April Publications

Recent publications from the UF Health Cancer Institute.

Cancer Control and Population Sciences

Wang Y, Li Y, Lin T, Guo Y. An operational target trial emulation framework for causal inference using electronic health record data. NPJ Digit Med. 2026 Apr 4. doi: 10.1038/s41746-026-02563-z. Online ahead of print. PubMed PMID: 41935211.

Zeidan RS, Shirali AS, Reinhard S, Picca A, Vial P, Pruinelli L, Garcia JGN, Leeuwenburgh C, Anton S. Inflammaging: From Mechanisms to Clinical Implications and Targeted Interventions. Aging Dis. 2026 Apr 24. doi: 10.14336/AD.2025.1557. Online ahead of print. PubMed PMID: 42065924.

Hu J, Hong YR, Xie Z. Palliative Care Awareness and Misconceptions By Sexual Orientation: HINTS 2018 and 2024. J Pain Symptom Manage. 2026 Apr 15:S0885-3924(26)00152-1. doi: 10.1016/j.jpainsymman.2026.04.004. Online ahead of print. PubMed PMID: 41997506.

Mobley EM, Ji L, Psihogios A, M Ingram K, Ghazal L, Nightingale CL, Dressler EV, Kittel C, Prasad PK, Freyer DR, Miller KA, Roth ME, Parsons SK, Beauchemin MP; Landscape Committee. Availability of cancer survivorship services for adolescents and young adults: Findings from the 2022 NCI Community Oncology Research Program Landscape Assessment. J Cancer Surviv. 2026 Apr 28. doi: 10.1007/s11764-026-02018-0. Online ahead of print. PubMed PMID: 42048009.

Monsour E, Ortiz Rocha A, Pathak A, Wu Y, Brito JP, Moser P, Singh Ospina NM. Evaluating the Completeness of Thyroid Nodule Ultrasound Reporting Using Natural Language Processing. Endocrine. 2026 Apr 27;91(1):145. doi: 10.1007/s12020-026-04594-8. No abstract available. PubMed PMID: 42043626.

Cousin L, Guillen S, Behar-Horenstein LS, Lyon DE. Effects of Psychosocial Interventions on Measures of Stress Among Breast Cancer Survivors: A Scoping Review. Cancer Nurs. 2026 Apr 13. doi: 10.1097/NCC.0000000000001550. Online ahead of print. PubMed PMID: 41984493.

Jones M, Hooks A, Stofer KA, Morand C, Yates H, Davis K, Worthen DL, O’Neal LJ. Social Networks Influence Vaccine Confidence in Rural Black Americans. Fam Community Health. 2026 Apr-Jun 01;49(2):90-100. doi: 10.1097/FCH.0000000000000449. Epub 2026 Feb 2. PubMed PMID: 41622538.

Chellian R, Huisman G, Bruijnzeel AW. Nicotine self-administration increases impulsive action: differential effects of nAChR modulators in a Go/No-Go task. bioRxiv [Preprint]. 2026 Apr 2:2026.03.31.715632. doi: 10.64898/2026.03.31.715632. PubMed PMID: 41959185; PubMed Central PMCID: PMC13060291.

Schutte SS, Ihnatsenka BV, Samouce CC, Chembrovich SV, Ruiz FJ, Zasimovich Y, Luria IT, Walker KK, Lizdas DE, Ahn JR, Lampotang S. Teaching Novices Ultrasound-Assisted Neuraxial Procedures Using Simulation-Based Courses: A Proof of Concept. J Educ Perioper Med. 2026 Apr 13;28(1):E765. doi: 10.46374/VolXXVIII_Issue1_Shutte. eCollection 2026 Jan-Mar. PubMed PMID: 41982269; PubMed Central PMCID: PMC13070746.

Bhasuran B, Prosperi M, Hanna K, Petrilli J, Washington CJ, He Z. Evaluation of causal reasoning for large language models in contextualized clinical scenarios of laboratory test interpretation. NPJ Digit Med. 2026 Apr 23. doi: 10.1038/s41746-026-02632-3. Online ahead of print. PubMed PMID: 42020503.

