UF Health Cancer Center at the AACR Annual Meeting 2025

The American Association for Cancer Research (AACR) is the first and largest cancer research organization dedicated to accelerating the conquest of cancer. Through its programs and services, the AACR fosters research in cancer and related biomedical science, accelerates the dissemination of new research findings among scientists and others dedicated to the conquest of cancer, promotes science education and training, and advances the understanding of cancer etiology, prevention, diagnosis and treatment throughout the world.

The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research — from population science and prevention to cancer biology, translational and clinical studies to survivorship and advocacy — and highlights the work of the best minds in research and medicine from institutions all over the world.

The AACR Annual Meeting 2025 is April 25-30 in Chicago. Check out University of Florida presentations below. UF Health Cancer Center members appear in bold.


Major Symposiums

Session SY45 – Harnessing the Microbiota to Transform Cancer Immunotherapy
Bacterial-derived small molecules in the treatment of cancer
April 28 | 10:45-11:05 a.m.
Christian Jobin

Mini Symposiums

Session MS.IM01.02 – Checkpoints and Modulators of Tumor Microenvironment
6402 – Stress-induced HDAC8 reprogramming drives IL-11-mediated immune escape in melanoma
April 29 | 2:35-2:55 p.m.
Michael F. Emmons, Chao Zhang, Zhihua Chen, Richard L. Bennett, Olga Vera, Manali S. Phadke, Kanchan Gupta, Florian A. Karreth, Jonathan D. Licht, Keiran S. M. Smalley

Session MS.MCB06.01 – Epigenetic Regulation and Its Impact on Drug Response, Disease Pathogenesis, and Outcomes Across Pediatric and Adult Cancers
6409 – Epigenetic regulation of drug and disease related genes impact outcomes in pediatric AML
April 29 | 2:35-2:50 p.m.
Naifah Alshameri, Francisco Marchi, Xueyuan Cao, Stanley Pounds, Jatinder Lamba

6411 – The histone H3 E97K oncohistone creates a cellular histone H3 deficit and disrupts nucleosome stability
April 29 | 3:05-3:20 p.m.
Jixiu Shan, Richard L. Bennett, Pierre Priam, Kimberly N. E. Pereira, Shuxiang Li, James Rober, Maria Aristizabal, Anna R. Panchenko, Jonathan D. Licht

Advances in Prevention Research

Session APRV06 – Epstein-Barr Virus Associated Oncogenesis
The Oncovirus EBV rewires DNA repair via STAT3 exposing synthetic lethal vulnerabilities
April 28 | 1-1:20 p.m.
Sumita Bhaduri-McIntosh

Late-breaking poster session

LB082 / 18 – Disrupting lipid metabolism in GBM: A systems biology approach to targeting treatment-resistant persister cells and tumor associated myeloid cell-mediated support
April 27 | 2-5 p.m.
Avirup Chakraborty, Changlin Yang, Diana Feier, Aryeh Silver, Nyla T. Searl, Miruna Anica, Avinash Pittu, Illena West, Olusegun O. Sobanjo, Ethan D. Hodge, Mia K. Engelbart, Srabasti Sengupta, Nagheme Thomas, Christina Von Roemeling, Maryam Rahman, Matthew Sarkisian, Jianping Huang, Jeffrey Harrison, Duane A. Mitchell, Loic P. Deleyrolle

LB117 / 18 – AI for decoding spatial organization and molecular convergence in angiosarcoma
April 28 | 9 a.m.-12 p.m.
Donghee Lee, Rohith Sai Reddy Kondreddy, Hyunji JoJong Hyuk Kim

LB419 / 1 – HDAC8 over-expression promotes drug resistance and alters chromatin architecture in melanoma cells
April 30 | 9 a.m.-12 p.m.
Kanchan Gupta, Richard L. Bennett, Michael F. Emmons, Yufeng Xiao, Guangrong Zheng, Keiran S. M. Smalley, Jonathan D. Licht

LB460 / 18 – Aberrant CRTC-CREB activation is required for the development and maintenance of LKB1-inactivated lung cancer
April 30 | 9 a.m.-12 p.m.
Xin Zhou, Wei Ni, Mu Yu, Xzaviar K. Solone, Yuping Sun, Lizi Wu

April 27 | 2-5 p.m.

