Recent publications from the UF Health Cancer Institute.
Cancer Control and Population Sciences
Yoon HS, Shu XO, Wu J, Sanderson M, Wang X, Wen W, Courtney R, Yang JJ, Blot WJ, Zheng W, Cai Q. Circulating metabolite biomarkers associated with prostate cancer risk in Black Americans: findings from the Southern Community Cohort Study. Br J Cancer. 2026 Jun 27. doi: 10.1038/s41416-026-03520-z. Online ahead of print. PubMed PMID: 42373845.
Xie Z, Hong YR, Liang J, Akter J, Hu J, Fisher C, Wilkie D. Awareness and misconceptions of palliative care among paid, unpaid, and non-caregivers in the U.S. BMC Palliat Care. 2026 Jun 10. doi: 10.1186/s12904-026-02190-1. Online ahead of print. PubMed PMID: 42271366.
Armstrong A, Heng YJ, Sardella BR, Ratcliffe M, Rosner B, Tamimi RM, Yaghjyan L. Associations of alcohol use with expression of stromal markers in benign breast biopsy samples. Br J Cancer. 2026 Jun 11. doi: 10.1038/s41416-026-03481-3. Online ahead of print. PubMed PMID: 42277287.
Xie Z, Liang J, Patel B, Hong YR, Jacobs M. Advance Care Planning Documentation Completeness and End-of-Life Care: Trends and Associations Using HRS 2010-2022 Data. Am J Hosp Palliat Care. 2026 Jun 16:10499091261462061. doi: 10.1177/10499091261462061. Online ahead of print. PubMed PMID: 42302299.
Ramsey ML, Forsmark CE. Exocrine Pancreatic Insufficiency. JAMA. 2026 Jun 10. doi: 10.1001/jama.2026.5759. Online ahead of print. PubMed PMID: 42268629.
Wingard JR, Lee JH, Li D. Reply to: “Liberalized Diets During Neutropenia: Ongoing Uncertainty in Hematopoietic Stem-Cell Transplantation” and “Impact of Transplant Type on Infection Risk in Studies of Neutropenic Diets”. J Clin Oncol. 2026 Jun 1:JCO2600696. doi: 10.1200/JCO-26-00696. Online ahead of print. No abstract available. PubMed PMID: 42224639.
Kayal G, Ocampo Ramos JC, Dinwiddie LE, Baggett JM, Dawson RJ, Marquis H, Wehmeier SK, Ivashchenko O, Carter LM, Bolch WE, Kesner AL. MIRD Pamphlet No. 34, Part 2: Benchmarking of MIRDct Software for CT Organ Dose Estimation. J Nucl Med. 2026 Jun 18:jnumed.125.271501. doi: 10.2967/jnumed.125.271501. Online ahead of print. PubMed PMID: 42315308.
Letta S, Tefera M, Wilfong T, LeLaurin JH, Mkuu RS, Montague M, Bteddini D, Tolera A, Haile Mariam D, Nakkash R, al’Absi M, Salloum RG. Dual use of tobacco and khat in eastern Ethiopia: a qualitative study. Tob Control. 2026 Jun 22:tc-2025-059800. doi: 10.1136/tc-2025-059800. Online ahead of print. PubMed PMID: 42331606.
Figg JW, Mark J, Washington CJ, Fusco A, Cremer MA, Cohen SA, Quintin S, Pereira DB, Ghiaseddin AP. Emerging Perspectives on Adverse Childhood Experiences and Brain Cancer Immunotherapy. Cancers (Basel). 2026 Jun 9;18(12):1882. doi: 10.3390/cancers18121882. PubMed PMID: 42352417; PubMed Central PMCID: PMC13297074.