Bulusu R, Frimpong E, Okoro J, Krishnan S, Yoon S, Han B, Zhu X, Agyare E. Anti-EGFR liposomal drug delivery system loaded with AGY2 potentiates the anti-cancer effect of AGY2 against EGFR expressed pancreatic cancer. Int J Pharm X. 2026 Apr 15;11:100544. doi: 10.1016/j.ijpx.2026.100544. eCollection 2026 Jun. PubMed PMID: 42028057; PubMed Central PMCID: PMC13099476.

Chan JK, Rothe M, Garrett-Mayer E, Pisick E, Ghatalia P, Gregory A, deShazo M, Mileham KF, Murphy MC, Alese OB, Dib EG, Kohler PC, Moyers JT, Mangat PK, Hinshaw DC, Gregory A, Grantham GN, Halabi S, Schilsky RL. Pertuzumab and Trastuzumab in Patients With ERBB2/3-Altered Urothelial or Ovary/Fallopian Tube Cancer: Results From the Targeted Agent and Profiling Utilization Registry Study. JCO Precis Oncol. 2026 Apr;10(4):e2501250. doi: 10.1200/PO-25-01250. Epub 2026 Apr 30. PubMed PMID: 42060863.

Larios F, Borras-Osorio M, Wu Y, Claros AG, Toro-Tobon D, Cabezas E, Loor-Torres R, Chavez MM, Guevara Maldonado K, Andrango LV, Lizarazo Jimenez M, Alzamora IM, Al Zahidy M, Montero M, Proano AC, Jacome CS, Fan JW, Ponce-Ponte OJ, Branda ME, Singh Ospina N, Brito JP. Artificial Intelligence-Enabled Analysis of Radiology Reports: Epidemiology and Outcomes of Incidental Thyroid Findings. J Clin Endocrinol Metab. 2026 Apr 27:dgag186. doi: 10.1210/clinem/dgag186. Online ahead of print. PubMed PMID: 42037237.

Liang J, Kwak MJ, Shirvani M, Testa A, Samper-Ternent R, Xie Z, Tsai J. Latent class patterns of medication attitudes and their correlates among older adults in the United States. BMC Geriatr. 2026 Apr 23. doi: 10.1186/s12877-026-07546-z. Online ahead of print. No abstract available. PubMed PMID: 42026530.

Biederer J, Bergmann LL, Ackman JB, Hochhegger B, Azour L, Triphan SMF, Dinkel J, Ohno Y, Ozawa Y, van Beek EJR, Wucherpfennig L. MRI for Lung Cancer Management: Any Closer to Clinical Application? J Magn Reson Imaging. 2026 Apr 3. doi: 10.1002/jmri.70308. Online ahead of print. PubMed PMID: 41928658.

Peterson SL, Wang H, Miknevich MA, Piva SR, Cooper RA, Koontz AM. Feasibility and Preliminary Efficacy of Neuromuscular Electrical Stimulation in A Pilot Randomized Control Trial in Individuals With Transtibial Amputations. Am J Phys Med Rehabil. 2026 Apr 1;105(4):312-320. doi: 10.1097/PHM.0000000000002874. Epub 2025 Sep 29. PubMed PMID: 41082674.

Vieceli M, Park J, Saki M, Grewal H, Mendenhall NP, Johnson P, Artz M. Robust Four-Field and Arc LET-Optimized Proton Prostate Cancer Treatment Plans With Urethral Sparing. Int J Part Ther. 2026 Apr 17;20:101316. doi: 10.1016/j.ijpt.2026.101316. eCollection 2026 Jun. PubMed PMID: 42063694; PubMed Central PMCID: PMC13127624.