1086 / 26 – Introducing the Florida Cancer Research (FL CARES) Network and the Platform for Accelerating Collaborative Computational Cancer Research (PAC3R)
Michael Sinclair, Carlos Obregon, Caty Chung, Dusica Vidovic, Lukas Rupprecht, Jeronimo Pissinis, Marcin Pilarczyk, Franklin Sotolongo, Kathleen M. Jagodnik, Till Krenz, Erin Kobetz, Mondal M. Ananda, Ling Cen, Xuefeng Wang, Appu Rathinavelu, Stuart Chalk, Jiang Bian, Ji-Hyun LeeQianqian Song, Vasileios Stathias, Stephan C. Schürer

1055 / 9 – Inclusion of large genomics databases in disease modeling improves outcomes across ancestral populations
Leslie A. Smith, Franco Krepel, James A. Cahill, Ji-Hyun Lee, Kiley Graim

628 / 9 – Enhancing data integrity in contact registries: Methods for preventing fraudulent enrollment
IIeana Guzman, Nazleen Del Rio, Brooke Hensel, Eduardo Ibarra, Carolina Aristizabal, John Luque, Rosa Barahona, Diana Wilkie, Mariana C. Stern, Lourdes Baezconde-Garbanati, Sandra Suther, Fern Webb

804 / 23 – Gut microbiota, health-promoting lifestyle behaviors, and symptoms of pain and fatigue in hematopoietic cell transplantation survivors
Elham Samami, Angela Starkweather, Debra Lyon, Debra Kelly

545 / 7 – RFX5 knockdown restores sensitivity to cellular cyclophosphamide in triple-negative breast cancer cell lines
Elizabeth Katherine Molchan, Kathleen Streeks, Alyssa Ohaegbulam, Mohammed Gbadamosi

226 / 20 – Methylation specific silencing of miR-9 is associated with an epithelial-mesenchymal transition (EMT) phenotype in laryngeal squamous cell carcinoma
Christina Gobin, Matthew Chang, Marie Gauthier, Chayil C. Lattimore, Michael Kladde, Kristianna Fredenburg

274 / 18 – Resistance to VEGFR inhibitors converges from molecular diversity in angiosarcoma cells
Eslenur Nipa, Donghee Lee, Sun Hee Choi, Jong Hyuk Kim

45 / 24 – PDX technology transfer: NCI cancer center to HBCU
Teni O. Akin-Olugbemi (equal contribution), De’llaijah Lucas (equal contribution), Romell Stone, Esther Frimpong, Raviteja Bulusu, Hernan Flores-Rozas, Edward Agyare, Tanise Jackson, Renee Reams, Seth Ablordeppey, Brooke Hensel, Jose Trevino, Steven J. Hughes, Han Song, Christina Gobin, Bodour Salhia, Paul Okunieff, Kristianna Fredenburg, John M. Allen, Bereket Mochona, Diana J. Wilkie

626 / 7 – Black/African American participation in cancer clinical trials: Healthcare professional perspectives
Linda Kaljee, Sylvester Antwi, Doreen Dankerlui, Donna Harris, Barbara Israel, Denise White-Perkins, Valerie Ofori Aboah, Livingstone Aduse-Poku, Harriet Larrious-Lartey, Barbara Brush, Chris Coombe, La’Toshia Patman, Nayomi Cawthorne, Sophia Chue, Zachary Rowe, Cassandra Mills, Kurt Fernando, Gwendolyn Daniels, Eleanor Walker, Evelyn M. Jiagge

794 / 13 – Comprehensive outcomes for after cancer health (COACH): Interim analysis of physical function data for individuals with diverse tumor types following primary cancer therapy
Marilyn Hammer, Robin Lally, Barbara Halpenny, Hajime Uno, Ijeoma Eche-Ugwu, Whitney Posada, Inga Van Wieren, Alexi Wright, Ayodeji Adeniji, Sarah Alzahid, Lauren A. Anderson, Betty Arceneaux, Jerry Armah, Elizabeth Arthur, Kristen Fessele, Laura Flora, Alyssa Garcia, Anneliese Gonzalez, Michael Harrison, Brian Hulbert, Mariah Jackson, Kaukab Jafry, Rebecca Johnson-Beller, Abbey Kaler, Ginny Kirklin, Jessica Krok-Schoen, Hilda H. Lewis, Jennifer Loftis, Debra Lyon, Kathrin Milbury, Ariana Mohan, Jasmine Moore, Estee Murray-Ross, Darcy Ponce, Leorey Saligan, Elham Samami, Rachael Schmidt, Grace Smith, Angela Starkweather, Maria Chang Swartz, Martha Thompson, Gisele Tlusty, Meagan Whisenant, Gloria Yang, Kelly J. Brassil

April 28 | 9 a.m. to noon

1637 / 24 – GPX4-mediated Pathway Regulates Iron Efflux to Prevent Ferroptotic Cell Death and Promote Immunosuppressive Signals in Osteosarcoma Cells
Md Abdullah, Donghee Lee, Rong Li, Eslenur Nipa, Jong Hyuk Kim

