July Publications » Cancer Institute » UF Health Cancer Institute

Recent publications from the UF Health Cancer Institute.

Cancer Control and Population Sciences

Mendenhall NP, Bryant CM, Katz AJ, Chen R, DeWees T, Hobkirk J, Bremer C, Grammel LW, Griggs C, Marckini R, Nelson R, Simons V, Odedina FT, Vapiwala N, Deville C Jr, Crisp AM, Morris CG. Can Engagement aid in design and accrual on Clinical Trials? Observations from COMPPARE – A Prospective Comparison of Outcomes with Proton and Photon Radiation in Prostate Cancer. Int J Radiat Oncol Biol Phys. 2026 Jul 29:S0360-3016(26)04063-0. doi: 10.1016/j.ijrobp.2026.07.021. Online ahead of print. PubMed PMID: 42526648.

Sykes J, Uribe Sanchez ED, Benito D, Danyluk A, Conrad DJ, Lam A, Lee JH, Dziegielewski PT. Prognostic value of the 5-Item Modified Frailty Index in elderly patients undergoing free flap reconstruction for head and neck cancer. Oral Oncol. 2026 Jul 30;181:108088. doi: 10.1016/j.oraloncology.2026.108088. Online ahead of print. PubMed PMID: 42531842.

Nahid NA, Petry NJ, Baye JF, Gray CF, Myers RA, Elwood EN, Harris EC, Chakraborty H, Volpi S, Rider R, Dexter PR, Peterson JF, Skaar TC, Parvataneni HK, Cavallari LH, Johnson JA; IGNITE Investigators. Hydrocodone vs Oxycodone and Postoperative Pain and Opioid Use in Joint Arthroplasty. JAMA Netw Open. 2026 Jul 1;9(7):e2623079. doi: 10.1001/jamanetworkopen.2026.23079. PubMed PMID: 42446879; PubMed Central PMCID: PMC13370303.

Lopez-Quintero C. Integrating human and nonhuman intelligence to reduce tobacco’s public-health burden. Curr Opin Psychiatry. 2026 Jul 1;39(4):314-320. doi: 10.1097/YCO.0000000000001096. Epub 2026 May 3. PubMed PMID: 42154481.

Chiang CW, Brock G, Schmidt S, Fillingim RB, Schmidt S, Wei YJ. Predictive Models for Time to First Opioid Use Disorder or Opioid Overdose Among Older Adults. J Gen Intern Med. 2026 Jul 16. doi: 10.1007/s11606-026-10628-8. Online ahead of print. PubMed PMID: 42463630.

Casey DL, Renfro LA, Wu Y, McCarten K, Pei Q, Milgrom SA, Belsky JA, Cho S, Keller FG, Punnett A, Hodgson DC, Hoppe BS, Kelly KM, Castellino SM. Patterns of presentation and outcomes in stage IV Hodgkin lymphoma: A report from the Children’s Oncology Group (COG) AHOD1331 trial. Br J Haematol. 2026 Jul 8:10.1111/bjh.70625. doi: 10.1111/bjh.70625. Online ahead of print. PubMed PMID: 42419755; PubMed Central PMCID: PMC13386275.

Bobic M, Dawson RJ, Beekman C, Atta R, Wehrenberg-Klee E, Paganetti H, Bolch WE, Bertolet A, Huesa-Berral C. A proof-of-concept study of sub-resolution hepatic vasculature modeling to assess dose heterogeneity in transarterial radioembolization. Phys Med Biol. 2026 Jul 17. doi: 10.1088/1361-6560/ae8ca0. Online ahead of print. PubMed PMID: 42468568.

Shin B, Yeom YS, Kim S, Choi C, Kim H, Jeong JH, Bolch WE, Kim CH. Fetus-specific hematopoietic stem cell dosimetry framework for leukemia-relevant target cells during prenatal development. Phys Med Biol. 2026 Jul 22;71(14). doi: 10.1088/1361-6560/ae85ae. PubMed PMID: 42392152.