Wagner B, Braunstein S, Brisson R, De Leo A, Garda A, Gunther J, Henson C, Hirsch AE, Holmes J, Katz L, Mattes M, Schuster JM, Price J, Shiue K, Thomas H, Golden DW. EQual Rubric Evaluation of the Radiation Oncology Education Collaborative Study Group Entrustable Professional Activities. J Cancer Educ. 2026 Apr 24. doi: 10.1007/s13187-026-02881-6. Online ahead of print. No abstract available. PubMed PMID: 42032436.

Cancer Targeting and Therapeutics

Kabbej N, Sommerville JD, Gharaibeh RZ, Dang K, Atencio E, Rosenkrantz E, Day D, Ashby F, Naas T, Gauthier J, Newsome R, Jobin C, Quevedo A, MohamadZadeh M, Heldermon CD. Differences in composition and diversity of the gut microbiota of post-menopausal breast cancer patients. Sci Rep. 2026 Apr 9. doi: 10.1038/s41598-026-47558-8. Online ahead of print. No abstract available. PubMed PMID: 41957097.

Zhu X, Trindl CA, Li Q, Ye H, Alexander L, Huang D, Wei Y, Trieu V, Stansfield BN, Ooi A, Yang-Hartwich Y, Zhang DD, Chapman E. GRP78 Selective Inhibitors From a Direct-to-Biology Strategy. Angew Chem Int Ed Engl. 2026 Apr 23:e23960. doi: 10.1002/anie.202523960. Online ahead of print. PubMed PMID: 42023476.

Nickkholgh B, McGrath J, Sittadjody S, Chauhan J, Fletcher S, Balaji KC. Prostate cancer cells’ growth is decreased by novel MYC inhibitors. Invest New Drugs. 2026 Apr 28. doi: 10.1007/s10637-026-01613-3. Online ahead of print. PubMed PMID: 42047739.

Tong F, Seath CP. Proximity labeling tools for studying chromatin interactomes. Curr Opin Chem Biol. 2026 Apr 18;93:102686. doi: 10.1016/j.cbpa.2026.102686. Online ahead of print. PubMed PMID: 42001531.

Korntner S, Patel HA, Ebrahimiadib N. A Pediatric Case of Bilateral Congenital Vitreous Cysts of Non-Pigmented Ciliary Body Epithelium. J Vitreoretin Dis. 2026 Apr 9:24741264261435589. doi: 10.1177/24741264261435589. Online ahead of print. PubMed PMID: 41971247; PubMed Central PMCID: PMC13068782.

Tong J, Watkins JM, Burke JM, Kodadek T. Assessing the suitability of deubiquitylases as substrates for targeted protein degradation. Cell Chem Biol. 2026 Apr 16;33(4):571-581.e5. doi: 10.1016/j.chembiol.2026.03.009. Epub 2026 Apr 1. PubMed PMID: 41928511.

Tai Y, Li Y, Wang W, Lu Y, Qian Z, Conover M, Neu J, Denard C, Zheng Q, Pan J. Photothermal Recycling Biosensing for Continuous, Sensitive Molecular Quantification. bioRxiv [Preprint]. 2026 Apr 1:2026.03.30.714774. doi: 10.64898/2026.03.30.714774. PubMed PMID: 41958989; PubMed Central PMCID: PMC13060129.

Xu Z, Jolly KJ, Sankara CS, Mi K, Canchola A, Feng H, Gillen OP, Heiden KD, Basso KB, Chou WC, Lin Z, Zhang F. Engineering lipid nanoparticle surface hydrophobicity to modulate nano-bio interface and enable tissue-selective mRNA delivery. Biomaterials. 2026 Apr 16;334:124223. doi: 10.1016/j.biomaterials.2026.124223. Online ahead of print. PubMed PMID: 42085855.

Tong F, Ng HK, Seath CP. Design, Synthesis, and Application of Sulfonium Diazo Probes for Red-Light Photocatalytic Proximity Labeling. ACS Chem Biol. 2026 Apr 17. doi: 10.1021/acschembio.6c00025. Online ahead of print. PubMed PMID: 41994851.

