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Research Snapshots

The Cancer Center’s Research Snapshots highlight recent discoveries made by Cancer Center researchers.

Research Snapshots aim to make research discoveries in newly published manuscripts more accessible for other scientists and the community as a whole.

If you are a Cancer Center researcher and would like to have your research considered for this feature, please contact communications specialist Leah Buletti or research communications administrator Ian Bennett.

UF study finds younger patients with colorectal cancer less likely to have targetable genetic mutations

Researchers found that while younger patients with colorectal cancer were significantly more likely to be diagnosed with advanced stage colorectal malignancies, these patients had significantly lower rates of genetic mutations. That decreases the number of effective, approved drugs that are available for treatment. Universal genetic testing at UF Health identified a relatively large population of older patients with sporadic colorectal cancer who were eligible for immunotherapy, emphasizing the importance of testing all patients.

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A new way to capture cancer cells’ symphony

A team of UF researchers has shed new light on the functional mechanisms of spontaneous calcium waves in human color and prostate cancer cells. The study indicated that calcium dynamics enable long-distance functional communication in electrically non-excitable cancer cells.

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Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort

The functional relationship between immunity, intestinal microbiota and non-small cell lung cancer (NSCLC) response to immune checkpoint inhibitors (ICI) PD1 in an American cohort remains unexplored. In a new Genome Medicine study titled, “Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort…”

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