Lizi Wu
- Mailing Address:
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CGRC Room 362
2033 Mowry Road
Gainesville FL 32610
- Physical Address:
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PO BOX 103610
Cancer & Genetics Research Complex
2033 MOWRY ROAD
GAINESVILLE FL 326110001
- 2022 Cells
- 2022 Molecular therapy : the journal of the American Society of Gene Therapy
- 2021 eLife
- 2021 Nucleic acids research
- 2021 Signal Transduction and Targeted Therapy
- 2021 JCI insight
- 2021
- 2020 The FASEB's Journal
- 2020 Science advances
- 2019 Oral oncology
- 2018 Oncogene
- 2018 Leukemia Research
- 2018 Journal of the National Cancer Institute
- 2016 The Journal of clinical investigation
- 2016 Cell Reports
- 2016 The Journal of clinical investigation
- 2015 Cancer Letters
- 2015 Bmc Cancer
- 2015 Journal of the National Cancer Institute
- 2015 Oncotarget
- 2014 Oncotarget
- 2014 Leukemia
- 2014 Proceedings of the National Academy of Sciences
- 2013 The Scientific World Journal
- 2013 Stem cells (Dayton, Ohio)
- 2013 Oncogene
- 2013 Molecular biology reports
- 2013 Journal of Biological Chemistry
- 2013 The Journal of biological chemistry
- 2012 Oncogene
- 2012 Biochemical and Biophysical Research Communications
- 2012 Oncologist
- 2012 Blood
- 2011 Proceedings of the National Academy of Sciences of the United States of America
- 2010 Blood
- 2010 Genes & cancer
- 2010 The Journal of clinical investigation
- 2010 Gastroenterology
- 2010 Journal of Biological Chemistry
- 2008 Oncogene
- 2007 The Journal of biological chemistry
- 2007 Blood
- 2006 Genes & development
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2005
Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation.The EMBO journal
- 2004 Seminars in cancer biology
- 2004 Gene
- 2003 The Journal of neuroscience : the official journal of the Society for Neuroscience
- 2003 Nature genetics
- 2002 Molecular and cellular biology
- 2001 The Journal of biological chemistry
- 2000 Journal of cell science
- 2000 Nature genetics
- 1999 Biology of reproduction
- 1998 Biology of reproduction
- 1998 Molecular human reproduction
- 1998 Journal of assisted reproduction and genetics
- 1996 Immunogenetics
- 1995 Mammalian genome : official journal of the International Mammalian Genome Society
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Apr 2023
ACTIVE
Elucidating and targeting INSL4 signaling in lung cancerFL DEPT OF HLTH BANKHEAD-COLEY CANCER RE · Principal Investigator
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Aug 2022
ACTIVE
Embedded Printing of Human Respiratory Model with Air-Liquid Interface for COVID-19 ResearchNATL INST OF HLTH NHLBI · Co-Investigator
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Apr 2021
ACTIVE
Team-based Interdisciplinary Cancer Research Training ProgramNATL INST OF HLTH NCI · Co-Investigator
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Aug 2020
ACTIVE
Signaling and Targeting of CRTC1-MAML2 Fusion Oncoprotein in Salivary GlandNATL INST OF HLTH NIDCR · Principal Investigator
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Feb 2019
ACTIVE
Aberrant CRTC activation as a unique vulnerability of lung cancer with LKB1 inactivationNATL INST OF HLTH NCI · Principal Investigator
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Sep 2018
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Aug 2021
OR-DRPD-ROF2018: Identification of the first extracellular nicotinamide adenine dinucleotide-binding receptor in animal cellsUF RESEARCH · Co-Investigator
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Apr 2015
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Mar 2018
A novel noncoding RNA and human lung cancers with inactivated LKB1 signalingNATL INST OF HLTH NCI · Principal Investigator
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Jan 2015
ACTIVE
UF Health Cancer Center Bridge Seed Grant funded through the Florida Consortium of National Cancer Institute Centers ProgramUF HEALTH SHANDS HOSPITAL · Project Manager
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Aug 2014
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May 2020
Signaling and targeting of CRTC1-MAML2 fusion oncoprotein in salivary gland tumorNATL INST OF HLTH · Principal Investigator
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Feb 2012
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Mar 2018
Sponholtz Family Cancer Research Fund – #F14006UF FOUNDATION · Project Manager
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Mar 2006
ACTIVE
Davis Cancer Researach EquipmentUF FOUNDATION · Project Manager
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Issued
September 2019
LncRNA Serves as a Biomarker and Therapeutic Target#10,415,095
Rolf Renne
- Mailing Address:
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PO BOX 103610
GAINESVILLE FL 326110001
- Physical Address:
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1200 NEWELL DR RM R4 295
ACADEMIC RESEARCH BLDG
GAINESVILLE FL 32610
Rolf Renne, Ph.D., is a Professor in the Department of Molecular Genetics and Microbiology, and has studiesd different aspects of Kaposi’s sarcoma-associated herpesvirus (KSHV) since 1995. His current focus is on epigenetic regulation of viral latency and the role of long and small non-coding RNAs in viral biology. His laboratory is using genomics, genetics, and ribonomics approaches to study how viral-encoded genes and microRNAs contribute to KSHV biology and tumorigenesis.