Marshall EM, Zhu C, Mayhood L, Khalid Z, Yao H, Panieri G, Cediel-Becerra JDD, Chevrette MG, Strother JA, Loesgen S. Antinociceptive Benzothiazine and Benzothiazole Natural Products from Marine Croceibacter atlanticus. J Nat Prod. 2026 Apr 24;89(4):1265-1275. doi: 10.1021/acs.jnatprod.6c00098. Epub 2026 Apr 9. PubMed PMID: 41954290.

Shukla S, McGrath J, Willis R, Venkatesh A, Rodriguez Rosales RD, Kanumuambidi JP, Mietzsch M, McKenna R, Chardon-Robles J, Balaji KC. Protein Kinase D1 Translocates PARP1 to the Membrane and Is Associated With Increased Sensitivity to Cell Viability Inhibition by PARP1 Inhibitor Olaparib. Prostate. 2026 Apr 17. doi: 10.1002/pros.70182. Online ahead of print. PubMed PMID: 41995687.

Greenberg ZF, Hutchinson T, Kahn J, Graim KS, O’Malley P, He M. Urinary Extracellular Vesicles for High-Precision Bladder Cancer Subtyping and Prognosis. J Extracell Biol. 2026 Apr 30;5:e70141. doi: 10.1002/jex2.70141. eCollection 2026 May. PubMed PMID: 42077394; PubMed Central PMCID: PMC13132343.

Brummel BR, Kokkaliari S, Gao Q, Chen J, de Almeida LC, Tenneti S, Leas DA, Levit E, Alexander LS, Abboud KA, Wei P, Cameron MD, Rocca JR, Ratnayake R, Zhang DD, Luesch H, Huigens RW 3rd. Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer. Adv Sci (Weinh). 2026 Apr 30:e12849. doi: 10.1002/advs.202512849. Online ahead of print. PubMed PMID: 42059468.

Vieceli M, Park J, Saki M, Grewal H, Mendenhall NP, Johnson P, Artz M. Robust Four-Field and Arc LET-Optimized Proton Prostate Cancer Treatment Plans With Urethral Sparing. Int J Part Ther. 2026 Apr 17;20:101316. doi: 10.1016/j.ijpt.2026.101316. eCollection 2026 Jun. PubMed PMID: 42063694; PubMed Central PMCID: PMC13127624.

Wang Y, Li Y, Lin T, Guo Y. An operational target trial emulation framework for causal inference using electronic health record data. NPJ Digit Med. 2026 Apr 4. doi: 10.1038/s41746-026-02563-z. Online ahead of print. PubMed PMID: 41935211.

Zeidan RS, Shirali AS, Reinhard S, Picca A, Vial P, Pruinelli L, Garcia JGN, Leeuwenburgh C, Anton S. Inflammaging: From Mechanisms to Clinical Implications and Targeted Interventions. Aging Dis. 2026 Apr 24. doi: 10.14336/AD.2025.1557. Online ahead of print. PubMed PMID: 42065924.

Pisick E, Rothe M, Garrett-Mayer E, Srkalovic G, Chan JK, Calfa CJ, Leath CA 3rd, Marr AS, Gold PJ, Crane EK, Moyers JT, Yost Butler K, Gaba A, Thota R, Harnden KK, Alese OB, Jain A, Rueter J, Gill S, George TJ, Frimer M, Kayali F, Mangat PK, Hinshaw DC, Gregory A, Grantham GN, Halabi S, Schilsky RL. Temsirolimus in Patients With Solid Tumors With PIK3CA Mutations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study. JCO Precis Oncol. 2026 Apr;10(4):e2500985. doi: 10.1200/PO-25-00985. Epub 2026 Apr 22. PubMed PMID: 42018965.