Pather K, Naser AR, Mobley EM, Garcia E, Elsheikh E, Cicali EJ, Crisp A, Cavallari LH, Sacco JM, Puri R. One PPI may not fit all-prevalence of CYP2C19 phenotypes in patients with Barrett’s esophagus. Surg Endosc. 2026 Jul 30. doi: 10.1007/s00464-026-13215-4. Online ahead of print. PubMed PMID: 42533164.

Underwood PW, Dillhoff M. Robotic Surgery for Pancreas Cancer. Surg Oncol Clin N Am. 2026 Jul;35(3):543-559. doi: 10.1016/j.soc.2025.12.015. Epub 2026 Apr 10. PubMed PMID: 42264697.

Tohme S, Bteddini D, Romani M, Kabakian-Khasholian T, El Kadi L, Abla R, El Ashkar C, Montague M, Theis R, Khaywa J, Osman MH, Ward K, Shelley DR, Nakkash R, Salloum RG, LeLaurin JH. Patient perspectives to inform the implementation of tobacco use treatment in Lebanon’s safety net primary care system: a qualitative study. BMJ Open. 2026 Jul 6;16(7):e115035. doi: 10.1136/bmjopen-2025-115035. PubMed PMID: 42409400; PubMed Central PMCID: PMC13343104.

Reuter K, Freyer DR, Milam J, Mobley EM. Inconsistent reporting of adolescent and young adult (AYA) status in non-interventional cancer research: a critical barrier to evidence usability. BMJ Open. 2026 Jul 29;16(7):e107742. doi: 10.1136/bmjopen-2025-107742. PubMed PMID: 42526924; PubMed Central PMCID: PMC13422801.

Cancer Targeting and Therapeutics

Duckett SM, Ducharme JB, Schonk MM, Neyroud D, Judge SM, Judge AR. Murine pancreatic tumors induce pathological remodeling of muscles critical to chewing and swallowing. Am J Physiol Cell Physiol. 2026 Jul 29. doi: 10.1152/ajpcell.00390.2026. Online ahead of print. PubMed PMID: 42526053.

McGrath J, Willis R, Balaji S, Ishiyama Y, Sceats H, Bandyk M, Balaji KC. Lutetium-177-PSMA radioligand therapy in metastatic hormone-sensitive prostate cancer: A systematic review of efficacy, safety, and combination strategies. Urol Oncol. 2026 Jul 18:S1078-1439(26)00585-5. doi: 10.1016/j.urolonc.2026.06.028. Online ahead of print. PubMed PMID: 42471290.

McGrath J, Banerjee I, Ishiyama Y, Balaji KC. Network meta-analysis of immune checkpoint inhibitors in BCG-naive, high-risk non-muscle-invasive bladder cancer. Urol Oncol. 2026 Jul 14:S1078-1439(26)00565-X. doi: 10.1016/j.urolonc.2026.06.007. Online ahead of print. PubMed PMID: 42448544.

Rocha Lima CMSP, Yothers G, George TJ, Hochster HS, Sanoff HK, Cohen DJ, Guthrie KA, Jacobs SA, Saeed A, Kopetz S, Colangelo LH, Freeman TJ, Cole SW, Khalil M, Devanna S, Zuckerman DS, Hong TS, Henry NL, Ganz PA, Blanke CD, Wolmark N, Overman MJ. COMMIT: A Randomized Study of mFOLFOX6/Bevacizumab/Atezolizumab or Atezolizumab Alone as First-Line Treatment of Deficient DNA Mismatch Repair Metastatic Colorectal Cancer. J Clin Oncol. 2026 Jul 29:JCO2503052. doi: 10.1200/JCO-25-03052. Online ahead of print. PubMed PMID: 42525921.

Maisano D, Wang T, Kulp SB, Favasuli VK, Tong Y, Cumerlato M, Li C, Barello F, Turi M, Rampa P, Parisi RA, Garbicz F, Ladisa F, Giorgetti G, Chakraborty C, Vreux L, Sangiorgio V, Sarotto I, Aktas Samur A, Samur MK, Carrasco RD, Fulciniti M, Cameron MD, Anderson KC, Gulla A, Childs-Disney J, Disney MD, Morelli E, Munshi NC. A first-in-class RNA degrader reduces c-MYC expression and myeloma cell survival in preclinical models. Blood. 2026 Jul 29:blood.2026033241. doi: 10.1182/blood.2026033241. Online ahead of print. PubMed PMID: 42526890.

