Clinical Research Office

The mission of the UF Health Cancer Center Clinical Research Office, or CRO, is to help deliver new and promising cancer treatments that improve the lives of our patients at the UF Health Cancer Center. The CRO provides support to our clinical investigators for the development and implementation of cancer clinical trials — facilitating the conduct of high-quality clinical research while adhering to the highest ethical standards and maintaining compliance with all governing bodies.

The Clinical Research Office is committed to supporting clinical research addressing the complex needs of the catchment area and the patients we serve, with an emphasis on providing access to novel cancer treatments. The office provides comprehensive resources to investigators for the efficient conduct of cancer clinical research with representative inclusion of minorities, women, and individuals across the lifespan.

Currently, the clinical research program consists of the CRO and 11 disease-specific working groups (e.g., thoracic, GI, GU, neuro-oncology, hematologic malignancies). It also supports an experimental therapeutics group for early phase clinical trials as well as a Cancer Control and Population Sciences group. These two groups support trials that may be relevant to patients across several different cancer types.

Associate Director of Clinical Research, UF Health Cancer Center; Medical Director, Clinical Research Office

Paul L Crispen



Paul L Crispen M.D.

Program Director And Clinical Associate Professor


(352) 273-6818

George P Kim



George P Kim MD

Clinical Professor


(352) 273-7832

clinical research office


The Clinical Research Office provides a range of services to the clinical investigators at the UF Health Cancer Center.

A researcher works in a lab

clinical research office

Search for a Trial

View open clinical trials.


clinical research office

Investigator-Initiated Trial (IIT) Think Tank

The UF Health Cancer Center IIT Think Tank (I2T3) is a dedicated monthly forum for investigators to refine, discuss, collaborate and collect feedback on new investigator-initiated concepts. 

clinical research office

Disease Site Groups

Each group is charged with developing and maintaining a portfolio of trials that brings forward scientific hypotheses developed in the Research Programs and is relevant to our catchment area.

clinical research office

Scientific Review and Monitoring Committee

The Scientific Review and Monitoring Committee provides critical review of scientific merit, methodology and validity of statistical analyses of cancer-relevant studies prior to activation.


Academic Research Consortium

The Academic Research Consortium Network consists of eight affiliate sites across Florida specializing in all cancer types and trials, under the leadership of the University of Florida Health Cancer Canter.


Project Management Office

The University of Florida Health Cancer Center Project Management Office provides a variety of services to support and promote successful investigator initiated trials for Cancer Center members, from concept development to final result dissemination.

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Clinical Research Office Compliance Group

Within the Clinical Research Office Compliance Group, auditing and monitoring are conducted by the Clinical Trials Auditing Team, along with education and training needs developed by the education and training specialist.

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