Morse RT, Cao Y, Xu V, Weiss J, Sheth S, Patel S, Blumberg JM, Yarbrough WG, Lumley C, Hackman T, Patel S, Huff SB, Repka MC, Dagan R, Mendenhall W, Shen CJ, Chen XS, Chera BS. Sustained Locoregional Control With Deintensified Chemoradiotherapy for HPV Oropharyngeal Carcinoma. JAMA Otolaryngol Head Neck Surg. 2026 Apr 23:e260617. doi: 10.1001/jamaoto.2026.0617. Online ahead of print. PubMed PMID: 42024417; PubMed Central PMCID: PMC13107312.

Lee-Miller CA, Kairalla JA, Hibbitts E, Winick NJ, Rabin KR, Angiolillo A, Schore RJ, Salzer W, Burke MJ, Loh ML, Raetz EA, Hunger SP, Devidas M, Teachey DT, Gupta S, McNeer J. Adding Induction Intrathecal Cytarabine in Newly Diagnosed CNS2 B-Acute Lymphoblastic Leukemia Does Not Improve Outcomes. Blood Adv. 2026 Apr 15:bloodadvances.2026019660. doi: 10.1182/bloodadvances.2026019660. Online ahead of print. PubMed PMID: 41984995.

Ahmadi M, Zargar SJ, Alkaissi H, Ghayee HK, Pacak K, Jandaghi P, Auld D. BUB1 as a candidate non-oncogene addiction vulnerability in metastatic phaeochromocytoma/paraganglioma. Sci Rep. 2026 Apr 21. doi: 10.1038/s41598-026-49408-z. Online ahead of print. PubMed PMID: 42014906.

Verma M, Navarro V, Kosinski A, Taddei T, Kalman R, Barritt Iv AS, Jakab S, Serper M, Orman E, Balakrishnan M, Rakoski M, Rockey D, Hunt K, Cabrera R, Aytaman A, John B, Baffy G, Nathan R, Tapper E, Roytman M, McGuire B, Hoppmann N, Woodrell C, Bakitas M, Yue Y, Reeve B, Lin L, Tantala R, Volk M. Palliative Care Intervention for Patients With End-Stage Liver Disease: A Cluster Randomized Clinical Trial. JAMA Intern Med. 2026 Apr 13:e260571. doi: 10.1001/jamainternmed.2026.0571. Online ahead of print. PubMed PMID: 41973444; PubMed Central PMCID: PMC13077576.

Wang’ondu RW, Kairalla JA, Shago M, Angiolillo A, Breidenbach HM, Burke MJ, Carroll AJ, Rabin KR, Salzer W, Schore RJ, Wang C, Hunger SP, Teachey DT, Raetz EA, Loh ML, Davis KL, Rau RE. Chromosome 15q deletions confer inferior outcomes among children with ETV6::RUNX1 B-Cell Acute Lymphoblastic Leukemia. Blood Adv. 2026 Apr 15:bloodadvances.2026019599. doi: 10.1182/bloodadvances.2026019599. Online ahead of print. No abstract available. PubMed PMID: 41985005.

Nance-Richey R, Ackerman L, Ammons D, Chan AM, Stevenson V, Hery G, Hawkins I, Herrera A, Riva A, Zhang Y, Brown J, Dow SW, Maxwell EA, Bertran J, Aisa J, Takada M, Dark M, Saavedra PV, Milner RJ. Spatial transcriptomic mapping of canine osteosarcoma reveals immune microenvironment features linked to survival. Commun Biol. 2026 Apr 29. doi: 10.1038/s42003-026-10152-9. Online ahead of print. PubMed PMID: 42056464.

Alatawi H, Nair HH, Ai L, Mahmud I, Gour A, Singh A, Baek D, Yan B, Maharjan CK, Zhang W, Law BK, Zajac-Kaye M, Vulpe CD, Guryanova OA, Sharma AK, Garrett TJ, Sharma A, Heldermon CD, Hong S, Narayan S. CerS2 is a druggable target in triple-negative breast cancer. Mol Cancer Ther. 2026 Apr 21. doi: 10.1158/1535-7163.MCT-25-1159. Online ahead of print. PubMed PMID: 42012500.