1234 / 18 – Mechanical control of cancer-associated adipocyte plasticity orchestrates pancreatic cancer progression
Bo Han, Zhi Yang, Shuqing Zhao, Thomas Schmittgen, Jamel Ali, Jonathan Barajas, Carolyn Ruiz-Rivera, Ba Xuan Hoang

2193 / 17 – Patient-derived colorectal microtumors predict response to anti-PD1 therapy
Duy T. Nguyen, Matthew A. Schaller, Krista P. Terracina, Xia Xu, Diego I. Pedro, Alfonso Pepe, Juan M. Urueña, Zadia Dupee, Nickolas Diodati, Ryan Smolchek, Jack E. Famiglietti, Tran Yen Nhi Nguyen, Gerik Tushoski, Kuoyuan Cheng, Lan Chen, Doug Linn, Vania Vidimar, Aquila Fatima, Soon Woo Kwon, Dongyu Sun, Hongmin Chen, Haiyan Xu, Brian Long, Lily Y. Moy, Bonnie J. Howell, George H. Addona, W. Gregory Sawyer

1754 / 6 – Evaluating the synergism between circadian clock compounds with chemoradiation against GBM
Priscilla Chan, Yoshiko Nagai, Qiulian Wu, Jiarui Wang, Theodore Kamenecka, Laura A. Solt, Jamie Cope, Tsuyoshi Hirota, Jeremy N. Rich, Steve A. Kay

April 28 | 2-5 p.m.

CT063 / 8 – First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies (NCT04886622)
Daruka Mahadevan, Minal Barve, Devalingam Mahalingam, Jay Parekh, Michael Kurman, James Strauss, Larry Tremaine, Robert Hromas, Joshua Sills, John McCulloch, John Harkey, Stacy Suberg, Lisa Zimmerman, Guangrong Zheng, Daohong Zhou

3049 / 18 – Synergistic growth-inhibitory efficacy of LSD1 and BCL-XL inhibitors in JAK2+ AML/MPN cells
Mark A. Forsberg, Zhe Wang, Sovira Chaudhry, Anna Skwarska, Raajit Rampal, Alexandra Schurer, Kira Gritsman, Guangrong Zheng, Daohong Zhou, Marina Konopleva

2736 / 4 – Mutation of histone H2A at glutamate 121 is frequently observed in cancer patient samples and promotes cancer-associated cellular properties
Richard L. Bennett, Jixiu Shan, Anthony J. Lamberto, Rishika Cherukuru, Kimberly Espinoza Pereira, Pierre Priam, Jonathan D. Licht

3626 / 19 – Deoxycytidine kinase (dCK) gene expression patterns and racial disparities: Findings from the Multiethnic Cohort study
Saunjoo Yoon, Sherise Rogers, David Bogumil, Edward Agyare, Renee Reams, Mariana Stern, Seth Ablordeppey, Diana J. Wilke, Bo Han

3632 / 25 – Analysis of supportive care medication use in metastatic colorectal cancer across racial and ethnic groups using SEER-Medicare
Olga Trejos Kweyete, Yi Guo, Sherise Rogers, Lisa Scarton, David DeRemer, Diana Wilkie, John Allen

3633 / 26 – Exploring racial and ethnic disparities in supportive medication use for nonmetastatic colorectal cancer: a SEER-Medicare database analysis
Olga Trejos Kweyete, Yi Guo, Sherise Rogers, Lisa Scarton, David DeRemer, Diana Wilkie, John Allen

2623 / 26 – Targeted therapy with DFMO and immunotherapy equalizes survival in MYCN-amplified neuroblastoma: insights from genomic and network analyses
Anderson O. Cox, Abhinav Nagulapally, Deha Ay, Qianqian Song, Liang Liu, Hong-Gang Wang, Abigail Moore, Valerie I. Brown, Wei Zhang, Giselle L. Saulnier Sholler

2578 / 13 – GDF15 reprograms the microenvironment to drive the development of uveal melanoma liver metastases
Sathya Neelature Sriramareddy, Navya Siddarajappa, Thanh Nguyen, Jeffim Kunetsov, Stefan Kurtenbach, James Jarad Dollar, Jonathan D. Licht, Ann Y. Chen, William J. Harbour, Keiran S. M. Smalley

2743 / 11 – The H2B-E76K oncohistone alters chromatin accessibility, composition, and gene expression to induce EMT
Pierre Priam, Kimberly Espinoza Pereira, Jixiu Shan, Anthony Lamberto, Jay Sarthy, Wuyue Zhou, Ciaran Seath, Richard L. Bennett, Jonathan D. Licht

