August Publications » Cancer Institute » UF Health Cancer Institute

Recent publications from the UF Health Cancer Institute.

Cancer Control and Population Sciences

Bryan E, Lunsford K, Bagautdinova D, Reese S, Mailhot Vega RB, Bylund CL, Sae-Hau M, Weiss ES, Lagmay JP, Fisher CL. Enhancing school- and work-related supportive care in adolescent and young adult (AYA) oncology: A qualitative study merging AYA, parent, and clinician perspectives. J Psychosoc Oncol. 2026 Aug 6:1-16. doi: 10.1080/07347332.2026.2708225. Online ahead of print. PubMed PMID: 42560846.

Landon S, Hall JM, Yoon SL. Systemic Inflammatory Biomarkers and Cancer-Associated Cachexia: A Narrative Review. Curr Oncol. 2026 Aug 15;33(8):483. doi: 10.3390/curroncol33080483. PubMed PMID: 42645388; PubMed Central PMCID: PMC13511127.

Mobley EM, Doody DR, Colan SD, Aggarwal S, Aplenc R, Armenian SH, Baker KS, Bhatia S, Constine LS, Freyer DR, Kopp LM, Leisenring WM, Sasaki N, Vrooman LM, Asselin BL, Schwartz CL, Chow EJ, Lipshultz SE. Longitudinal Change in Cardiac Function After Doxorubicin and Dexrazoxane: A Report From Children’s Oncology Group ALTE11C2. J Clin Oncol. 2026 Aug 6:JCO2600260. doi: 10.1200/JCO-26-00260. Online ahead of print. PubMed PMID: 42561216.

Lynch EJ, Carpenter LT, Corona KN, Fatimilehin AO, Seligson ND. Relacorilant in Combination With Nab-Paclitaxel for the Treatment of Adults With Platinum-Resistant Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer. Ann Pharmacother. 2026 Aug 27:10600280261477395. doi: 10.1177/10600280261477395. Online ahead of print. PubMed PMID: 42661432.

Ramos DOS, Moreira SV, Silva MAMD, Fagundes MDC, Faria LL, Paulo TGODA, Torri GB, Altmayer SPL, Hochhegger B. Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis. J Thorac Imaging. 2026 Aug 3. doi: 10.1097/RTI.0000000000000902. Online ahead of print. PubMed PMID: 42543806.

Arthur P, Boamah Mensah AB, Boamah Mensah K, Konney TO, Amuasi J, Kulasingam S, Virnig BA. Gatekeepers or barriers? Exploring traditional medicine practitioners’ understanding of breast cancer in Ghana. PLoS One. 2026 Aug 5;21(8):e0355289. doi: 10.1371/journal.pone.0355289. eCollection 2026. PubMed PMID: 42555607; PubMed Central PMCID: PMC13440859.

Hochhegger B, Zhang JMF, da Fonseca JM, Bergmann L, Biederer J, Altmayer S, Hochhegger D, Ackman JB. Evolving Indications, Technical Quality, Diagnostic Outcomes, and Utilization Patterns of Chest Magnetic Resonance Imaging: A Quaternary Care Center Experience With 3730 Patients Over 25 Years. J Thorac Imaging. 2026 Aug 4. doi: 10.1097/RTI.0000000000000899. Online ahead of print. PubMed PMID: 42548163.

Dowllah IM, Nguyen BL, Jacintho Moritz CE, Babuschak J, Smuder AJ. Effects of mitochondrial ABCB7 transporter upregulation on acute doxorubicin cardiorespiratory muscle injury. J Appl Physiol (1985). 2026 Aug 1;141(2):435-447. doi: 10.1152/japplphysiol.00326.2025. Epub 2026 Jul 13. PubMed PMID: 42441500; PubMed Central PMCID: PMC13492732.

