The UF Health Cancer Institute will be well-represented at the American Society of Hematology (ASH) 67th Annual Meeting and Exposition in Orlando, Florida, from Dec. 6-9.
The ASH Annual Meeting is the world’s premier global hematology event, drawing more than 30,000 attendees. This was a record-breaking year with more than 8,200 accepted abstracts. View the full conference program.
The UF Health Cancer Institute is involved in 60 abstracts representing the full spectrum of hematology research, from leading-edge cellular therapies, to novel diagnostic methods incorporating AI, to health communications research.
UF Health Cancer Institute members appear below in bold. Other UF researchers and trainees are in italics.
Scientific Program
Mechanisms that Direct and Derail Lineage-Specific Transcription Factor Complexes
Chair: Olga Guryanova, M.D., Ph.D.
Monday, Dec. 8 | 2:45-4 p.m.
Oral Abstract Sessions
Acute Myeloid Leukemias – Biomarkers and Molecular Markers in Diagnosis and Prognosis – Decoding the Immunopathobiology of Acute Myeloid Leukemia
Moderator: Jatinder Lamba, Ph.D.
Monday, Dec. 8 | 10:30 a.m. – 12 p.m.
Oral Abstracts
Category: 300s – Hemostasis, Thrombosis and Vascular Wall Biology
End-of-study results from the ICON3 pines trial, a phase 3, randomized trial of eltrombopag vs. standard first-line treatment for newly diagnosed immune thrombocytopenia in children
Kristin Shimano, Amanda Grimes, Melissa Rose, Shipra Kaicker, Sanjay Shah, Michael Briones, Elizabeth Gunn, Taizo Nakano, Jeffrey Lebensburger, Michele Lambert, Stephanie Fritch Lilla, Rohith Jesudas, Cathy Lee-Miller, Alexis Thompson, Rukhmi Bhat, Stacey Rifkin-Zenenberg, Suvankar Majumdar, Manpreet Kochhar, Shelley Crary, Kerry Hege, Jennifer Rothman, James Ford, Joshua Bies, Tung Wynn, Loan Hsieh, Maritza Ruiz, Bogdan Dinu, Julia Wong, Pei-Chi Kao, Staci Arnold, Carolyn Bennett, Jenny Despotovic, Robert Klaassen, Ellis Neufeld, Cindy Neunert, Wendy London, Rachael Grace
Monday, Dec. 8 | 11:45 a.m. – 12 p.m.
Category: 500s – Hematopoiesis
Endothelial cell-derived thrombospondin-1 negatively affects hematopoietic function during aging
Arianna Smith, Cody Carter, Pradeep Ramalingam, Jason Butler
Sunday, Dec. 7 | 10-10:15 a.m.
Category: 600s – Hematologic Malignancy
Functional genomics studies identify determinants of response vs. resistance to pharmacological inhibitors of KRAS in multiple myeloma
Torsten Steinbrunn, Arnold Bolomsky, Ryosuke Shirasaki, Omar Al-Odat, Olga Dashevsky, Huihui Tang, Shizuka Yamano, Oliver Bohorquez, Brian Glassner, Eleni Anastasakou, Vikas Gupta, Jonathan Licht, Benjamin Barwick, Lawrence Boise, Ricardo De Matos Simoes, James Christensen, Ryan Young, Constantine Mitsiades
Saturday, Dec. 6 | 4:30-4:45 p.m.
Outcomes in children and adolescents with down syndrome and B-lymphoblastic leukemia: A report from Children’s Oncology Group study AALL1731
Amanda Li, John Kairalla, Cindy Wang, Meenakshi Devidas, Olga Militano, Johann Hitzler, Anne Angiolillo, Michael Burke, Wanda Salzer, Stephen Hunger, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Sumit Gupta, Rachel Rau, Karen Rabin
Sunday, Dec. 7 | 12-12:15 p.m.
NSD2 expression remodels DNA methylation, creating a targetable epigenetic dependency in t(4;14) multiple myeloma
Anna Baj, Jonathan Patton, Robert Chavez, Shannon Matulis, Doris Powell, Mala Shanmugam, Arun Wiita, Constantine Mitsiades, Jonathan Keats, Jonathan Licht, Sagar Lonial, Lawrence Boise, Benjamin Barwick
Sunday, Dec. 7 | 12:15-12:30 p.m.
