Director of the UF Brain Tumor Immunotherapy Program. He is the Phyllis Kottler Friedman Professor in the Department of Neurosurgery and the State of Florida Endowed Cancer Research Chair at the University of Florida College of Medicine.

In 2013, Dr. Mitchell joined the University of Florida faculty and leads a comprehensive brain tumor program focused on translational research. He has considerable clinical and translational research experience having served as principal investigator on seven first-in-human protocols through FDA-approved clinical trials. The goal of these trials is to see improvements in patient outcomes using novel approaches that stimulate immune responses against malignant brain tumor cells in combination with current standard treatments. Dr. Mitchell’s research team will expand upon early successes observed in these personalized cancer treatment approaches, and offer unique clinical options at UF for adult and pediatric patients diagnosed with malignant brain tumors.

Dr. Mitchell currently serves as a chartered member of the NIH study section on Cancer Immunopathology and Immunotherapy, Chair of the NCI Pediatric Brain Tumor Consortium Immunotherapy Committee, member of the NCI Brain Malignancy Steering Committee Immunotherapy Working Group, and as gubernatorial appointee to the Florida Center for Brain Tumor Research Scientific Advisory Council. His work is supported by the Department of Defense, the National Cancer Institute, the National Institute of Neurologic Diseases and Stroke, and several private funding agencies.