Immuno-Oncology and Microbiome

Sayour EJ. Catching a chameleon. Science. 2026 Apr 2;392(6793):45. doi: 10.1126/science.aef9970. Epub 2026 Apr 2. PubMed PMID: 41926582.

Alatawi H, Nair HH, Ai L, Mahmud I, Gour A, Singh A, Baek D, Yan B, Maharjan CK, Zhang W, Law BK, Zajac-Kaye M, Vulpe CD, Guryanova OA, Sharma AK, Garrett TJ, Sharma A, Heldermon CD, Hong S, Narayan S. CerS2 is a druggable target in triple-negative breast cancer. Mol Cancer Ther. 2026 Apr 21. doi: 10.1158/1535-7163.MCT-25-1159. Online ahead of print. PubMed PMID: 42012500.

Nance-Richey R, Ackerman L, Ammons D, Chan AM, Stevenson V, Hery G, Hawkins I, Herrera A, Riva A, Zhang Y, Brown J, Dow SW, Maxwell EA, Bertran J, Aisa J, Takada M, Dark M, Saavedra PV, Milner RJ. Spatial transcriptomic mapping of canine osteosarcoma reveals immune microenvironment features linked to survival. Commun Biol. 2026 Apr 29. doi: 10.1038/s42003-026-10152-9. Online ahead of print. PubMed PMID: 42056464.

Alatawi H, Nair HH, Raza A, Velez E, Sharma AK, Narayan S. Human-Centric Modeling in Metastatic Breast Cancer: Organoids, Organ-on-Chip Systems, and New Approach Methodologies in the Post-FDA Modernization Act 2.0 Era. Cancers (Basel). 2026 Apr 4;18(7):1166. doi: 10.3390/cancers18071166. PubMed PMID: 41976388; PubMed Central PMCID: PMC13072243.

Ahn S, Fu W, van Gerwen M, Liu L, Li Z. A multi-omics framework for survival mediation analysis of high-dimensional proteogenomic data. PLoS Comput Biol. 2026 Apr 27;22(4):e1014217. doi: 10.1371/journal.pcbi.1014217. eCollection 2026 Apr. PubMed PMID: 42044175; PubMed Central PMCID: PMC13138757.

Still MEH, Burke J, Robblee J, Ranjan S, Galvez-Jimenez N, Moor RSF, Sharma A, Yogendran L, Siegel C, Lu-Emerson C, Karam M, Dhawan A, Budhu JA, Coffee E, Dunbar EM, Leung D, Schiff D, Peters KB, Ghiaseddin AP. Practical Management of Headaches in Patients With Primary and Secondary Brain Tumors. J Pain Symptom Manage. 2026 Apr 7:S0885-3924(26)00143-0. doi: 10.1016/j.jpainsymman.2026.03.017. Online ahead of print. PubMed PMID: 41956304.

Tushoski-Aleman GW, Rosales SA, Thompson GR, McKean JA, Pilecki M, Han S, Hughes SJ. The Rising Burden of Premature Mortality Due to Pancreatic Cancer in the United States. Pancreas. 2026 Apr 8. doi: 10.1097/MPA.0000000000002653. Online ahead of print. PubMed PMID: 41949055.

Takehara KK, Monell A, Luna V, Melisso B, Mempel KM, Cheung KP, Zane N, Challita PP, Ferry A, Xu EC, Olivari V, Scharping NE, Galletti G, Quon S, Ishibashi JR, Estep N, Johanneson JB, Pandya C, Anover-Sombke SD, McKay RR, Skene PJ, Pipkin ME, Heeg M, Reina-Campos M, Goldrath AW. Distinct tissue niches contribute to prostate tissue-resident memory CD8+ T cell differentiation and heterogeneity. Immunity. 2026 Apr 1:S1074-7613(26)00114-7. doi: 10.1016/j.immuni.2026.03.003. Online ahead of print. PubMed PMID: 41928518.