Negative regulators of survival and proliferation (NRSPs) identified by CRISPR activation studies in multiple myeloma (MM) vs. other neoplasias: Therapeutic implications
Olga Dashevsky, Ricardo De Matos Simoes, Huihui Tang, Torsten Steinbrunn, Shizuka Yamano, Eleni Anastasakou, Benjamin Barwick, Sara Gandolfi, Ryosuke Shirasaki, Vikas Gupta, Michal Sheffer, Jonathan Licht, Lawrence Boise, Matthew Oser, Constantine Mitsiades
Sunday, Dec. 7 | 5:15-5:30 p.m.
Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children’s Oncology Group studies AALL0932 and AALL1131
Ruth Wang’ondu, Anne Angiolillo, Meenakshi Devidas, Karen Rabin, Michael Borowitz, Brent Wood, Andrew Carroll, Nyla Heerema, Emily Hibbitts, Reuven Schore, William Carroll, Michael Burke, Wanda Salzer, Lia Gore, Naomi Winick, David Teachey, Elizabeth Raetz, Mignon Loh, Stephen Hunger, John Kairalla
Monday, Dec. 8 | 10:30-10:45 a.m.
Blinatumomab mitigates the impact of traditional adverse prognosticators among children with standard risk b-acute lymphoblastic leukemia: Updated results of the Children’s oncology group (COG) Trial AALL1731
Sumit Gupta, Rachel Rau, John Kairalla, Karen Rabin, Cindy Wang, Anne Angiolillo, Sarah Alexander, Andrew Carroll, Susan Conway, Lia Gore, Ilan Kirsch, Holly Kubaney, Amanda Li, Jennifer McNeer, Olga Militano, Tamara Miller, Yvonne Moyer, Maureen O’Brien, Maki Okada, Shalini Reshmi, Mary Shago, Elizabeth Wagner, Naomi Winick, Brent Wood, Tara HaworthWright, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Meenakshi Devidas, Stephen Hunger, David Teachey, Mignon Loh, Elizabeth Raetz
Monday, Dec. 8 | 10:45-11 a.m.
Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium
Thai Hoa Tran, Meenakshi Devidas, Leyna Xoi, Andishe Attarbaschi, Judith Boer, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Yoshihiro Gocho, Mats Heyman, Stephen Hunger, Hiroto Inaba, Gabor Kovacs, Anthony Moorman, Charles Mullighan, Kjeld Schmiegelow, Jan Stary, Tomasz Szczepanski, David Teachey, Andrea Biondi, Mignon Loh, Rob Pieters, Sarah Elitzur
Monday, Dec. 8 | 11:30-11:45 a.m.
Factors associated with central nervous system relapse after b-acute lymphoblastic leukemia: A Children’s Oncology Group report
Aman Wadhwa, Lingyun Ji, Alice Dang, Xinxin Xu, Meenakshi Devidas, John Kairalla, Mary Shago, Nyla Heerema, Andrew Carroll, Michael Borowitz, Brent Wood, Eric Larsen, Kelly Maloney, Reuven Schore, Wanda Salzer, Michael Burke, Stephen Hunger, David Teachey, Naomi Winick, Elizabeth Raetz, Mignon Loh, Deepa Bhojwani, Sumit Gupta
Monday, Dec. 8 | 11:45 am.-12 p.m.
Initial results from a phase 2 study of cladribine, cytarabine, and granulocyte-colony stimulating factor with gemtuzumab ozogamicin (CLAG-GO) for the treatment of patients with relapsed/refractory acute myeloid leukemia
David Chen, Maria Baer, Sandrine Niyongere, Ashkan Emadi, Vivek Shastri, Jatinder Lamba, Michael Loken, Larissa Sanglard, Rena Lapidus, Soren Bentzen, Vu Duong
Monday, Dec. 8 | 5-5:15 p.m.