Dr. Renne received his Master’s (1989) and Ph.D. (1993) degrees from the Albert-Ludwigs University of Freiburg, Germany. He performed most of his Ph.D. thesis work at the University of California Davis with Dr. Paul Luciw in the field of Retrovirology. Next, he joined the laboratory of Dr. Don Ganem, UCSF, where he contributed to early work on establishing tissue culture models for KSHV. In 1999, he joined the faculty at Case Western Reserve University, where he focused on molecular aspects such as DNA binding and DNA replication of the KSHV latency-associated nuclear antigen (LANA) and the establishment of the only available KS xenograft model. In 2004, he moved to the University of Florida, where his laboratory was one of four to identify KSHV-encoded microRNAs. More recently, Dr. Renne has contributed to studies on HSV-1, EBV, HHV-6, MHV-68, and poxviruses. Dr. Renne has been continuously funded by multiple NCI grants since 2004, and in 2017, was awarded a multi-investigator NCI Program project together with Drs. Scott Tibbetts (UF), and Erik Flemington (Tulane University). This P01 Project was successfully renewed in 2022. Dr. Renne is on the editorial board of Journal of Virology, Virology, and serves on multiple NIH special emphasis panels. In 2009, he co-chaired the 11th International Workshop on KSHV and related agents and in 2015 the 40th International Herpesvirus Workshop. The unifying theme of his research projects is to deepen our understanding on how latent gamma-herpesvirus gene products including microRNAs and long noncoding RNAs contribute to viral tumorigenesis. While his focus is on Kaposi’s sarcoma, Primary effusion lymphomas, he also collaborates on EBV-associated cancer, and animal models such as MHV68 and various noninfectious cancers including breast cancer and melanoma. In 2017, he was appointed Associate Director for Basic Science at the UF Health Cancer Center, and in 2019 was named the Henry E. Innes Professor of Cancer Research. In 2021, he was appointed member of the NCI panel A for Cancer Center reviews.
- 2023 Frontiers in oncology
- 2023 Journal of Virology
- 2023 mBio
- 2023 bioRxiv : the preprint server for biology
- 2023 Molecular biology and evolution
- 2023 mSphere
- 2022 Viruses
- 2022 Scientific reports
- 2021 RNA (New York, N.Y.)
- 2021 Cancers
- 2021 PLOS Pathogens
- 2021 Journal of virology
- 2021 Current protocols
- 2021 PLOS Genetics
- 2020 Drug metabolism and disposition: the biological fate of chemicals
- 2020 Cell host & microbe
- 2019 PLOS Pathogens
- 2019 mBio
- 2019 PLoS pathogens
- 2019 Journal of virology
- 2019 Gene therapy
- 2018 Trends in cancer
- 2018 Nucleic acids research
- 2018 Non-coding RNA
- 2018 Journal of virology
- 2018 PLoS pathogens
- 2018 Proceedings of the National Academy of Sciences of the United States of America
- 2017 PLOS Pathogens
- 2016 PLoS pathogens
- 2016 Oncotarget
- 2016 mBio
- 2016 Oncotarget
- 2016 mSphere
- 2016 Viruses
- 2015 PLoS pathogens
- 2015 Journal of virology
- 2015 Journal of virology
- 2015 PLoS pathogens
- 2015 Journal of virology
- 2014 BMC genomics
- 2014 Nucleic acids research
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2014
Helminth Infection Reactivates Latent Gamma-Herpesvirus Via Cytokine Competition At a Viral PromoterScience
- 2014 Critical reviews in eukaryotic gene expression
- 2014 Viruses
- 2014 PLoS pathogens
- 2014 Computational and structural biotechnology journal
- 2014 mBio
- 2014 Oncotarget
- 2013 Current opinion in virology
- 2013 Journal of medical virology
- 2013 Nucleic acids research
- 2013 Journal of virology
- 2012 PLoS pathogens
- 2012 Journal of virology
- 2011 Journal of virology
- 2011 Biochimica et biophysica acta
- 2011 Methods in molecular biology (Clifton, N.J.)
