Aim 1: Elucidate Principles of Cancer Immunobiology Relevant to Developing or Improving Immuno-Oncology Therapeutics
- Identify and validate immunotherapeutic targets
- Define mechanisms of immune/stem/tumor cell engagement within the microenvironment
- Develop therapeutic modalities to augment anti-tumor immunity
Aim 2: Define Microbiome Contribution to Cancer Development, Therapeutics and Immunoactivity
- Investigate how microbiome-associated metabolites impact anti-tumor immunity
- Explore how the microbiome modulates carcinogenesis
- Study how microorganisms affect therapeutic response through drug metabolism
Aim 3: Translate Scientific Discoveries into Early-Phase Clinical Trials
Engaging members in all four UF Health Cancer Center programs through:
- Disease group mini-retreats
- Program meetings
- The IIT Think Tank (i2T3)