Category: 700s – Transplantation and Adoptive Cell Therapies
High event-free (EFS) and overall survival (OS) after non-total body irradiation (TBI) conditioning and allogeneic hematopoietic cell transplantation (HCT) in next-generation-sequencing minimal residual disease (NGS-MRD) negative B-acute lymphoblastic leukemia (B-ALL): Results from the EndRAD trial (PTCTC ONC1701)
Hisham Abdel-Azim, Troy Quigg, Neena Kapoor, Yueh-Yun Chi, Christine Higham, Amy Keating, Vanessa Fabrizio, Jodi Skiles, Shalini Shenoy, Sajad Khazal, Aliza Gardenswartz, Lisa Madden, Jordan Milner, Rachel Phelan, Emi Caywood, Ulrich Duffner, Jonathan Fish, Jorge Galvez Silva, Alfred Gillio, Rabi Hanna, Jeffrey Huo, Nahal Lalefar, Kris Mahadeo, Kevin McNerney, J. Gregory Dolan, Dana Salzberg, Heather Stefanski, Michael Pulsipher
Sunday, Dec. 6 | 12-12:15 p.m.
Reduced intensity haploidentical bone marrow transplantation in children with severe sickle cell disease (SCD): BMT CTN 1507
Mark Walters, Adetola Kassim, Mary Eapen, Jordan Milner, Robert Nickel, Alfred Gillio, Khaled Yassine, Jodi Skiles, Christopher McKinney, Hemalatha Rangarajan, Ghada Abusin, Jorge Galvez Silva, Michael Kent, Nicole Ritzau, Adam Mendizabal, Kris Mahadeo, Lakshmanan Krishnamurti, Kenneth Cooke, Eric Leifer, Rick Jones, Robert Brodsky, Michael DeBaun
Saturday, Dec. 6 | 12:15-12:30 p.m.
Mismatching of unrelated donors beyond a single HLA-locus does not adversely impact outcomes at one year following transplantation: Results from the NMDP sponsored ACCESS study
Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Sarah Smith, Erin Leckrone, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Brian Shaffer, Dipenkumar Modi, Farhad Khimani, Mahasweta Gooptu, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez
Monday, Dec. 8 | 4-4:15 p.m.
Time from AML diagnosis to HCT and pre-HCT FLT3 inhibition impact pre-transplant MRD and benefit from post-HCT gilteritinib
Mark Levis, Mehdi Hamadani, Brent Logan, Richard Jones, Anurag Singh, Mark Litzow, John Wingard, Esperanza Papadopoulos, Alexander Perl, Robert Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey Uy, Edmund Waller, Sumithira Vasu, Melhem Solh, Asmita Mishra, Lori Muffly, Heeje Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Caroline Chen, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley Gill, Rishita Nuthethi, Denise King, Adam Mendizabal, Steven Devine, Mary Horowitz, Yi-Bin Chen
Monday, Dec. 8 | 4:45-5 p.m.
Category: 800s – Gene Therapies, Chemical Biology, and Emerging Diagnostics
Transformer neural network using DNA methylation for sensitive and specific diagnosis of acute leukemia
Pedro V.B. Orsini, Francisco Marchi, Anna Lux, Laura F. Crosara, Jeffrey Rubnitz, Jeffery Klco, Jatinder Lamba
Saturday, Dec. 6 | 10:15-10:30 a.m.
Category: 900s – Health Services, Quality Improvement, and Outcomes Research
Inadequate social support and household material hardship among children with pediatric acute lymphoblastic leukemia: A report from the Children’s oncology group Trial AALL1731
Selena Murcia Mendez, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Rahela Aziz-Bose, Colleen Kelly, Haley Newman, Daniel Zheng, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona, Puja Umaretiya
Saturday, Dec. 6 | 10:45-11 a.m.
Strengthening the referral pathway: Community oncology clinician perspectives on referring to academic cancer centers
Jonathan Thomas, Naomi Parker, Margo Michaels, Stephanie Staras, Tithi Amin, Carma Bylund
Monday, Dec. 8 | 11:30-11:45 a.m.
The impact of a clinical trial communication training workshop on hematology-oncology Fellows’ knowledge, attitudes and behaviors: A mixed-methods evaluation
Carma Bylund, Susan Eggly, Daphne Friedman, Leah Szumita, Naomi Parker, Tithi Amin, Marie Michele Sainvil, Andrea Sitlinger, Stephanie Staras, Tuo Lin, Tara Hashemian, Elisa Weiss
Monday, Dec. 8 | 11:45 a.m.-12 p.m.
Exploring the relationship between health-related stigma and perceived discrimination among adults with sickle cell disease
Kholod Alhassan, Diana Wilkie, Miriam Ezenwa, Yingwei Yao, Charles Ellis, Coretta Jenerette, Laurie Duckworth
Monday, Dec. 8 | 5:15-5:30 p.m.