- 2010 Current opinion in microbiology
- 2010 The Journal of general virology
- 2010 PLoS pathogens
- 2010 Journal of virology
- 2010 Genes & development
- 2009 Journal of virology
- 2009 Glia
- 2009 Trends in microbiology
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2008
KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor.Blood
- 2007 Journal of virology
- 2007 The Journal of infectious diseases
- 2007 PLoS pathogens
- 2007 Journal of virology
- 2006 Journal of virology
- 2006 Inhalation toxicology
- 2005 Journal of virology
- 2005 The Journal of biological chemistry
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2005
Characterization of the minimal replicator of Kaposi's sarcoma-associated herpesvirus latent origin.Journal of virology
- 2004 The Journal of biological chemistry
- 2002 The Journal of biological chemistry
- 1980 Journal of environmental pathology and toxicology
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Aug 2022
ACTIVE
Investigating miR-9-5p and its targets as interventional and clinicopathologic predictors of laryngeal cancer racial disparate outcomesUS ARMY MED RES ACQUISITION · Other
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Jun 2022
ACTIVE
Noncoding RNAs in gamma-Herpesvirus Biology and AIDS MalignanciesNATL INST OF HLTH NCI · Principal Investigator
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Jan 2022
ACTIVE
MicroRNA turnover induced by target RNAs in Colorectal CancerAMER CANCER SOC · Co-Investigator
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Jan 2019
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Oct 2020
UFF F006200 Innes ProfessorshipUF FOUNDATION · Principal Investigator
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Sep 2018
ACTIVE
The Role of H3.3 histone variant in the pathogenesis of oral Kaposi's SarcomaNATL INST OF HLTH NIDCR · Principal Investigator
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Feb 2017
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Jan 2022
Noncoding RNAs in gamma-Herpesvirus Biology and AIDS MalignanciesNATL INST OF HLTH NCI · Principal Investigator
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Jul 2015
ACTIVE
Florida Academic Cancer Center Alliance Seed GrantsUF HEALTH SHANDS HOSPITAL · Project Manager
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Feb 2015
ACTIVE
UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers ProgramUF HEALTH SHANDS HOSPITAL · Project Manager
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Jan 2015
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Dec 2020
Role of MHV68 miRNAs in latency and pathogenesisNATL INST OF HLTH NIAID · Co-Investigator
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Jan 2015
ACTIVE
UF Health Cancer Center Bridge Seed Grant funded through the Florida Consortium of National Cancer Institute Centers ProgramUF HEALTH SHANDS HOSPITAL · Project Manager
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Jul 2014
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Jun 2017
Histone variant H3.3 and KSHV LANA in the pathogenesis of oral Kaposis sarcomaNATL INST OF HLTH NIDCR · Principal Investigator
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Aug 2013
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Aug 2016
Identification of KSHV miRNA targets in endothelial cells and characterization miRNA knockout virusesNATL INST OF HLTH · Principal Investigator
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Dec 2012
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Jan 2019
Studying the role of KSHV-encoded miRNAsNATL INST OF HLTH NCI · Principal Investigator
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Mar 2011
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Feb 2017
LANA and Cellular Gene ExpressionNATL INST OF HLTH NCI · Principal Investigator
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Mar 2006
ACTIVE
Davis Cancer Researach EquipmentUF FOUNDATION · Project Manager
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1989-1993
PhD, Retrovirology/Foamy VirusesAlbert-Ludwigs University
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1984-1989
MS, BiologyAlbert-Ludwigs University