Jugl S, Perez-Vilar S, Galati S, Sandhu SK, Chen HK, Chang SH, Wang Y, Kurzbach T, Adkins L, Guo J, Wang Y, Winterstein AG, Goodin A. Effectiveness of THC-containing cannabis for inflammatory bowel disease: a systematic review. J Cannabis Res. 2026 Jun 3. doi: 10.1186/s42238-026-00456-2. Online ahead of print. PubMed PMID: 42231518.
George TJ, Lin T, Nassour I, Rogers SC, Jang T, Sahin I, Ramnaraign BH, Fabregas J, Hitchcock K, Liu G, Russell KB, Turk AA, Kayaleh O, Fan ZH, DeRemer DL, Thomas RM, Lee JH, Hughes SJ. Use of liposomal irinotecan with 5-FU and oxaliplatin (NALIRIFOX) in neoadjuvant pancreatic adenocarcinoma: NEO-Nal-IRI trial. Oncologist. 2026 Jun 29:oyag250. doi: 10.1093/oncolo/oyag250. Online ahead of print. PubMed PMID: 42371783.
Visser O, Singhal N, Katta M, Pinsky E, Datta S, Singhal A. Unpacking X (formerly Twitter) discourse on fluoride and related topics during the 2024 US presidential election. J Am Dent Assoc. 2026 Jun 1:S0002-8177(26)00165-0. doi: 10.1016/j.adaj.2026.03.007. Online ahead of print. PubMed PMID: 42223388.
Alpert JM, Amin TB, Ali HM, Sainatham C, Javed MJ, Markham MJ, Bylund CL. Evaluation of a web-based educational tool for patients with cancer to improve digital communication quality: A pre-post study of the SEND application. Patient Educ Couns. 2026 Jun 11;150:109742. doi: 10.1016/j.pec.2026.109742. Online ahead of print. PubMed PMID: 42302498.
Mascarenhas E, Gelatti ACZ, Montella T, Corassa M, William WN Jr, Yamamura R, Baldotto C, Cronemberger EH, Calabrich AFC, Borges GS, Teixeira CHA, Matias D, Fares AF, Sampaio CDAT, Gazola AA, Zuanazzi FC, Schulze PAC, Franche LMT, de Jesus RG, Giacomazzi J, Rocha MS, Gossling G, Ferreira CG. Treatment of ALK+ Non-Small Cell Lung Cancer in the Brazilian Public and Private Health Care Systems: A Tale of Inequalities (LACOG/GBOT 1918). JCO Glob Oncol. 2026 Jun;12(6):e2600042. doi: 10.1200/GO-26-00042. Epub 2026 Jun 24. PubMed PMID: 42341249.
Olson LT, Sussman L, Moakley M, Poehler D, Allaire B, Roussos-Ross K, Hall JM. Tobacco Cessation Treatment in Pregnancy: Insights from Florida Medicaid Claims Data. Nicotine Tob Res. 2026 Jun 29:ntag140. doi: 10.1093/ntr/ntag140. Online ahead of print. PubMed PMID: 42372077.
Yao S, Liu J, Dalisay F, Johnson BK, Niederdeppe J. Cervical Cancer Information Seeking in the Digital Communication Environment. J Health Commun. 2026 Jun 15:1-11. doi: 10.1080/10810730.2026.2689090. Online ahead of print. PubMed PMID: 42290587.
Benites C, Chacko K, Chidarala S, Dziegielewski P. Maxillofacial Re-Reconstruction of Bony Free Flaps Affected by Osteoradionecrosis: 10-Year Single-Institution Experience. Head Neck. 2026 Jun 24. doi: 10.1002/hed.70364. Online ahead of print. PubMed PMID: 42340074.
Dove A, Bennion P, Jean-Baptiste S, Kirschner AN, Koneru B, Kluwe C, Newman N, Paul TM, Pearlstein K, Sharifzade-Moghaddam YH, Scarcella N, Schaaf SM, Tendulkar R, Russo S. Executive Summary of the American Radium Society (ARS) Appropriate Use Criteria (AUC) for the Use of Radiation in the Prevention and Treatment of Heterotopic Ossification (HO). Am J Clin Oncol. 2026 Jun 26. doi: 10.1097/COC.0000000000001345. Online ahead of print. PubMed PMID: 42357986.