Poster Presentations
Category: 100s – Red Cell Physiology and Disorders
Pharmacogenetic variants in UGT1A1/UGT1A3 and ABCC2 associate with deferasirox efficacy in transfusion-dependent thalassemia
Chandni Patel, Vivek Shastri, Janel Long-Boyle, Johnny Li, Felicity Rose, Beth Apsel Winger, Jatinder Lamba
Saturday, Dec. 6 | 5:30-7:30 p.m.
Platelet proteomic signatures reveal neurodegenerative and mitochondrial pathways associated with pain phenotypes in sickle cell disease
Yenisel Cruz-Almeida, Margaret (Peggy) Wallace, Diana Wilkie
Sunday, Dec. 7 | 6-8 p.m.
Predictive value of lung function results for sleep-disordered breathing in children with sickle cell disease: A multicenter cross-sectional study
Ammar Alishlash, Anis Nourani, A K M Fazlur Rahman, Tarig Ali Dinar, Dima Ezmigna
Sunday, Dec. 7 | 6-8 p.m.
Impact of pain sensitization phenotypes on quality of life among adults with sickle cell disease
Rachael Ajiboye, Yingwei Yao, Yenisel Cruz-Almeida, Miriam Ezenwa, Zaijie Wang, Robert Molokie, Diana Wilkie
Monday, Dec. 8 | 6-8 p.m.
Category: 300s – Hemostasis, Thrombosis and Vascular Wall Biology
Real world outcomes in patients with acquired thrombotic thrombocytopenic purpura (TTP) treated with caplacizumab
Jawria Tufail, Zubair Hassan Bodla, Muhammad Junaid Tariq
Sunday, Dec. 7 | 6-8 p.m.
Category: 500s – Hematopoiesis
DNMT3A-driven clonal hematopoiesis permits colitis-associated tumorigenesis by promoting innate immune tolerance
Qingchen Yuan, Yang Feng, Christopher Thai, Andrey Smirnov, Eric Helm, Bowen Yan, Prabhjot Kaur, Annalisse McKee, Cassandra Berntsen, Daniil Shabashvili, Jixiu Shan, Jason Brant, Dorina Avram, Hossein Khiabanian, Jonathan Licht, Olga A Guryanova
Sunday, Dec. 7 | 6-8 p.m.
Netrin-1 regulates hematopoietic stem cell function via UNC5A
Bianca Bean, Pradeep Ramalingam, Jason Butler
Sunday, Dec. 7 | 6-8 p.m.
Endothelial SRSF1 regulates hematopoietic stem cell function in the bone marrow microenvironment
Kruti Bosmia, Agatha Winiarski, Cody Carter, Michael Poulos
Monday, Dec. 8 | 6-8 p.m.
Category: 600s – Hematologic Malignancy
Prognostic relevance of epigenetic regulation of drug pharmacology and myeloid genes in pediatric AML
Naifah Alshameri, Francisco Marchi, Soheil Meshinchi, Xueyuan Cao, Jeffrey Rubnitz, Raul Ribeiro, Stanley Pounds, Jatinder Lamba
Saturday, Dec. 6 | 5:30-7:30 p.m.
Age-related differences in presentation among pediatric, adolescent, and young adults with mixed cellularity vs. nodular sclerosis histology Hodgkin lymphoma on Children’s oncology group treatment and registry trials
Mallorie Heneghan, Lindsay Renfro, Yue Wu, Angela Feraco, Jamie Flerlage, Boyu Hu, Erin Marcotte, Cindy Schwartz, Kara Kelly, Sharon Castellino, Justine Kahn
Saturday, Dec. 6 | 5:30-7:30 p.m.
Interferon alfa treatment of early primary myelofibrosis is associated with improved overall survival
Katie Erdos, Mlaak Rob, Majed Al-Nazer, Neville Lee, Joseph Scandura, Richard Silver, Ghaith AbuZeinah
Saturday, Dec. 6 | 5:30-7:30 p.m.
