Katelyn Bruno, Ph.D., FHFSA, FACC
Assistant Professor of Cardiovascular Medicine, Dept. of Medicine
As cancer survivorship increases, the effect of cancer therapies is leading to a new clinical problem for cancer patients- cardiotoxicity. Cancer therapy cardio-toxicity, or cardio-oncology, focuses on understanding the mechanisms behind why cancer therapies cause cardiac complications/conditions, determining who is at risk of cardio-toxicity, and how to prevent, treat, and reverse cardiac damage. Additionally, the newer aspect of the field of cardio-oncology is “reverse cardio-oncology”, the study of how cardiovascular risk factors or disease can increase the risk of cancer through overlapping mechanisms and risk factors. This presentation will review what cardio-oncology is, what is done clinically in a cardio-oncology clinic, and some of the research being conducted at UF and elsewhere to further increase cancer and cardiovascular disease survivorship.
Dr. Katelyn Bruno is an Assistant Professor of Cardiovascular Medicine and the Co-Chair of the UF Health Cancer Institute Cardio-Oncology Working Group. She is the Director of the Translational Cardio-Immunology Laboratory. She utilizes cell culture, mouse models, and human samples and data to study cardiomyopathies, focusing on myocarditis and cancer therapy cardio-toxicity.
Core Standards
SC.912.L.16.8
Explain the relationship between mutation, cell cycle, and uncontrolled cell growth potentially resulting in cancer.
SC.912.N.1.1
Define a problem based on a specific body of knowledge, for example: biology, chemistry, physics, and earth/space science, and do the following: Pose questions about the natural world, (Articulate the purpose of the investigation and identify the relevant scientific concepts), Conduct systematic observations, Examine books and other sources of information to see what is already known, Communicate results of scientific investigations, and Evaluate the merits of the explanations produced by others.
SC.912.N.1.3
Recognize that the strength or usefulness of a scientific claim is evaluated through scientific argumentation, which depends on critical and logical thinking, and the active consideration of alternative scientific explanations to explain the data presented.
SC.912.N.1.7
Recognize the role of creativity in constructing scientific questions, methods and explanations.
HE.912.PHC.1.1
Evaluate personal health practices and overall health status to include all dimensions of health.