Cancer Targeting and Therapeutics
Saeed A, Yothers G, Puhalla SL, Tojjari A, Rastogi P, Freeman TJ, Mathias MD, Seebach FA, Wolmark N, George TJ. EMPIRE (NSABP FC-13): a biomarker-driven phase II platform trial evaluating cemiplimab-based immunotherapy in microsatellite-stable colorectal cancer with ctDNA-defined minimal residual disease. Future Oncol. 2026 Jun 25:1-9. doi: 10.1080/14796694.2026.2688569. Online ahead of print. PubMed PMID: 42345857.
George TJ, Lin T, Nassour I, Rogers SC, Jang T, Sahin I, Ramnaraign BH, Fabregas J, Hitchcock K, Liu G, Russell KB, Turk AA, Kayaleh O, Fan ZH, DeRemer DL, Thomas RM, Lee JH, Hughes SJ. Use of liposomal irinotecan with 5-FU and oxaliplatin (NALIRIFOX) in neoadjuvant pancreatic adenocarcinoma: NEO-Nal-IRI trial. Oncologist. 2026 Jun 29:oyag250. doi: 10.1093/oncolo/oyag250. Online ahead of print. PubMed PMID: 42371783.
Alkaissi H, Taieb D, Ghayee HK. Pheochromocytomas and Paragangliomas. Endocrinol Metab Clin North Am. 2026 Jun;55(2):317-344. doi: 10.1016/j.ecl.2026.01.007. Epub 2026 Mar 13. PubMed PMID: 42067273; PubMed Central PMCID: PMC13313079.
Petit B, Michrafy I, Nafie J, Dyer GE, Marshall EM, Riquelme C, Cabrera-Pardo JR, Strother JA, Loesgen S. Anthracaurisin A horizontal line Discovery of a Cytotoxic Nor-Sesquiterpene Dimer from Patagonian Anthracophyllum discolor. J Nat Prod. 2026 Jun 26;89(6):1995-2007. doi: 10.1021/acs.jnatprod.6c00531. Epub 2026 Jun 11. PubMed PMID: 42273985; PubMed Central PMCID: PMC13316986.
Ishiyama Y, Venkatesh A, McGrath J, Rosales RDR, Kanumuambidi JP, Bandyk M, Balaji KC. An integrated restricted mean survival time-based evaluation of efficacy, toxicity, and cost in first-line immunotherapy regimens for metastatic renal cell carcinoma. Urol Oncol. 2026 Jun;44(6):135-145. doi: 10.1016/j.urolonc.2026.03.009. Epub 2026 Apr 15. PubMed PMID: 41991383.
Alli AA, Bala N, Xu Y, Denslow ND, Ghayee HK. Targeted lipidomics between hPheo1 and SDHB KD cells reveal changes in bioactive lipids and PKC with polyamine pathway inhibition. Physiol Rep. 2026 Jun;14(11):e70894. doi: 10.14814/phy2.70894. PubMed PMID: 42249664; PubMed Central PMCID: PMC13241704.
Vijayakurup V, Feely M, Zajac-Kaye M. Protocol for region-specific tumor dissection and protein extraction from a pancreatic neuroendocrine tumor mouse model. STAR Protoc. 2026 Jun 19;7(3):104653. doi: 10.1016/j.xpro.2026.104653. Online ahead of print. PubMed PMID: 42319834; PubMed Central PMCID: PMC13312136.
Zarrinpar A, Orinion AF. From prediction to practice: artificial intelligence as an enabling layer in liver transplant care – reflections on ILTS 2025. Front Transplant. 2026 Jun 10;5:1879684. doi: 10.3389/frtra.2026.1879684. eCollection 2026. PubMed PMID: 42358620; PubMed Central PMCID: PMC13290762.