April 29 | 9 a.m. to noon

5042 / 13 – The Paipu pipeline for pan-mammalian cancer genomics
Bria S. Smith, Geesa V. Daluwatumulle, Leslie A. Smith, James A. Cahill, Kiley Graim

4468 / 10 – Modified 5-FU immunoliposome targeting EGFR-expressing pancreatic tumors: In vitro and in vivo evaluation
Esther Frimpong, Raviteja Bulusu, Joy Okoro, Xue Zhu, Renee Reams, Bo Han, Saunjoo Yoon, Edward Agyare

4475 / 17 – Evaluation of targeted immunoliposomes encapsulating 4-N-hydroxylgemcitabine in EGFR-positive pancreatic cancer
Joy Okoro, Raviteja Bulusu, Esther Frimpong, Saunjoo Yoon, Bo Han, Renee Reams, Xue Zhu, Edward Agyare

4477 / 19 – Biological evaluation of EGFR- conjugated liposomal drug delivery system for enhanced targeting of pancreatic cancer
Raviteja Bulusu, Joy Okoro, Esther Frimpong, Saunjoo Yoon, Bo Han, Renee Reams, Zhu Xue, Edward Agyare

4355 / 20 – Investigating the role of CXCR6 signaling in sorafenib resistance in HCC
Morgan Reeves, Satyamaheshwar Peddibhotla, Siobhan Malany

4358 / 23 – Single nucleotide polymorphisms located in PK/PD pathway genes of standard AML chemotherapy regimen predicts outcome in pediatric AML
Aneesha Nath, Richard Marrero, Xueyuan Cao, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba

4837 / 7 – NSD2 modulates immune surveillance in multiple myeloma
Amin Sobh, Daphne Dupere-Richer, Emilie Bonilla, Guya Avshara, Karthik Vasan, Monica Clerio, Richard Bennett, Navdeep S. Chandel, Jonathan D. Licht

4164 / 14 – Targeting glycogen metabolism as a potential therapy for Ewing sarcoma
Yueying Liu, Pankaj K. Singh, Lyndsay E. A. Young, Harrison A. Clarke, Tara R. Hawkinson, Meagan L. McCall, Elias Sayour, Craig W. Vander Kooi, Li Chen, Ramon C. Sun, Matthew S. Gentry

4974 / 21 – Leveraging partnerships through a Florida Innovation Grant: A collaborative approach by the Care2 Health Equity Center
Nazleen Del Rio, Brooke Hensel, Ileana Guzman, Sandra Suther, Fern J. Webb, Paul Okunieff, Diana Wilkie

4221 / 7 – Precision targeting of HDAC3 in ovarian cancer
Vijayalaxmi G. Gupta, Bisiayo Fashemi, Reni Akande, Preedia Babu, Yukihide Ota, Yufeng Xaio, Guangrong Zhang, Francisca Nathalia Vitorino, Benjamin Garcia, Mary Mullen, Dineo Khabele

4904 / 15 – Say it ain’t psoas: addressing edema in pancreatic cancer body composition analyses
Evan W. Davis, Margaret A. Park, Toni L. Basinski, J. Pablo Arnoletti, Francisca Beato, Mark Bloomston, Tiffany L. Carson, Tiago Biachi de Castria, Dung-Tsa Chen, Elena M. Cortizas, Sylvia L. Crowder, Maria Genilo-Delgado, Wade G. Douglas, Kevin L. Huguet, Kun Jiang, Pamela J. Hodul, Aleksandra Karolak, Dae Won Kim, John Koomen, Anjana A. Menon, Kenneth Meredith, Qianxing Mo, Shaffer R. Mok, Lina Moreno-Urazan, Sabeen Ahmed, Nathan Parker, Jose M. Pimiento, Ghulam Rasool, Lauren M. Sparks, Paul Stewart, Alexandra F. Tassielli, Jamie K. Teer, Dan Viet Tran, Jose G. Trevino, Vic Velanovich, Xuefeng Wang, Christopher J. Whelan, Sarah M. Judge, Andrew R. Judge, Jason B. Fleming, Daniel Jeong, Jennifer B. Permuth

3998 / 14 – Exploring fibroblast’s influence on chemoresistance in PDAC using patient-derived organoids
Jonathan Barajas, Carolyn Ruiz, Zhi Yang, Edward Agyare, Saun-Joo Yoon, Ba Xuan Hoang, Bo Han

3920 / 13 – The role of humanized monoclonal antibody ALT-100 in reducing cancer-induced bone pain: A murine animal model study
Nikhil C. Mathur, Ethan Villarroel, Isabella Villarroel, Erfan Bahramnedjad, Sally Dickinson, Joe G. N. Garcia, Tally Largent-Milnes, Todd W. Vanderah

4966 / 13 – Understanding social capital and health care treatment delays for cervical cancer survivors: a cross-sectional study using All of Us data.Samantha Garcia, Angel Arizpe, Albert J. Farias, Brittany N. Morey, Brenda Y. Hernandez, Lawrence A. Palinkas, Lourdes Baezconde-Garbanati, Jennifer Tsui

April 29 | 2-5 p.m.

