Mechanisms of Oncogenesis

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Program Meeting

Fourth Monday of every two months | 12-1 p.m. | Online via Zoom ResearchDevelopment@cancer.ufl.edu

Mission

The mission of the Mechanisms of Oncogenesis (MOO) program at the University of Florida Health Cancer Center is to understand how normal cells undergo complex changes leading to cancer.

A man in a white coat works at a laboratory bench.

The scientific objectives of the MOO program are to elucidate the deregulated genetic and epigenetic events that drive tumor initiation and progression and develop new cancer targeting strategies.

The research aims focus on identifying and characterizing genetic and epigenetic alterations, elucidating the role of noncoding RNAs in cancer, studying oncogenic mechanisms of DNA tumor viruses, and translating MOO discovery to novel therapeutic approaches.

Aims

The aims of the MOO program are to elucidate the role of genetic and epigenetic alterations in cancer; define the role of regulatory microRNAs and long noncoding RNAs in oncogenesis; and translate MOO discoveries into novel therapeutic approaches.

Program Members

To request an update, please email ResearchDevelopment@cancer.ufl.edu.

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Rhonda Bacher

Rhonda Bacher, PHD

Associate Professor

Department of Biostatistics, College of Public Health and Health Professions

Program: MOO

Research Interests:

  • Bioinformatics, Biostatistics

Charles Baer

Charles Baer, BS,MA,PHD

Professor

Department of Biology, College of Liberal Arts and Sciences

Program: MOO

Research Interests:

  • Evolutionary Biology, Population Genetics, Quantitative Genetics

Richard L Bennett

Richard L Bennett, BA,PHD

Research Associate Professor

Department of Medicine, College of Medicine

Program: MOO

Research Interests:

  • Apoptosis & Cell Death Pathways, Cancer Genetics, Cell Signaling Pathways, Epigenetics, Hematologic Malignancies, Immunoregulation & Suppression, Leukemia, Lymphoma, Post-Transcriptional Gene Regulation, RNA Processing, Virology/Virus-Host Interactions

Sumita Bhaduri-Mcintosh

Sumita Bhaduri-Mcintosh, MD,PHD

Professor

Department of Pediatrics, College of Medicine

Program: MOO

Research Interests:

  • Cancer Genetics, Cell Signaling Pathways, DNA Damage & Repair, DNA Replication, Epigenetics, Hematologic Malignancies, Virology/Virus-Host Interactions

David C Bloom

David C Bloom, BS,PHD

Professor

Department of Molecular Genetics and Microbiology, College of Medicine

Program: MOO

Research Interests:

  • Epigenetics, Oncolytic Viral Vectors, Virology/Virus-Host Interactions

Jason Orr Brant

Jason Orr Brant, BS,PHD

Research Assistant Professor

Department of Biostatistics, College of Public Health and Health Professions

Program: MOO

Research Interests:

  • Bioinformatics, Epigenetics

Jorg Bungert

Jorg Bungert, BS,PHD

Professor

Department of Biochemistry and Molecular Biology, College of Medicine

Program: MOO

Research Interests:

  • Epigenetics, Hematologic Malignancies

Jason M Butler

Jason M Butler, PHD

Professor

Department of Medicine, College of Medicine

Program: MOO

Research Interests:

  • Angiogenesis, Cell Signaling Pathways, Chemotherapy, DNA Damage & Repair, Hematologic Malignancies, Stem Cells, Vascular Targeting

Melike Caglayan

Melike Caglayan, BS,MS,PHD

Assistant Professor

Department of Biochemistry and Molecular Biology, College of Medicine

Program: MOO

Research Interests:

  • Chemotherapy, DNA Damage & Repair, DNA Replication, Drug Design

Li Chen

Li Chen, PHD

Associate Professor

Department of Biostatistics, College of Public Health and Health Professions

Program: MOO

Research Interests:

  • Bioinformatics, Biostatistics, Cancer Communications, Cancer Genetics, Epigenetics
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