Maharjan CK, Liu Y, Xiao Y, Podder BR, Montgomery TH, Wang L, Kim MC, Jin Z, Anvar S, Tithi TI, Shastri VM, Stevens AM, Kolb R, Zhao C, Qian Z, Lamba JK, Zheng G, Zhang W. PROTAC-mediated targeting of IKKbeta and NR4A1 for AML therapy. Oncogene. 2026 Jul 30. doi: 10.1038/s41388-026-03925-3. Online ahead of print. PubMed PMID: 42533114.

Hamid O, Forget F, Johnson M, George TJ, Bourayou N, Ioannidis S, Zhou F, Yang H, Dong Z, Gutierrez ME. Phase 1/2 study of INCAGN01876, an anti-GITR agonist monoclonal antibody, plus immunotherapy for advanced cancers. Oncologist. 2026 Jul 30:oyag257. doi: 10.1093/oncolo/oyag257. Online ahead of print. PubMed PMID: 42530885.

Ma X, Allison D, Macedo JKA, Bolton KE, Clarke H, Young LEA, Bian J, Neltner JH, Kooi CV, Sun RC, Gentry MS, Chen L. Machine-Learning-Based Prediction of Clinical Outcomes in Gliomas Using Glycomic Features. Comput Struct Biotechnol J. 2026 Jul 9;35(1):0153. doi: 10.34133/csbj.0153. eCollection 2026. PubMed PMID: 42428521; PubMed Central PMCID: PMC13346664.

Davini M, Naranjo A, Chen L, Bagatell R, DuBois SG, Irwin MS, Goldsmith KC, Hogarty MD, Matthay KK. Factors Impacting Overall Survival Post-Relapse in High-Risk Neuroblastoma: Children’s Oncology Group Outcomes From 2000 to 2019. Pediatr Blood Cancer. 2026 Jul 23:e70520. doi: 10.1002/1545-5017.70520. Online ahead of print. PubMed PMID: 42487567.

Sokol E, Naranjo A, Chen L, Mody R, DuBois SG, Bagatell R, Pinto N. Long-Term Outcomes of Patients With Relapsed/Refractory Neuroblastoma Treated on ANBL1221: A Report From the Children’s Oncology Group. Pediatr Blood Cancer. 2026 Jul 23:e70504. doi: 10.1002/1545-5017.70504. Online ahead of print. PubMed PMID: 42487540.

Arora RS, Davidson A, Gonzalez G, Indelicato DJ, Kebudi R, Lam CG, McLoone J, Mendez A, Moreno F, Qureshi BM, Schoeman J, Weber LS, Slone JS, Vasquez L, Chantada GL; International Society of Paediatric Oncology (SIOP). SIOP Standards Framework for Pediatric Oncology Units in Low- and Middle-Income Countries. Pediatr Blood Cancer. 2026 Jul 29:e70469. doi: 10.1002/1545-5017.70469. Online ahead of print. PubMed PMID: 42527961.

Swartz T, Cavazos JE, Horwitz M, Hu PJ, Sampson B, Scharschmidt T, Zarrinpar A, Mohr N, Mankoff D, Chu J, Rhee KY, Emala CW, Williams CS. Navigating the path: Advice to physician-scientists on choosing a clinical specialty. Elife. 2026 Jul 3;15:RP110448. doi: 10.7554/eLife.110448. PubMed PMID: 42397115; PubMed Central PMCID: PMC13331548.

Immuno-Oncology and Microenvironment

Newsome RC, Jobin C. Microbiota and immunotherapy: The birth of a new paradigm? Cell Metab. 2026 Jul 7;38(7):1269-1272. doi: 10.1016/j.cmet.2026.06.007. PubMed PMID: 42413478.

Schell BB, Solt L. A breath of fresh AIR in novel CAR T cell design. Sci Immunol. 2026 Jul 3;11(121):eaej9802. doi: 10.1126/sciimmunol.aej9802. Epub 2026 Jul 3. PubMed PMID: 42397933.