The c-terminal to lish (CTLH) E3 ligase complex modulates myeloma glucocorticoid sensitivity by regulating nfkb signaling
Amin Sobh, Emilie Bonilla, Alberto Riva, Kalyanee Shirlekar, Alisha Patel, Jianping Li, Eric Murphy, Claudia McCown, Timothy Spicer, Kendall Nettles, Jonathan Licht
Saturday, Dec. 6 | 5:30-7:30 p.m.
Identification of novel “driver” genes of multiple myeloma through genome-scale CRISPR activation studies
Huihui Tang, Ricardo De Matos Simoes, Torsten Steinbrunn, Ryosuke Shirasaki, Olga Dashevsky, Eleni Anastasakou, Oliver Bohorquez, Shizuka Yamano, Evangelos Papadopoulos, Lisa Leypoldt, Arun Wiita, Olwyn Mahon, Vikas Gupta, Jonathan Licht, Benjamin Barwick, Lawrence Boise, Constantine Mitsiades
Saturday, Dec. 6 | 5:30-7:30 p.m.
Inhibition of NSD2 in t(4;14) myeloma induces changes in mitochondrial priming
Shannon Matulis, Jonathan Patton, Rebecca Owens, Robert Chavez, Arun Wiita, Mala Shanmugam, Constantine Mitsiades, Vikas Gupta, Jonathan Licht, Benjamin Barwick, Lawrence Boise
Saturday, Dec. 6 | 5:30-7:30 p.m.
Epigenetic basis of MDS/MPN overlap syndrome with compound loss of Kmt2c and Dnmt3a
Prabhjot Kaur, Jixiu Shan, Kalyanee Shirlekar, Erin C Hayslip, Qingchen Yuan, Bowen Yan, Annalisse R McKee, James M Leonard, Cassandra Berntsen, Daniil Shabashvili, Jason Brant, Richard L Bennett, Jonathan Licht, Olga A Guryanova
Sunday, Dec. 7 | 6-8 p.m.
Identification of therapeutic vulnerabilities in FLT3-mutated AML through customized CRISPR screens
Phani Krishna Parcha, Nam Nguyen, Abderrahmane Tagmount, Christopher Vulpe, Stanley Pounds, Jatinder Lamba
Sunday, Dec. 7 | 6-8 p.m.
Optimal therapy for pediatric B-ALL in first relapse: Comparative effectiveness of blinatumomab to hematopoietic cell transplantation versus CD19 CAR T cell therapy
Regina Myers, Yimei Li, Hongyan Liu, Alex Hoover, Laura Shinehouse, Ashley Hinson, Mira Kohorst, Anna Elias, Ella Keenan, Hannah Acres, Ibrahim Ahmed, Abdulla Al-Mulla, Laura Arthur, Jill Beck, Abigale Berry, Deepika Bhatla, Eliza Briscoe, Grace Chang, Roland Chu, Laurie Davis, J. Gregory Dolan, Lyannette Elo, Elizabeth Eom, Alejandra Escobar Vasco, Vanessa Fabrizio, Kelly Faulk, Victor Galan-Gomez, Erin Goode, Stephan Grupp, Anurekha Hall, Darcy Hamill, Smitha Vasanna, Hannah Kinoshita, Elizabeth Krieger, Cathy Lee-Miller, Katherine Lind, Jordan Milner, Giselle Moore-Higgs, Amy Moskop, Lindsey Murphy, Megan Murphy, Gabriella Nguyen, Maria Ortega, Hiren Patel, Antonio Perez, Thomas Pfeiffer, Alexandra Prosser-Dombrowski, Mahvish Rahim, April Rahrig, Shanti Ramachandran, Miza Salim Hammoud, Amanda Saraf, Jamie Shoag, Heather Symons, Nicholas Tastet, Stephanie Thomas, Molly Thornock, Keri Toner, Allison Weisnicht, Sara Zarnegar-Lumley, Nirali Shah, Shannon Maude, Jeremy Rubinstein, Troy Quigg, Deepa Bhojwani, Caitlin Elgarten
Sunday, Dec. 7 | 6-8 p.m.