6301 / 15 – ARLVPI: A novel machine-learning-informed platform for assessing somatic variant classification and pathogenicity
Arlen Larry Gyden, Nicole Ambroise, Tarsus Lam, Zehra Ordulu, Petr Starostik, Kimberly Newsom, Mohammed Gbadamosi

5841 / 17 – SARS-CoV-2 mRNA vaccines sensitize tumors to immune checkpoint blockade
Adam Grippin, Christiano Marconi, Sage Copling, Priti Gupta, Elliana Young, Padmanee Sharma, Don Gibbons, Hai Tran, Yon Son Betty Kim, Jianjun Zhang, Jennifer Wargo, John V. Heymach, Hector Mendez-Gomez, Wen Jiang, Elias Sayour, Steven H. Lin

CT228 / 20 – Talazoparib (Tala) in patients (pts) with solid tumors with ATM alterations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study
Elie G. Dib, Michael Rothe, Pam K. Mangat, Elizabeth Garrett-Mayer, Dustin Bivins, Mark Gitau, Apar K. Ganti, Arthur Winer, Vijay Suhag, Darryl Outlaw, Michael J. Hall, Olatunji B. Alese, Reza Nazemzadeh, Evan Pisick, Fengting Yan, Navid Hafez1, J. Calfa, Lex Leonhardt, David DeRemer, Abigail Gregory, Dominique C. Hinshaw, Gina N. Grantham, Susan Halabi, Richard L. Schilsky

5605 / 15 – Development of a novel protein phosphatase 2A (PP2A) activator, PPA27, as a potential therapeutic for melanoma
Hannah Johnson, Amandeep Singh, Asif Raza, Satya Narayan, Arun K. Sharma

5641 / 19 – Role of ceramide synthase 2 in drug-induced ER-stress, Ca2+ release and apoptosis in triple-negative breast cancer cells
Alatawi Hissah, Nair Haritha, Timothy Garrett, Christopher Vulpe, Arun Sharma, Satya Narayan

6342 / 23 – Ensuring diverse in vitro lung cancer models: development of alveolar epithelial cell lines from individuals of African ancestry
Bianca Dal Bó, Sofia A. Lugo, David M. Lee, Kweku Ofosu-Asante, Kyle R. Phillips, Benjamin J. Ryder, Yong Huang, Nazarius S. Lamango, Ite A. Offringa

6231 / 26 – Associations of serum concentrations of α- and γ-tocopherols with cancer mortality
Yoo-Min Koh, Jae Jeong Yang, Young-Rock Hong, Shama Karanth, Dejana Braithwaite, Hyung-Suk Yoon

6191 / 10 – Associations of alcohol consumption with expression of CD44, CD24, and ALDH1A1 stem cell markers in incident benign breast biopsy samples
Rulla M. Tamimi, Maisey Ratcliffe, Yu Jing J. Heng, Brian Sardella, Lusine Yaghjyan

6349 / 30 – Degradation of Aurora Kinase A, Alters Immune Checkpoint Expressions in Prostate Cancer
Sanjeev Shukla, Arjun Venkatesh, Jean-Pierre Kanumuambidi, Reynier D. Rodriguez Rosales, Mohammed Al-Toubat, Shelby Sparks, Adriana Yamaguchi, Steven Fletcher, K.C. Balaji

April 30 | 9 a.m. to noon

6899 / 15 – Investigating the impact of CXCR6 antagonism on Wnt/β-catenin signaling and sorafenib resistance development
Anastasia G. Chambers, Abhishek Shrestha, Morgan Reeves, Alivia Cullu, Lauren Donohue, Sergio Duarte, Satyamaheshwar Peddibholta, Siobhan Malany, Ali Zarrinpar