Jian Q, Chaudhry NA, Du F, Zimmermann E, Jiao T. Immunomodulators, Biologics, and 5-ASA for Inflammatory Bowel Disease and Major Adverse Cardiovascular Events in Older Adults. JAMA Netw Open. 2026 Apr 1;9(4):e269091. doi: 10.1001/jamanetworkopen.2026.9091. PubMed PMID: 42054028; PubMed Central PMCID: PMC13129880.

Kabbej N, Sommerville JD, Gharaibeh RZ, Dang K, Atencio E, Rosenkrantz E, Day D, Ashby F, Naas T, Gauthier J, Newsome R, Jobin C, Quevedo A, MohamadZadeh M, Heldermon CD. Differences in composition and diversity of the gut microbiota of post-menopausal breast cancer patients. Sci Rep. 2026 Apr 9. doi: 10.1038/s41598-026-47558-8. Online ahead of print. No abstract available. PubMed PMID: 41957097.

Levy E, Elliott L, Miller MA, Kramer M. Prolonged Survival With Homozygous Deletion of Exon 9 in Perlman Syndrome: A Case Report. Case Rep Genet. 2026 Apr 25;2026:9916711. doi: 10.1155/crig/9916711. eCollection 2026. PubMed PMID: 42040973; PubMed Central PMCID: PMC13109714.

Mechanisms of Oncogenesis

McMahon S, Jain V, Morozov V, Sethuraman S, Hu J, Shekhar R, Keil N, Turner P, Ishov A, Renne R. Non-canonical histone H3.3 and its chaperones HIRA and DAXX participate in the regulation of KSHV latency. bioRxiv [Preprint]. 2026 Apr 7:2026.04.02.716100. doi: 10.64898/2026.04.02.716100. PubMed PMID: 41993451; PubMed Central PMCID: PMC13081943.

Mahmud I, Pinto FG, Garrett TJ. Rapid Noninvasive Classification of Prostatic Disease Using Paper Spray Ionization Mass Spectrometry (PSI-MS)-Based Nontargeted Metabolomics. Anal Chem. 2026 Apr 29. doi: 10.1021/acs.analchem.6c00795. Online ahead of print. PubMed PMID: 42054656.

Nguyen LT, Rakestraw NR, Pizzano BLM, Iyyappan R, Young CB, Huang Y, Beerensson KT, Fang A, Antal SG, Anamisis KV, Peggs CMD, Yan J, Jing Y, Lewis JG, Burdine RD, Adamson B, Jiang Z, Toettcher JE, Myhrvold C, Jain PK. Efficient genome editing with chimeric oligonucleotide-directed editing. Nat Commun. 2026 Apr 13. doi: 10.1038/s41467-026-71624-4. Online ahead of print. PubMed PMID: 41968146.

Liang J, Zhou M, Xie M, Song Q. ShapeRNA: an integrated web server for RNA secondary structure, ensemble, and functional analysis. Nucleic Acids Res. 2026 Apr 23:gkag387. doi: 10.1093/nar/gkag387. Online ahead of print. PubMed PMID: 42023506.

Tang F, Liang X, Porter DF, Miao W, Maehlmann K, Yuan J, Khavari PA, Wang Y. Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells. Anal Chem. 2026 Apr 28;98(16):12090-12098. doi: 10.1021/acs.analchem.6c00902. Epub 2026 Apr 17. PubMed PMID: 41996289.

Prudent R, Ray AP, Thakur N, Moreno A, Tandaric T, Kanonenberg K, Lemoine H, Forcellini E, Cecon E, Roche D, Jockers R, Gutierrez-de-Teran H, Eddy MT. An Integrative Biophysical and Computational Workflow Uncovers New Allosteric Sites and Modulators of the Human A2A Adenosine Receptor. ACS Chem Biol. 2026 Apr 10. doi: 10.1021/acschembio.6c00003. Online ahead of print. PubMed PMID: 41961997.