Epigenetic priming improves survival for pediatric Acute Myeloid Leukemia: Results from the multicenter randomized AML16 trial
Tanja Gruber, Stanley Pounds, Norman Lacayo, Kenneth Heym, Meret Henry, Barbara Degar, Deborah Schiff, Faisal Razzaqi, Jamie Frediani, Samuel Milanovich, Jennifer McNeer, Huiyun Wu, Lakshmi Patibandla, Emily Xiong, Tamara Westover, Ryan Hiltenbrand, Lu Wang, Priya Kumar, Gabrielle Lapping-Carr, Kayelyn Wagner, Dennis Kuo, Jessica Pollard, Nickhill Bhakta, Seth Karol, Brandon Triplett, Jatinder Lamba, Hiroto Inaba, Ching-Hon Pui, Raul Ribeiro, Jeffrey Rubnitz, Jeffery Klco
Sunday, Dec. 7 | 6-8 p.m.
EV-mirnas predict outcomes in pediatric AML: A pilot study
Abdullah Alhumaid, Vivek Shastri, Zachary Greenberg, Jinmai Jiang, Raul Ribeiro, Jeffrey Rubnitz, Mei He, Thomas Schmittgen, Stanley Pounds, Jatinder Lamba
Sunday, Dec. 7 | 6-8 p.m.
Novel AML specific splice junction evaluation identifies ubc and DMBT1 as top proteins of clinical and therapeutic relevance in pediatric Acute Myeloid Leukemia
Ryanne Mulligan, Alyssa Obermayer, Xiaotu Ma, Paulo Rodriguez, Stanley Pounds, Rhonda Ries, Soheil Meshinchi, Timothy Shaw, Jatinder Lamba
Sunday, Dec. 7 | 6-8 p.m.
A patient-derived CRISPR platform reveals selective dependencies in Acute Myeloid Leukemia
Aneesha Nath, Nam Nguyen, Abderrahmane Tagmount, Nathan Seligson, Christopher Vulpe, Vivek Shastri, Dina Khalaf, Christopher Cogle, Stanley Pounds, Jatinder Lamba
Sunday, Dec. 7 | 6-8 p.m.
Interim Results of the CMML scrna-seq atlas: GMP skewing is independently associated with overall survival in CMML
Amy McLemore, Surendra Neupane, Zena Komrokji, Maria Balasis, Traci Kruer, Umesh Padia, Sean Murphy, Aline Renneville, Nathalie Droin, Dorothée Selimoglu-Buet, Miguel Martinez, chaomei Zhang, Tania Mesa, Sean Yoder, David Sallman, Andrew Kuykendall, Christopher Ryder1, Rami Komrokji, Mrinal Patnaik, Meghan Ferrall-Fairbanks, Regina Barzilay, Eric Solary, Eric Padron
Sunday, Dec. 7 | 6-8 p.m.
Comparison of infections in patients with chronic lymphocytic leukemia (CLL) treated with BTKi versus venetoclax obinutuzumab in first line therapy
Jawria Tufail, Zubair Hassan Bodla, Matthew Cortese, Muhammad Junaid Tariq
Sunday, Dec. 7 | 6-8 p.m.
NSD2 inhibition suppresses t(4;14) gene expression and oncogenic signaling to impair proliferation in multiple myeloma
Robert Chavez, Jonathan Patton, James Ackley, Mala Shanmugam, Constantine Mitsiades, Arun Wiita, Jonathan Licht, Erin Flynt, Terry Connolly, Karen Conneely, Sagar Lonial, Lawrence Boise, Benjamin Barwick
Sunday, Dec. 7 | 6-8 p.m.
Incidence, outcomes and economic burden of cytokine release syndrome and immune effector cell associated neurotoxicity syndrome in patients undergoing CAR-T cell therapy for multiple myeloma
Evani Jain, Anirudh Jain, Chiranjeevi Sainatham, Forat Lutfi
Sunday, Dec. 7 | 6-8 p.m.
The NLP protein is a novel regulator of G2-m Phase of the cell cycle critical for proliferation of human peripheral T-cell lymphomas
Julian Tobon, Dana Koptides, Jana Opavska, Viacheslav Morozov, Bayan Sabripour, David Veizaj, Jaclyn Shaw, Reem Abdelghany, Alexander Ishov, Rene Opavsky
Monday, Dec. 8 | 6-8 p.m.