Dias M, Annamalai T, Otsuka Y, Leng S, Chapagain T, Ferdous S, Shumate J, Scampavia L, Spicer TP, Leng F. A high-throughput fluorescent DNA cleavage assay for discovering bacterial DNA gyrase poisons. Nucleic Acids Res. 2026 Jun 8;54(11):gkag610. doi: 10.1093/nar/gkag610. PubMed PMID: 42306948; PubMed Central PMCID: PMC13273308.
Handeland AH, Indelicato DJ, Engeseth GM, Fjaera LF, Grewal HS, Ytre-Hauge KS, Muren LP, Lassen-Ramshad Y, Henjum H, Stokkevag CH. Voxel-wise case-control analysis of dose, linear energy transfer and symptomatic brainstem necrosis in pediatric brain tumors treated with proton therapy. Int J Radiat Oncol Biol Phys. 2026 Jun 13:S0360-3016(26)00834-5. doi: 10.1016/j.ijrobp.2026.05.054. Online ahead of print. PubMed PMID: 42288289.
Ma X, Jin W, Lu Q, Sun RC, Chen L. Reference-informed spatial domain detection using weak supervision for spatial transcriptomics. Genome Res. 2026 Jun 22. doi: 10.1101/gr.281260.125. Online ahead of print. PubMed PMID: 42236081.
…Gibbs CP, Johan MP, Johnson L, Johnston A, Joo MW, Joyce D, Jung B, Jungels C, Jutte P, Jutte W, Jaaskelainen AS, Kaldas K, Kapanci B, Karaca MO, Kawai A, Kemp A, Khal AA, Khan Z, Khan ZA, Khaouam N, Kim HS, Klopper S, Kobayashi E, Kobayashi H, Kontogeorgakos V, Kotrych D, Krebbekx GGJ, Krishnamurthy AV, Kunisada T, Kyte R, Lacroix V, Lazarides A, Le Nail LR, Lee FY, Lee J, Lee M, Legosz P, Lehner B, Leithner A, Leone G, Letson D, Lewis VO, Li B, Liikanen H, Lin P, Linda Z, Lindsay S, Lozano Calderon S, Lutomia Lumbasi M, Macdonald J, Machado P, Majirija E, Malina M, Malyk R, Marais L, Mascard E, Mattei JC, McCullough L, McMahon S, Medellin Rincon MR, Mediavilla Santos L, Meijer D, Meijer JG, Miller B, Molloy A, Moriel Garcesco DJ, Morris CD, Morse-Sanyal A, Mottard S, Mthethwa PG, Munoz-Montecinos C, Murcia M, Muller M, Nakayama R, Narhari P, Nasar A, Nayak P, Neugebauer J, Nieminen J, Ntombela P, Nystrom L, O’Reilly-Harbidge S, O’Toole G, Ogura K, Oktayana MD, Oliveira V, Olivier A, Olson D, Olusunmade O, Omar M, Omran Hasan Y, Ortiz-Cruz EJ, Ozaki S, Ozaki T, Ozkan K, Pala E, Palmerini E, Panchwagh Y, Pang G, Papagelopoulos P, Papagelopoulos DP, Paraliticci G, Parizzia W, Parry M, Pate M, Peiro A, Perera J, Petersen MM, Phakathi O, Phimolsarnti R, Phiri T, Pinheiro R, Pinto Santander N, Ploegmakers J, Pollock R, Powell G, Prabowo Y, Pruthi M, Puhaindran M, Quirion J, Quirland C, Rabin E, Rachbauer A, Radhakrishnan S, Raja A, Rajalbandi R, Rajani R, Rajasekaran RB, Rajasekaran S, Rajkovic S, Ramirez MT, Ramkumar DB, Rankin KS, Ras El Abiad A, Rasappan K, Redl M, Rizzo A, Rose PS, Rosenberg A, Russell M, Salcedo Rodriguez G, Saleh A, Sambri A, Samy A, Sanchez-Maldonado M, Saputra RD, Scanferla R, Scharschmidt T, Schubert T, Scoccianti G, Segura