Mercado-Rodriguez C, Chitre S, Park PH, Yang Y, Pompetti A, Gharaibeh RZ, Brant JO, Issa JJ, Jobin C. Defined bacterial consortium highlights the impact of intestinal bacteria on DNA methylation and tumorigenesis. Genome Biol. 2026 Jul 7;27(1):217. doi: 10.1186/s13059-026-04183-y. PubMed PMID: 42415118; PubMed Central PMCID: PMC13343937.

Nozka A, Valdes DP, Imhoff ED, Melnyk A, Rinaldi-Ramos CM. Flash nanoprecipitation of magnetic particle imaging tracers with tunable performance. Nanoscale. 2026 Jul 7. doi: 10.1039/d6nr01104g. Online ahead of print. PubMed PMID: 42411402; PubMed Central PMCID: PMC13339030.

Valdes DP, Zammataro SN, Melnyk A, Velazquez-Albino AC, Ali SR, Rinaldi-Ramos CM. Systematic evaluation of magnetic particle imaging quantification strategies in biologically relevant scenarios using anatomically correct 3D printed mouse phantoms. Phys Med Biol. 2026 Jul 28. doi: 10.1088/1361-6560/ae91c7. Online ahead of print. PubMed PMID: 42520842.

Kumar S, Patterson FM, Conklin T, Hsu SJ, Meli V, Chan K, Allen KD, Liu WF, Sharma B. Controlled release of CD200 inhibits inflammatory macrophages and chondrocyte catabolism. NPJ Biomed Innov. 2026 Jul 29;3(1):44. doi: 10.1038/s44385-026-00101-w. PubMed PMID: 42527473; PubMed Central PMCID: PMC13421671.

Plitt T, Piessevaux A, Rajpal U, Fischer J, Spindler MP, Ruprecht C, Li Z, Mogno I, Yang Y, Desch AN, Chu G, Jiang Z, Wang J, Gevers D, Pocalyko D, Geis AL, Jobin C, Bachman KE, Sears CL, Britton GJ, San Mateo LR, Faith JJ. Combining genotoxic gut bacterial strains increases tumor burden and accelerates onset in a germ-free mouse model of colon carcinogenesis. Cell Rep. 2026 Jul 28;45(7):117645. doi: 10.1016/j.celrep.2026.117645. Epub 2026 Jul 7. PubMed PMID: 42412611.

Shi D, Li X, Chen Y, Chen Y, Song Q, Su J. Combining VEGFR tyrosine kinase inhibitors and PD-1/PD-L1 inhibitors versus VEGFR tyrosine kinase inhibitors monotherapy in renal cell carcinoma: a target trial emulation. medRxiv [Preprint]. 2026 Jul 15:2026.06.30.26356941. doi: 10.64898/2026.06.30.26356941. PubMed PMID: 42428070; PubMed Central PMCID: PMC13345448.

Mechanisms of Oncogenesis

Manzi MS, Phophi L, de Oca JMF, Wilt HM, Ensberg KJ, Feswick A, Karst SM, Tibbetts SA. Early-life gammaherpesvirus infection results in an expanded long-term latent reservoir. Front Cell Infect Microbiol. 2026 Jul 15;16:1874370. doi: 10.3389/fcimb.2026.1874370. eCollection 2026. PubMed PMID: 42528674; PubMed Central PMCID: PMC13414197.

Gutti JR, Clarke DM, Saba C, Nagata K. Incorporating Hypofractionated Radiotherapy Improves Management of Canine Urothelial Carcinoma: A Retrospective Study. Vet Radiol Ultrasound. 2026 Jul;67(4):e70196. doi: 10.1111/vru.70196. PubMed PMID: 42216724; PubMed Central PMCID: PMC13355133.

Wang Z, Baker TR, Malin AJ. Mechanisms of neurotoxicity of fluoride or aluminum: implications for neurodegenerative disease risk. Curr Res Toxicol. 2026 Jul 10;11:100313. doi: 10.1016/j.crtox.2026.100313. eCollection 2026. PubMed PMID: 42495713; PubMed Central PMCID: PMC13393744.