Phase 1/1b dose escalation and expansion of CPX-351 in combination with gemtuzumab ozogamicin in newly diagnosed Acute Myeloid Leukemia (AML)
Onyee Chan, Kendra Sweet, Chetasi Talati, Fatima Tuz Zahra, Lisa Nardelli, Jatinder Lamba, Jongphil Kim, Jinming Song, Samuel Reynolds, Rory Shallis, Zhuoer Xie, Seongseok Yun, Andrew Kuykendall, Eric Padron, Alison Walker, Rami Komrokji, Jeffrey Lancet, David Sallman
Monday, Dec. 8 | 6-8 p.m.
Characteristics and therapies for pure red cell aplasia in patients with chronic lymphocytic leukemia (CLL) – a real world analysis from trinetx database
Jawria Tufail, Muhammad Junaid Tariq
Monday, Dec. 8 | 6-8 p.m.
Category: 700s – Transplantation and Adoptive Cell Therapies
Phase II Study of post transplant cyclophosphamide-based graft versus host disease prophylaxis after HLA-mismatched unrelated donor transplantation and reduced intensity conditioning: Results from the NMDP-sponsored access expansion Study
Mahasweta Gooptu, Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Erin Leckrone, Sarah Smith, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Farhad Khimani, Dipenkumar Modi, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez, Brian Shaffer
Sunday, Dec. 7 | 6-8 p.m.
Impact of graft versus host disease prophylaxis with post transplant cyclophosphamide on the prognostic value of HCT-CI
Ansh Mehta, Haesook Kim, Arcita Pramudita, Deborah Liney, Remy Dulery, Vincent Ho, Corey Cutler, John Koreth, Mahasweta Gooptu, Joseph Antin, Amar Kelkar, Sarah Nikiforow, Prashant Nageshwar, Catherine Wu, Jerome Ritz, Rizwan Romee, Robert Soiffer, Roman Shapiro
Sunday, Dec. 7 | 6-8 p.m.
Category: 800s – Gene Therapies, Chemical Biology, and Emerging Diagnostics
In silico structural biology studies inform the identification of “druggable” pockets in previously understudied dependencies with tumor type/lineage-selective roles
Evangelos Papadopoulos, Ricardo De Matos Simoes, Olga Dashevsky, Huihui Tang, Eleni Anastasakou, Vikas Gupta, Jonathan Licht, Benjamin Barwick, Lawrence Boise, Yuefang Deng, Aktas Bertal, Constantine Mitsiades
Saturday, Dec. 6 | 5:30-7:30 p.m.
Proteomics reveals COX7B as a prognostically relevant oxphos-linked protein in pediatric AML
Ryanne Mulligan, Ya Huang, Xueyuan Cao, Junmin Peng, Raul Ribeiro, Jeffrey Rubnitz, Stanley Pounds, Jatinder Lamba
Monday, Dec. 8 | 6-8 p.m.
Long-read whole genome sequencing improves clinical management in acute leukemia
Anna Lux, Francisco Marchi, Antonella Oettl, Petr Starostik, Dina Khalaf, Christopher Cogle, Stanley Pounds, Vivek Shastri, Jatinder Lamba
Monday, Dec. 8 | 6-8 p.m.
Category: 900s – Health Services, Quality Improvement, and Outcomes Research
Feasibility of collecting social determinants of health data in the frontline pediatric acute lymphoblastic leukemia (ALL) trial AALL1731: A report from the Children’s Oncology Group
Haley Newman, Morgan Paul, John Kairalla, Cindy Wang, Sunyu Kang, Sarah Alexander, Peter Cole, Iris Paltin, Colleen Kelly, Daniel Zheng, Rahela Aziz-Bose, Puja Umaretiya, Mignon Loh, Elizabeth Raetz, Stephen Hunger, Meenakshi Devidas, David Teachey, Rachel Rau, Sumit Gupta, Kira Bona
Saturday, Dec. 6 | 5:30-7:30 p.m.
Incidence burden of AML across the US and Puerto Rico: A two-decade analysis of trends and disparities (1999-2021)
Ummul Asfeen, Muzamil Khan, Waseem Nabi, Nouman Aziz, Swetha Balaji, Amara Sofia
Sunday, Dec. 7 | 6-8 p.m.