6790 / 2 – Exploring sensitivity and resistance to proteasome inhibitors in TP53 mutated non-small cell lung carcinoma
Victoria Neely, Kranthi Kumar Chougoni, Bin Hu, Jennifer E. Koblinski, Guangrong Zheng, Daohong Zhou, Swati Palit Deb, Sumitra Deb, Jorge J. Nieva, Senthil K. Radhakrishnan, Steven R. Grossman, Hisashi Harada

6827 / 12 – Developing lung adenocarcinoma cell lines to test new drugs and mitigate lung cancer health disparities
Kweku Ofosu-Asante, Sofia Lugo, Bianca Dal Bo, Matthew A. Gladstone, Chunli Yan, Daniel J. Mullen, Kyle R. Philips, Benjamin J. Ryder, Yong Huang, Ite A. Offringa, Nazarius S. Lamango

6662 / 17 – Deciphering molecular network complexity of oncogenic PIK3CA through proximity labeling
Rong Li, Donghee Lee, Md Abdullah, Eslenur Nipa, Jong Hyuk Kim

6723 / 17 – Targeting RAS in angiosarcoma
Donghee Lee, Eslenur Nipa, Erin B. Dickerson, Jong Hyuk Kim

7113 / 23 – Barriers to cancer diagnosis and treatment among women in low- and low-middle-income countries
Sylvester Antwi, Kwabena Agbedinu, Livingstone Aduse-Poku, Foster Amponsah, Harriet Larrious-Lartey, Samuel Mensah, Josephine Nsaful, Patrick Akakpo, Veneranda Nyarko, Michael Nortey, Alex Mremi, Theresia Mwakyembe, Valerie Ofori Aboah, Moses Dokurugu, Mohammed Sheriff, Nelson Affram, Evelyn M. Jiagge


CaRE2 at AACR 2025

AACR Nominating Committee
Mariana C. Stern, PhD, 2025-2027

Session Chair, April 25 | 1-4 p.m.

Session PDS01 – Grant Writing Workshop: Tips for Success from Experienced Scientists. Mariana C. Stern

Session Chair, April 26 | 8 a.m.

Session ED41 – Social Determinants of Health and Cancer Outcomes: From the Sidewalk to the Bench and Back Again. Chanita Hughes Halbert

Session Chair, April 27 | 7 a.m. – 8:30 a.m.

Session CDF01 – Lifelong Career Development: Strategies for Success . Mariana C. Stern

Mini-symposium

April 27 | 4:50-5:00 p.m.

The Bench with Bedside InitiativeTM: an unconventional collaborative approach between scientists and research participants. Audrey Saghian, Alex J. Kalfa, Robel Dagnew, Navid Golshan, Raed Jaffal, Dayanara Ruiz, Mary K. Falcone, Caryn Lerman, Bodour Salhia

April 28 | 2-5 p.m.

3632 / 25 – Analysis of supportive care medication use in metastatic colorectal cancer across racial and ethnic groups using SEER-Medicare. Olga Trejos Kweyete, Yi Guo, Sherise Rogers, Lisa Scarton, David Deremer, Diana Wilkie, John Allen

3633 / 26 – Exploring racial and ethnic disparities in supportive medication use for nonmetastatic colorectal cancer: a SEER-Medicare database analysis. Olga Trejos Kweyete, Yi Guo, Sherise Rogers, Lisa Scarton, David Deremer, Diana Wilkie, John Allen

April 29 | 2:35-2:50 p.m.

6409 – Epigenetic regulation of drug and disease related genes impact outcomes in pediatric AML. Naifah Alshameri, Francisco Marchi, Xueyuan Cao, Stanley Pounds, Jatinder Lamba

Poster sessions

April 27 | 2-5 p.m.

45 / 24 – PDX Technology Transfer: NCI Cancer Center to HBCU. A-O, Oluwateniola (equal contribution), Lucus, D.(equal contribution), Stone, R.,  Frimpong, E., Bulusu, R., Okoro, J., Flores-Rozas, H., Agyare, E., Jackson, T., Reams, R., Ablordeppey, S., Hensel, B., Trevino, J., Hughes, S. J., Han, S., Gobin, C., Salhia, B., Okunieff, P., Fredenburg, K.,  Allen, J., Machona, B., & Wilkie, D. J.

