In the News
The Cancer Center’s Research Snapshots highlight recent discoveries made by Cancer Center researchers.
Research Snapshots aim to make research discoveries in newly published manuscripts more accessible for other scientists and the community as a whole.
If you are a Cancer Center researcher and would like to have your research considered for this feature, please contact communications specialist Leah Buletti.
Researchers found that while younger patients with colorectal cancer were significantly more likely to be diagnosed with advanced stage colorectal malignancies, these patients had significantly lower rates of genetic mutations. That decreases the number of effective, approved drugs that are available for treatment. Universal genetic testing at UF Health identified a relatively large population of older patients with sporadic colorectal cancer who were eligible for immunotherapy, emphasizing the importance of testing all patients.
A team of UF researchers has shed new light on the functional mechanisms of spontaneous calcium waves in human color and prostate cancer cells. The study indicated that calcium dynamics enable long-distance functional communication in electrically non-excitable cancer cells.
A team led by UF researchers has used genome-wide CRISPR/cas9 screening to identify genes that are sensitive or resistant to etoposide, a chemotherapy drug used to treat pediatric acute myeloid leukemia, or AML. The findings could pave the way for developing new drug targets to overcome treatment resistance.
An observational study of more than 77,000 postmenopausal women found no association between coffee consumption and overall invasive breast cancer risk or subtype-specific breast cancer risk.
A team of researchers led by UF Health Cancer Center members Xin Tang, Ph.D., and Dietmar Siemann, Ph.D., has developed an open-source software program to help researchers with user-programmable, multifunctional and automatic time-lapse live cell/tissue imaging.
A team of researchers led by UF Health Cancer Center member Xin Tang, Ph.D., has developed a new biophysics technique to shed light on the mechanobiology of the nucleus in single cancer and normal cells.
A group of researchers led by UF Health Cancer Center member Mei He, Ph.D., has developed a new exosome isolation approach that could have important implications for discovering and detecting cancer biomarkers.
The functional relationship between immunity, intestinal microbiota and non-small cell lung cancer (NSCLC) response to immune checkpoint inhibitors (ICI) PD1 in an American cohort remains unexplored. In a new Genome Medicine study titled, “Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort…”
Cancer and Alzheimer’s disease are common diseases in aging populations. According to prior research, there is a lower incidence of Alzheimer’s disease-type (amnestic) dementia among individuals with cancer. Both cancer and amnestic dementia are prevalent and potentially lethal clinical syndromes.
The UF Health Cancer Center was well represented at the ASCO GI Cancer Symposium that was held virtually and in-person in San Francisco, Calif., on Jan. 20-22, 2022. View Cancer Center member’s recorded virtual GI ASCO presentations.
Sexual harassment in the workplace of clinical oncologists remains to be fully characterized. In this study, Merry J. Markham, M.D., FACP, and Julia L. Close, M.D., and team conducted a prospective cross-sectional study of clinical oncologists in the United States.
A study published on February 3 shows how to create a social media identity, best practices for engaging both in patient and caregiver spaces and professional communities, and how to address inappropriate behavior on social media with the goal of helping physicians develop an enjoyable experience online.
A study published in The Journal of Nutrition has shown an inverse association of dietary intake of vitamin A, including carotenoids, with ER-positive breast cancer risks among premenopausal Black women.
miRNAs play key roles in a variety of biological processes and human diseases and several miRNA-targeted therapeutics have undergone clinical trials for treating human cancers.
Mingyi Xie’s, Ph.D., lab in the Department of Biochemistry and Molecular Biology, College of Medicine at the University of Florida studies RNA processing mechanisms that drive cancer development.