Cancer Control and Population Sciences Aims

The specific aims capitalize on advances in -omics, cancer biology, and cancer imaging to further the development, testing, and implementation of primary, secondary, and tertiary cancer prevention strategies in diverse populations:

  • Aim 1.  Elucidate Molecular, Behavioral, Social, Environmental, and Other Risk Factors in Cancer Incidence and Mortality.

Observational studies characterize risk factors relevant to the Catchment Area to better understand cancer incidence, progression, outcome, and mortality, and to inform intervention and policy.

  • Aim 2. Develop and Evaluate Primary and Secondary Cancer Prevention Interventions.

CCPS interventional research spans efficacy, effectiveness, and pragmatic trials that are designed to mitigate the impact of risk factors identified in Aim 1. Current interventions address relevant modifiable risk factors in the Catchment Area, particularly smoking tobacco, HPV vaccination, diet, and physical activity, as well as cancer screening among underserved populations. These studies are conducted in collaboration with COE and leverage UFHCC strengths in community-engaged research and innovative digital health interventions that can be scaled up to advance dissemination and implementation, and to generate the greatest community impact.

  • Aim 3. Address the Unique Needs of Cancer Survivors.

Using both observational and interventional study designs, survivorship research focuses on mitigating the progression and other sequelae of cancer in populations of cancer survivors. Current studies engage patient advocates and COE to address the impact of cancer treatment on a broad range of outcomes, including symptom burden, clinical trial enrollment, aging trajectories, and late effects.