Protocol Summary

Protocol No.: OCR17545

Sponsor Protocol No.: ALTE16C1

Protocol Title.: Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors

Principal Investigator: Slayton, William

Objective: This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.

Description: Participants complete a health questionnaire over 30-45 minutes. Patients also provide saliva and semen samples and undergo collection of blood.

Phase: N/A

Age Group: Adult

Age: 18 Years - 50 Years

Gender: Male

Scope: National

Treatment:
Observational (questionnaire, biospecimen collection)
Participants complete a health questionnaire over 30-45 minutes. Patients also provide saliva and semen samples and undergo collection of blood.

Detailed Eligibility:
INCLUSION CRITERIA:
1. Ages 18 to 50 years old
2. Previously enrolled and randomized on AOST0331 or INT0133 (also known as CCG7921 and POG9351)
3. Osteosarcoma survivors without relapse or a subsequent malignancy other than skin cancer following initial treatment on AOST0331 or INT0133 (also known as CCG7921 and POG9351)
4. Able to speak, read and write in English or Spanish
5. All patients and/or their parents or legal guardians must sign a written informed consent
6. All institutional, Food and Drug Administration (FDA), and National Cancer Institute (NCI) requirements for human studies must be met

Applicable Conditions:

  • Pediatric (Childhood) Cancer
  • Sarcoma
  • Participation Institution:

  • UF Gainesville : Beate Oltman Greer
  • Contact:
    Beate Oltman Greer
    Phone: +1 352-294-8744
    Email: bgreer01@ufl.edu

    More Information: View study listing on ClinicialTrials.gov http://www.clinicaltrials.gov/ct2/show/NCT03206450