Zhu X, Trindl CA, Li Q, Ye H, Alexander L, Huang D, Wei Y, Trieu V, Stansfield BN, Ooi A, Yang-Hartwich Y, Zhang DD, Chapman E. GRP78 Selective Inhibitors From a Direct-to-Biology Strategy. Angew Chem Int Ed Engl. 2026 Apr 23:e23960. doi: 10.1002/anie.202523960. Online ahead of print. PubMed PMID: 42023476.

Brummel BR, Kokkaliari S, Gao Q, Chen J, de Almeida LC, Tenneti S, Leas DA, Levit E, Alexander LS, Abboud KA, Wei P, Cameron MD, Rocca JR, Ratnayake R, Zhang DD, Luesch H, Huigens RW 3rd. Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer. Adv Sci (Weinh). 2026 Apr 30:e12849. doi: 10.1002/advs.202512849. Online ahead of print. PubMed PMID: 42059468.

Zhang Z, Liu Y, Wang S, Ma Q, Song Q, Bian J. GatorST: A Versatile Contrastive Meta-Learning Framework for Spatial Transcriptomic Data Analysis. Small Methods. 2026 Apr 8:e00006. doi: 10.1002/smtd.202600006. Online ahead of print. PubMed PMID: 41947710.

Omran K, Kousar I, Lu J, Tan M. B7-H3 (CD276) in exosome biogenesis and the tumor microenvironment: a new therapeutic nexus. Cell Commun Signal. 2026 Apr 11. doi: 10.1186/s12964-026-02872-6. Online ahead of print. PubMed PMID: 41964005.

Alatawi H, Nair HH, Ai L, Mahmud I, Gour A, Singh A, Baek D, Yan B, Maharjan CK, Zhang W, Law BK, Zajac-Kaye M, Vulpe CD, Guryanova OA, Sharma AK, Garrett TJ, Sharma A, Heldermon CD, Hong S, Narayan S. CerS2 is a druggable target in triple-negative breast cancer. Mol Cancer Ther. 2026 Apr 21. doi: 10.1158/1535-7163.MCT-25-1159. Online ahead of print. PubMed PMID: 42012500.

Alvarez G, Sebastian E, Mondal A, Roth MJ, Montelione GT, Perez A. Loop Plasticity Drives Paralog-Specific Recognition in BET ET Domains. J Chem Inf Model. 2026 Apr 27;66(8):4685-4695. doi: 10.1021/acs.jcim.6c00121. Epub 2026 Apr 15. PubMed PMID: 41983650.

Pain E, Singh PK, Khan Y, Mears G, Yang X, Lynham S, Devlin PF, Rutherford T, Jones KL, Walker MC, Beesley P, Gentry MS, Williams RS. Metabolic targeting of pantothenate by medium chain fats in glioblastoma cells. BMC Cancer. 2026 Apr 7. doi: 10.1186/s12885-026-15909-3. Online ahead of print. No abstract available. PubMed PMID: 41942899.

Shukla S, McGrath J, Willis R, Venkatesh A, Rodriguez Rosales RD, Kanumuambidi JP, Mietzsch M, McKenna R, Chardon-Robles J, Balaji KC. Protein Kinase D1 Translocates PARP1 to the Membrane and Is Associated With Increased Sensitivity to Cell Viability Inhibition by PARP1 Inhibitor Olaparib. Prostate. 2026 Apr 17. doi: 10.1002/pros.70182. Online ahead of print. PubMed PMID: 41995687.

Greenberg ZF, Hutchinson T, Kahn J, Graim KS, O’Malley P He M. Urinary Extracellular Vesicles for High-Precision Bladder Cancer Subtyping and Prognosis. J Extracell Biol. 2026 Apr 30;5:e70141. doi: 10.1002/jex2.70141. eCollection 2026 May. PubMed PMID: 42077394; PubMed Central PMCID: PMC13132343.

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