Disparate post-relapse survival outcomes by race/ethnicity for children with B-cell acute lymphoblastic leukemia: An analysis from the recall-1 study
Abigale Berry, Caitlin Elgarten, Yimei Li, Hongyan Liu, Katherine Lind, Daniel Zheng, Gabriella Nguyen, Vanessa Fabrizio, Maria Ortega, Jeremy Rubinstein, Troy Quigg, Anurekha Hall, Deepa Bhojwani, Nirali Shah, Shannon Maude, Sara Zarnegar-Lumley, Allison Weisnicht, Keri Toner, Molly Thornock, Stephanie Thomas, Nicholas Tastet, Heather Symons, Jamie Shoag, Amanda Saraf, April Rahrig, Mahvish Rahim, Alexandra Prosser-Dombrowski, Thomas Pfeiffer, Hiren Patel, Megan Murphy, Lindsey Murphy, Amy Moskop, Giselle Moore-Higgs, Jordan Milner, Kevin McNerney, Cathy Lee-Miller, Mira Kohorst, Hannah Kinoshita, Elizabeth Krieger, Smitha Vasanna, Alex Hoover, Ashley Hinson, Miza Salim Hammoud, Darcy Hamill, Erin Goode, Kelly Faulk, Alejandra Escobar Vasco, Lyannette Elo, Anna Elias, Elizabeth Eom, Jennifer Drinkwine, J. Gregory Dolan, Laurie Davis, Roland Chu, Eliza Briscoe, Deepika Bhatla, Jill Beck, Abdulla Al-Mulla, Ibrahim Ahmed, Lena Winestone, Regina Myers
Sunday, Dec. 7 | 6-8 p.m.
Toxicity and efficacy profile of cardioprotective vs conventional doxorubicin: A meta analysis
Evani Jain, Anirudh Jain, Chiranjeevi Sainatham, Omesh Prathiraja, Khalid Elhassan, Akash Khehra, Forat Lutfi
Monday, Dec. 8 | 6-8 p.m.
Survival after first relapse of pediatric B-ALL differs by insurance type: A real-world analysis from the recall-1 study
Katherine Lind, Abigale Berry, Yimei Li, Hongyan Liu, Jeremy Rubinstein, Gabriella Nguyen, Vanessa Fabrizio, Anurekha Hall, Deepa Bhojwani, Troy Quigg, Shannon Maude, Nirali Shah, Maria Ortega, Abdulla Al-Mulla, Ibrahim Ahmed, Jill Beck, Deepika Bhatla, Eliza Briscoe, Roland Chu, Laurie Davis, J. Gregory Dolan, Jennifer Drinkwine, Anna Elias, Lyannette Elo, Elizabeth Eom, Kelly Faulk, Erin Goode, Darcy Hamill, Miza Salim Hammoud, Ashley Hinson, Alex Hoover, Hannah Kinoshita, Mira Kohorst, Elizabeth Krieger, Cathy Lee-Miller, Kevin McNerney, Jordan Milner, Amy Moskop, Giselle Moore-Higgs, Lindsey Murphy, Megan Murphy, Hiren Patel, Thomas Pfeiffer, Alexandra Prosser-Dombrowski, Mahvish Rahim, April Rahrig, Amanda Saraf, Jamie Shoag, Heather Symons, Nicholas Tastet, Stephanie Thomas, Molly Thornock, Keri Toner, Smitha Vasanna, Alejandra Escobar Vasco, Allison Weisnicht, Sara Zarnegar-Lumley, Lena Winestone, Regina Myers, Caitlin Elgarten
Monday, Dec. 8 | 6-8 p.m.
Characterizing Hodgkin lymphoma survivors’ shared decision making across the care continuum
Raymond Mailhot Vega, M Devyn Mullis, Carla Fisher, Audrey Gardner, Jackie Causer3, Ed Michel, Robin Cacchio, Rashad Hayes, Emilie Lynch, Tricia Hernandez, Sharon Castellino, Erin Mobley
Monday, Dec. 8 | 6-8 p.m.
Category: Trials in Progress
A prospective, single site, single-arm pilot study of CPX-351 (Vyxeos) in individuals <22 years with secondary myeloid neoplasms
Alyssa Kennedy, Yonghui Ni, Stanley Pounds, Jatinder Lamba, Hiroto Inaba, Matthew Rees, Amr
Qudeimat, Emily Montgomery, Raul Ribeiro, Marcin Wlodarski
Saturday, Dec. 6 | 5:30-7:30 p.m.
Trainee Activities
Laboratory and Translational Hematology
Speaker: Olga Guryanova
Saturday, Dec. 8 | 11:15 a.m.