Members

Member Name Degree Academic Title Department /Division College
Allegra, Carmen MD Division Chief / Professor HEMATOLOGY/ONCOLOGY MEDICINE
Bradley, Julie A. MD Assistant Professor RADIATION ONCOLOGY MEDICINE
Brown, Randy A. BS, MD Clinical Professor HEMATOLOGY/ONCOLOGY MEDICINE
Cabrera, Roniel MD, MS Associate Professor GASTROENTERLOGY-LIVER MEDICINE
Castellano, Ronald K. PhD Associate Professor CHEMISTRY-GENERAL LIB ARTS / SCIENCES
Close, Julia L. MD Clinical Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Cogle, Christopher R. MD Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
Dagan, Roi MD Clinical Assistant Professor RADIATION ONCOLOGY MEDICINE
Daily Weinstein, Karen DO Clinical Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Dang, Long H. MD, PhD Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
Dang, Nam H. MD, PhD Program Director / Professor HEMATOLOGY/ONCOLOGY MEDICINE
Fan, Z Hugh PhD Professor MECHANICAL / AEROSPACE ENG ENGINEERING
Flores, Catherine PhD Assistant Professor NEUROLOGICAL SURGERY MEDICINE
Fort, John MD Clinical Associate Professor PEDS-HEMATOLOGY MEDICINE
Friedman, William A. MD Chair / Professor NEUROLOGICAL SURGERY MEDICINE
George, Thomas J. BS, MD Program Director / Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
Ghivizzani, Steven C. PhD Program Director / Professor ORTHOPAEDICS / REHAB MEDICINE
Gibbs, C. Parker MD Chief & Professor ORTHOPAEDICS / REHAB MEDICINE
Golde, Todd E. MD, PhD Professor NEUROSCIENCE-GENERAL MEDICINE
Gopalan, Priya K. MD, PhD Clinical Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Gururangan, Sridharan FRCP Director / Professor NEUROLOGICAL SURGERY MEDICINE
Harrison, Jeffrey K. PhD Professor PHARMACOLOGY / THERAPEUTICS MEDICINE
Heldermon, Coy MD, PhD Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Henderson, Randal H. MD Clinical Professor RADIATION ONCOLOGY MEDICINE
Herzog, Roland W. PhD Professor PEDS-CELL / MOLEC THERP DIV MEDICINE
Hiemenz, John W. MD Clinical Professor HEMATOLOGY/ONCOLOGY MEDICINE
Hoppe, Bradford S. MD, MPH Associate Professor RADIATION ONCOLOGY MEDICINE
Hsu, Jack W. MD Clinical Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Indelicato, Daniel J. MD Associate Professor RADIATION ONCOLOGY MEDICINE
James, Margaret O. PhD, DSc Professor MEDICINAL CHEMISTRY PHARMACY
Jiang, Huabei PhD Professor BIOMEDICAL ENGINEERING ENGINEERING
Jones, Dennie V. MD Professor HEMATOLOGY/ONCOLOGY MEDICINE
Kaye, Frederic MD Professor HEMATOLOGY/ONCOLOGY MEDICINE
Lagmay, Joanne MD Program Director / Clinical Assistant Professor PEDS-HEMATOLOGY MEDICINE
Lamba, Jatinder K. PhD Associate Professor PHARMTHERAPY TRNSL RSCH PHARMACY
Law, Brian K. PhD Associate Professor PHARMACOLOGY / THERAPEUTICS MEDICINE
Li, Ying MD, PhD Clinical Professor PATHOLOGY MEDICINE
Luesch, Hendrik PhD Chair / Professor MEDICINAL CHEMISTRY PHARMACY
Markham, Merry J. MD Clinical Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
May, W. Stratford MD, PhD Program Director / Professor HEMATOLOGY/ONCOLOGY MEDICINE
Devidas, Meenakshi PhD Program Director / Research Professor BIOSTATISTICS PHHP-COM INTEGRATED PROGRAMS
Mendenhall, Nancy P. MD Associate Chair / Professor RADIATION ONCOLOGY MEDICINE
Mendenhall, William M. MD Professor RADIATION ONCOLOGY MEDICINE
Milner, Rowan J. BVSc, MMedVet Chair & Professor VETERINARY MEDICINE VETERINARY MED
Mitchell, Duane A. MD, PhD Associate Chair / Associate Professor NEUROLOGICAL SURGERY MEDICINE
Moreb, Jan S. MD Professor HEMATOLOGY/ONCOLOGY MEDICINE
Murad, Gregory J.A. MD Program Director / Clinical Associate Professor NEUROLOGICAL SURGERY MEDICINE
Najmunnisa, Nasreen PhD Research Assistant Professor PULMONARY MEDICINE MEDICINE
Naranjo, Arlene PhD Research Assistant Professor BIOSTATISTICS PHHP-COM INTEGRATED PROGRAMS
Nichols, Romaine C. MD Clinical Associate Professor RADIATION ONCOLOGY MEDICINE
Norkin, Maxim MD, PhD Clinical Assistant Professor HEMATOLOGY/ONCOLOGY MEDICINE
Okunieff, Paul MD Chair / Professor RADIATION ONCOLOGY MEDICINE
Ostrov, David A. PhD Associate Professor PATHOLOGY MEDICINE
Polfer, Nicolas C. PhD Associate Professor CHEMISTRY-GENERAL LIB ARTS / SCIENCES
Rahman, Maryam MD Assistant Professor NEUROLOGICAL SURGERY MEDICINE
Reisman, David MD, PhD Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
Reynolds, Brent PhD Associate Professor NEUROLOGICAL SURGERY MEDICINE
Rinaldi, Carlos PhD Associate Chair / Professor BIOMEDICAL ENGINEERING ENGINEERING
Sarkisian, Matthew R. PhD Assistant Professor NEUROSCIENCE-GENERAL MEDICINE
Sawyer, W. Gregory PhD Professor MECHANICAL / AEROSPACE ENG ENGINEERING
Sayour, Elias J. MD Assistant Professor NEUROLOGICAL SURGERY MEDICINE
Scarborough, Mark T. MD Chair & Professor ORTHOPAEDICS / REHAB MEDICINE
Schmittgen, Thomas PhD Professor PHARMACEUTICS PHARMACY
Scott, Edward W. PhD Program Director & Professor MOLECULAR GENTCS / MICROBIO MEDICINE
Sharma, Blanka PhD Assistant Professor BIOMEDICAL ENGINEERING ENGINEERING
Siemann, Dietmar W. PhD Associate Chair / Professor RADIATION ONCOLOGY MEDICINE
Slayton, William MD Chief & Associate Professor PEDS-HEMATOLOGY MEDICINE
Slopsema, Roelf MSc Clinical Associate Professor RADIATION ONCOLOGY MEDICINE
Spiguel, Lisa MD Clinical Assistant Professor GENERAL SURGERY – ADMIN MEDICINE
Staal, Stephen MD Program Director / Clinical Professor HEMATOLOGY/ONCOLOGY MEDICINE
Stechmiller, Bruce K. MD Clinical Associate Professor HEMATOLOGY/ONCOLOGY MEDICINE
Strekalova, Yulia A. MS, MBA Research Assistant Professor GRADUATE STUDIES / RESEARCH JOURNALISM & COMMUNICATIONS
Tan, Weihong PhD Distinguished Professor CHEMISTRY-GENERAL LIB ARTS / SCIENCES
Trame, Mirjam N. PharmD, PhD Assistant Professor PHARMACEUTICS PHARMACY
Tran, David D. MD, PhD Chief & Assistant Professor NEUROLOGICAL SURGERY MEDICINE
Vulpe, Christopher D. MD, PhD Professor PHY SCI VETERINARY MEDICINE
Wingard, John R. MD Deputy Director of Research / Program Director / Eminent Scholar HEMATOLOGY/ONCOLOGY MEDICINE
Wynn, Tung T. MD Program Director / Clinical Assistant Professor PEDS-HEMATOLOGY MEDICINE
Xing, Chengguo (Chris) PhD Professor MEDICINAL CHEMISTRY Pharmacy
Zajac-Kaye, Maria PhD Associate Professor ANATOMY-GENERAL MEDICINE