628 / 9 – Enhancing data integrity in contact registries: Methods for preventing fraudulent enrollment. IIeana Guzman, Brooke Hensel, Eduardo Ibarra, Carolina Aristizabal, John Luque, Rosa Barahona, Diana Wilkie, Mariana C. Stern, Lourdes Baezconde-Garbanati, Sandra Suther, Fern Webb

631 / 12 – Building Bridges Between Communities and Cancer Researchers through the CaRE2 Health Equity Center Community Scientist Research Advocacy Program. Aristizabal, Carolina; Ibarra, Eduardo; Hensel, Brooke; Del Rio, Nazleen; Guzman, Ileana; Barahona, Rosa; Rodriguez, Janet; Webb, Fern J.; Suther, Sandra; Luque, John; Stern, Mariana C.; Baezconde-Garbanati, Lourdes

987 / 21 – Enhancing oncology navigation services: a mixed methods approach to developing an EHR power form to improve metrics and reporting. Kelsie Campbell, Joi Torrence-Hill, Karey A. Whitten, Melissa Abbud, Jynette Querubin, Charis Stewart, Mariana Dobre, Trista A. Beard, Fatimata Sanogo, Chanita Hughes Halbert

April 28 | 9 a.m. to noon

2269 / 10 – Factors associated with declining to participate in cancer genetic and genomic studies among Hispanic/Latine patients with colorectal cancer: findings from a Cancer MoonshotSM project. Diego I. Alvarez-Lopez, Joel Sanchez Mendez, Jessica Sanchez, Fibi Berhane, Carmen Chavez, Lucia Enriquez, Vernon Shane Pankratz, Andrew L. Sussman, Ursa Brown-Glaberman, Stephanie Solomon Cargill, Heinz-Josef Lenz, John D. Carpten, Shiraz I. Mishra, Mariana C. Stern

1234 / 18 – Mechanical control of cancer-associated adipocyte plasticity orchestrates pancreatic cancer progression. Bo Han, Zhi Yang, Shuqing Zhao, Thomas Schmittgen, Jamel Ali, Jonathan Barajas, Carolyn Ruiz-Rivera, Ba Xuan Hoang

April 28 | 2-5 p.m.

3626 / 19 – Deoxycytidine Kinase (dCK) gene expression patterns and racial disparities: Findings from the Multiethnic Cohort Study. Yoon, S. L., Rogers, S., Bogumil, D., Agyare, E., Reams, R., Stern, M., Ablordeppey, S., Wilkie, D. J., & Han, B

Panelist, April 29 | 10:15 a.m.

Session SY49 – Minorities in Cancer Research Scientific Symposium: Using Self-identified Race/Ethnic Categories in Cancer Disparities Research in the Era of Precision Medicine. Chanita Hughes Halbert, PhD

April 29 | 9 a.m. to noon

4468 / 10 – Modified 5-FU immunoliposome targeting EGFR-expressing pancreatic tumors: In vitro and in vivo evaluation. Esther Frimpong, Raviteja Bulusu, Joy Okoro, Xue Zhu, Renee Reams, Bo Han, Saunjoo Yoon, Edward Agyare

4026 / 16 – The Bench with Bedside InitiativeTM: an unconventional collaborative approach between scientists and research participants. Audrey Saghian, Alex J. Kalfa, Robel Dagnew, Navid Golshan, Raed Jaffal, Dayanara Ruiz, Mary K. Falcone, Caryn Lerman, Bodour Salhia

3998 / 14 – Exploring Fibroblast’s Influence on Chemoresistance in PDAC using Patient-Derived Organoids. Jonathan Barajas, Carolyn Ruiz, Zhi Yang, Edward Agyare, Saun-Joo Yoon, Ba Xuan Hoang, Bo Han

4475 / 17 – Evaluation of Targeted Immunoliposome encapsulating 4-N-hydroxylGemcitabine in EGFR-positive Pancreatic Cancer. Joy Okoro, Raviteja Bulusu, Esther Frimpong, Saunjoo Yoon, Bo Han, Renee Reams, Xue Zhu, Edward Agyare

4974/ 21 – Leveraging partnerships through a Florida Innovation Grant: A collaborative approach by the CaRE2 Health Equity Center. Del Rio, Nazleen; Hensel, Brooke; Guzman, Ileana; Suther, Sandra; Webb, Fern J; Okunieff, Paul; Wilkie, Diana

4358 / 23 – Single nucleotide polymorphisms located in PK/PD pathway genes of standard AML chemotherapy regimen predicts outcome in pediatric AML. Aneesha Nath, Richard Marrero, Xueyan Cao, Jeffrey Rubnitz, Stanely Pounds and Jatinder K Lamba

4027 / 17 – Self-Confidence as a Driver of Community Impact: Outcomes of the Community Genetic Navigation Engagement Specialist (CoGENES) Train-the-Trainer Program. Bianca Rosales, Janet Rodriguez, Joel Sanchez Mendez, Yaneth L. Rodriguez, Charité Ricker, Rosa Barahona, Heinz Joseph-Lenz, John Carpten, Mariana C. Stern and Lourdes Baezconde-Garbanati

4477 / 19 – Biological evaluation of EGFR- conjugated liposomal drug delivery system for enhanced targeting of pancreatic cancer. Raviteja Bulusu, Joy Okoro, Esther Frimpong, Saunjoo Yoon, Bo Han, Renee Reams, Xue Zhu, Edward Agyare

Late-breaking poster session | 9 a.m. – 12 p.m.