F, Sellevold S, Shehadeh A, Shreemal B, Shumelinsky F, Siddiqi AM, Silveri C, Sinnaeve F, Smolle MA, Snyman F, Solomons M, Sommerville S, Sood SS, Spense ME, Spiegel C, Spiguel A, Staals EL, Stavropoulos NA, Steadman P, Stern S, Stevenson J, Stoppiello P, Stubbe C, Sullivan MH, Sundin N, Suntaxi Basantes FM, Szostakowski B, Szostakowski B, Tandon N, Tang X, Tepper S, Terrarossa B, Thippeswamy PB, Thorkildsen J, Tootsi K, Torner-Rubies F, Tosyali K, Traub F, Trent J, Triganjananun C, Trikoupis I, Trullols L, Tsagkozis P, Tsoi K, Tuntarattanapong P, Ulrich MN, Vainio VM, Valencia JD, van de Sande M, van der Geest I, van der Wal RJ, van Langevelde K, Velez R, Verbeke L, Verspoor FGM, Versteeg A, Vicatos G, Virk JS, Visgauss J, Vyrva O, Wafa H, Wan Faisham WI, Wang PQ, Wei R, Wennergren D, Werier J, Weschenfelder W, Williams N, Wunder J, Yildiz HY, Yonamine ES, Yonezawa H, Yousuf M, Zaghloul A, Zainul-Abidin S, Zamora T, Zuckerman L, Zumarraga JP, Ozger H. A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM). Bone Joint J. 2026 Jun 9;108-B:xxx. doi: 10.1302/0301-620X.108B.BJJ-2026-0394. PubMed PMID: 42261942.
Figg JW, Mark J, Washington CJ, Fusco A, Cremer MA, Cohen SA, Quintin S, Pereira DB, Ghiaseddin AP. Emerging Perspectives on Adverse Childhood Experiences and Brain Cancer Immunotherapy. Cancers (Basel). 2026 Jun 9;18(12):1882. doi: 10.3390/cancers18121882. PubMed PMID: 42352417; PubMed Central PMCID: PMC13297074.
Xu L, Sadanand A, Neczypor EW, Liu YT, Butler E, Moore K, Bowman F, Mazumder Y, Naranjo A, Chlenski A, Xiao X, Guo L, Cohn SL, Applebaum MA, Skapek SX. A Bayesian-Based Integrative Bioinformatics Analysis Nominates Oncogenic Drivers in Neuroblastoma. Clin Transl Sci. 2026 Jun;19(6):e70627. doi: 10.1111/cts.70627. PubMed PMID: 42272085; PubMed Central PMCID: PMC13253972.
Beauvais B, Rohokale R, Mamputu S, Lupu I, Guo Z, Balieu S. Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells. Chembiochem. 2026 Jun 15;27(11):e70428. doi: 10.1002/cbic.70428. PubMed PMID: 42287618; PubMed Central PMCID: PMC13264470.
Strojan P, Eisbruch A, Corry J, Nuyts S, de Graaf P, Kowalski LP, Beitler JJ, Ng SP, Mendenhall WM, Sreeram MP, Rao KN, Araujo ALD, Ferlito A. Non-Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy? Head Neck. 2026 Jun 22. doi: 10.1002/hed.70356. Online ahead of print. PubMed PMID: 42333037.
Immuno-Oncology and Microbiome
Von Roemeling CA, Doonan BP, Carpenter SL, Patel JA, Jobin GW, Yang C, Bhatia A, Trivedi V, Acevedo A, Elliott T, Archibald V, Speakman SM, Matich E, Mitchell DA. Improving Immune Checkpoint Blockade Efficacy in Melanoma Brain Metastases through Myddosomal inhibition with Emavusertib. Mol Cancer Ther. 2026 Jun 24. doi: 10.1158/1535-7163.MCT-25-0349. Online ahead of print. PubMed PMID: 42338303.
