2023-2025 Cohort

The second cohort of pre-and postdoctoral trainees joined the TICaRT Program in August 2023. They will spend two years in the program, working as teams on joint projects.

Team Project: PROTAC-mediated Degradation of the Latency-Associated Nuclear Antigen (LANA) to Target KSHV Latency

Sarah McMahon, Ph.D. Postdoctoral Fellow
Mentor: Rolf Renne, Ph.D., Molecular Genetics & Microbiology
Research Project: Epigenetic regulation of KSHV latency


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Alexis Smith, Predoctoral Fellow
Mentor: Guangrong Zheng, Ph.D., Pharmaceutical Sciences-Medicinal Chemistry
Dissertation Project: Development of potent METTL3 PROTAC degraders for treatment of AML


Team Project: Utilizing proteolysis targeting chimeras against BCL-2 and BCL-X for clearing senescent cells to reverse therapy induced cachexia

Jeremy Ducharme, Ph.D., Postdoctoral Fellow
Mentor: Andrew Judge, Ph.D., Physical Therapy
Research Project: Development of Novel Therapeutics for Cancer Cachexia


Madison Carelock, Predoctoral Fellow
Mentor: Weizhou Zhang, Ph.D., Biomedical Sciences-Cancer Biology
Dissertation Project: Dissecting the lineage-specific role of BCL-XL in breast cancer metastasis


Team Project: Pancreatic Ductal Adenocarcinoma Biomarker Detection/Validation via Intelligent Microrobotic Chip Device

Nathan Hart, Predoctoral Fellow
Mentor: Yong Zeng, Ph.D., Analytical Chemistry
Dissertation Project: CRISPR-based Biosensing of Target MiRNAs Using Micro-scale Pneumatic Actuator


Jordan McKean, M.D., Postdoctoral Fellow
Mentor: Steven Hughes, M.D., General Surgery


Team Project: Optimizing lung cancer risk assessment: from bench to trench

Meghann Wheeler, Predoctoral Fellow
Mentor: Dejana Braithwaite, Ph.D., Epidemiology
Dissertation Project: Evaluating proteomic and metabolomic blood-based biomarkers for use in lung cancer risk assessment


Breanne Freeman, Predoctoral Fellow
Mentor: Chengguo Xing, Ph.D., Pharmaceutical Sciences-Medicinal Chemistry
Dissertation Project: Developing lung carcinogenesis biomarkers and cancer risk predictive
score on a tobacco smoke-induced lung carcinogenesis A/J mouse cohort


Publications

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