LB271 / 20 – Faith in Cancer Equity: A community-centered approach to eliminating enrollment barriers to early phase trials in Black communities in Los Angeles County. Essence Wynter, Anthony El-Khoueiry, Chanita Hughes-Halbert, Lourdes Baezconde-Garbanati

April 29 | 2-5 p.m.

6185 / 4 – Integrating internships into the CaRE2 Health Equity Center: A pathway for developing future health equity leaders. Del Rio, Naleen, Hensel, Brooke, Guzman, Ileana, Ibarra, Educaro, Aristizabal, Carolina, Barahona, Rosa, Stern, Mariana, Luque, John, Baezconde-Garbanati, Lourdes, Suther, Sanra, Webb, Fern J

6206 / 1 – The role of lifestyle factors in the disparities of colorectal cancer incidence: Findings from the Multiethnic Cohort Study. Joel Sanchez Mendez, Jonanne Talebloo, Adelynn Paik, Sihao Han, Iona Cheng, Anna H. Wu, Ugonna Ihenacho, Lynne R. Wilkens, Loïc Le Marchand, David V. Conti, Christopher A. Haiman, Brian Z. Huang, Mariana C. Stern

5165 / 13 – Development of a syngeneic mouse model to study small cell lung cancer (SCLC). Aarushi Garg, Diego A. Velarde, Mario A. Pulido, Daniel J. Mullen, Chunli Yan, Matthew A. Gladstone, Ite A. Offringa

6342 / 23 – Ensuring diverse in vitro lung cancer models: development of alveolar epithelial cell lines from individuals of African ancestry. Bianca Dal Bó, Sofia A. Lugo, David M. Lee, Kweku Ofosu-Asante, Kyle R. Phillips, Benjamin J. Ryder, Yong Huang, Nazarius S. Lamango, Ite A. Offringa

April 30 | 9 a.m. – 12 p.m.

6827 / 12 – Developing lung adenocarcinoma cell lines to test new drugs and mitigate lung cancer health disparities. Kweku Ofosu-Asante, Sofia Lugo, Bianca Dal Bo, Matthew A. Gladstone, Chunli Yan, Daniel J. Mullen, Kyle R. Philips, Benjamin J. Ryder, Yong Huang, Ite A. Offringa, Nazarius S. Lamango

7243 / 19 – Mapping the isoaspartylation site(s) in the N-terminal region of ELAVL4 by using deletion constructs and testing against SCLC patient sera. Kweku Ofosu-Asante, Sofia Lugo, Bianca Dal Bo, Matthew A. Gladstone, Chunli Yan, Daniel J. Mullen, Kyle R. Philips, Benjamin J. Ryder, Yong Huang, Ite A. Offringa, Nazarius S. Lamango

7246 / 22 – A natural antibody response associated with improved survival of SCLC patients can be actively induced in a SCLC mouse model and leads to significantly improved survival. Diego Alejandro Velarde, Joseph Valdes, Chunli Yan, Sarah Elmalh, Hannah Lee, Daniel J. Mullen, Angie Moreno, Matthew A. Gladstone, Nicky Nie, Ming Li, Martin Kast, Ite A. Offringa

7100 / 10 – The relationship between social deprivation and immune suppression in Hispanic/Latina patients with breast cancer. Elexa P. Rallos, Sabrina Carrel, Michelle Li, Batul Al-Zubeidy, Edgar Gonzalez, Aaron G. Baugh, Matthew Jacobo, Cheol Park, Robert Hsu, Dominic Zavala, Steven Do, Michael F. Press, Ming Li, Anastasia Martynova, Priya Jayachandran, Daphne Stewart, Chanita Hughes-Halbert, Mariana C. Stern, Evanthia T. Roussos Torres

6821 / 6 – The Anticancer Effects of Polyisoprenylated Phosphonyl Ester Inhibitors (PPEIs) of PMPMEase in Pancreatic Cancer Cells. Jahnissi Odoom, Amarender Burra, Kweku Ofosu-Asante, Joshua Ablordeppey, Nazarius Lamango

Travel Awards

AACR Scholar In Training Award. Esther Frimpong

AACR Scholar In Training Award. Dayanara Ruiz

AACR Women in Cancer Research Award. Joy Okoro

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