Figg JW, Mark J, Washington CJ, Fusco A, Cremer MA, Cohen SA, Quintin S, Pereira DB, Ghiaseddin AP. Emerging Perspectives on Adverse Childhood Experiences and Brain Cancer Immunotherapy. Cancers (Basel). 2026 Jun 9;18(12):1882. doi: 10.3390/cancers18121882. PubMed PMID: 42352417; PubMed Central PMCID: PMC13297074.
Figg JW, Love C, West I, Jin D, Engelbart M, Ware D, Bessey R, Flores CT. Myeloid-Derived Suppressor Cells: Function, Migration, and Therapeutic Opportunities in Glioblastoma. Cells. 2026 Jun 17;15(12):1099. doi: 10.3390/cells15121099. PubMed PMID: 42346126; PubMed Central PMCID: PMC13296615.
Kaur G, Logue J, Brazauskas R, Oloyede T, Abid MB, Ahmed S, Aljurf M, Banerjee R, Bashey A, Beitinjaneh AM, Callander NS, Castillo P, Dholaria B, Goldsmith SR, Hashmi S, Kharfan-Dabaja MA, Liu H, Mian H, Nishihori T, Rejeski K, Saad A, Slade MJ, Turtle CJ, Vogl DT, Williams KM, Wirk B, Pasquini MC, Moskop A, Akhtar OS, Hansen DK, Janakiram M. Prolonged Cytopenia After Idecabtagene Vicleucel for Multiple Myeloma is Associated with Poor Overall Survival. Transplant Cell Ther. 2026 Jun 16:S2666-6367(26)00490-2. doi: 10.1016/j.jtct.2026.06.021. Online ahead of print. PubMed PMID: 42302965.
George TJ, Lin T, Nassour I, Rogers SC, Jang T, Sahin I, Ramnaraign BH, Fabregas J, Hitchcock K, Liu G, Russell KB, Turk AA, Kayaleh O, Fan ZH, DeRemer DL, Thomas RM, Lee JH, Hughes SJ. Use of liposomal irinotecan with 5-FU and oxaliplatin (NALIRIFOX) in neoadjuvant pancreatic adenocarcinoma: NEO-Nal-IRI trial. Oncologist. 2026 Jun 29:oyag250. doi: 10.1093/oncolo/oyag250. Online ahead of print. PubMed PMID: 42371783.
Mechanisms of Oncogenesis
Ma X, Jin W, Lu Q, Sun RC, Chen L. Reference-informed spatial domain detection using weak supervision for spatial transcriptomics. Genome Res. 2026 Jun 22. doi: 10.1101/gr.281260.125. Online ahead of print. PubMed PMID: 42236081.
Stanifer ML. Subtype-specific functions of basal IFNlambdas. J Virol. 2026 Jun 23;100(6):e0175525. doi: 10.1128/jvi.01755-25. Epub 2026 Jun 2. PubMed PMID: 42227763; PubMed Central PMCID: PMC13288807.
Li N, Gao Q, Jia H, Xue G, Zhou Y, Wang S, Ma S, Hu B, Zhao Z, Su C, Liu Y, Xi W, Li Z, Zhang DD, Chu P, Sun Z, Fang D. SIRT2-mediated deacetylation activates USP22 catalytic function for PD-L1 protein stabilization and tumor immune escape. J Clin Invest. 2026 Jun 2:e198270. doi: 10.1172/JCI198270. Online ahead of print. PubMed PMID: 42228402.
Saxena AS, Baer CF. High rate of mutation and efficient removal by selection of structural variants from natural populations of Caenorhabditis elegans. Genome Biol Evol. 2026 Jun 24:evag145. doi: 10.1093/gbe/evag145. Online ahead of print. PubMed PMID: 42340057.