Nahid NA, Soliman AI, Baye JF, Petry NJ, Gray CF, Myers RA, Elwood EN, Harris EC, Chakraborty H, Volpi S, Rider R, Dexter PR, Peterson JF, Skaar TC, Parvataneni HK, Cavallari LH, Johnson JA; IGNITE Pragmatic Trial Network Investigators. Tramadol Co-Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control. Clin Pharmacol Ther. 2026 Aug 17:10.1002/cpt.70434. doi: 10.1002/cpt.70434. Online ahead of print. PubMed PMID: 42605662; PubMed Central PMCID: PMC13478926.

Pyakurel U, Zhang Y, Sabounchi R, Bayat F, Hu J, Brousmiche S, Bryant C, Mendenhall N, Johnson P, Altunbas C. Improvement of soft tissue contrast and CT number accuracy in proton therapy CBCT with hardware-based scatter suppression: results from a prospective trial. Int J Radiat Oncol Biol Phys. 2026 Aug 18:S0360-3016(26)04203-3. doi: 10.1016/j.ijrobp.2026.08.025. Online ahead of print. PubMed PMID: 42612829.

Yasinzai AQK, McKean JA, Thompson GR, Paniccia A, Parrish AM, Underwood PW, Gim G, Hughes SJ, George TJ, Nassour I. Pancreatoblastoma: A Descriptive and Comparative Analysis with Pancreatic Ductal Adenocarcinoma Using SEER Data. Cancers (Basel). 2026 Aug 16;18(16):2642. doi: 10.3390/cancers18162642. PubMed PMID: 42649954; PubMed Central PMCID: PMC13510784.

Altmayer S, Guo HH, Lin M, Vigneault DM, You H, Patel P, Shaller B, Chang J, Free D, Yenepalli A, Choi HJ, Hochhegger B, Leung AN. Nondiagnostic Lung Biopsies: Radiologist Performance in Prediction of Malignancy. Acad Radiol. 2026 Aug 26:S1076-6332(26)00586-6. doi: 10.1016/j.acra.2026.07.078. Online ahead of print. PubMed PMID: 42648924.

Manrique AF, Tadese BK, Huang Y, Rohlwing K, Lou X, Li A, Tota JE, Saraiya M, Guo Y, Wang WV. Real-World Effectiveness and Impact of Human Papillomavirus Vaccination in Males: A Comprehensive Review. Int J Infect Dis. 2026 Aug 20:109052. doi: 10.1016/j.ijid.2026.109052. Online ahead of print. PubMed PMID: 42624282.

Boamah Mensah AB, Mensah KB, Agbeko AE, Mohammed A, Okyere J, Dodd C, Horvath K, Virnig B, Clegg-Lamptey JN, Kulasingam S. Informing mobile health strategies: Study of mobile phone ownership among rural women for breast cancer control in Ghana. Digit Health. 2026 Aug 3;12:20552076261476178. doi: 10.1177/20552076261476178. eCollection 2026 Jan-Dec. PubMed PMID: 42558772; PubMed Central PMCID: PMC13438229.

Bitsie KR, Pearson TA, Kwan ML, Yaghjyan L, Scarton L, Shariff-Marco S, Andraos TY, D’Addario LL, Kushi LH, Cheng TD. Self-reported racial and ethnic discrimination in patient-provider interactions and the initiation of adjuvant therapies for breast cancer in the pathways study. Breast Cancer Res Treat. 2026 Aug 10;218(3):36. doi: 10.1007/s10549-026-08037-w. PubMed PMID: 42573830; PubMed Central PMCID: PMC13457354.

Khalid S, Ratzki-Leewing A, Brito JP, Ospina NS, McCoy RG. Variation and potential overuse in thyroid ultrasound ordering: exploratory insights from a clinician survey. Endocrine. 2026 Aug 21;91(1):283. doi: 10.1007/s12020-026-04742-0. PubMed PMID: 42627557; PubMed Central PMCID: PMC13498611.

Shin B, Kim S, Kim H, Choi C, Yeom YS, Griffin KT, Sato T, Bolch WE, Jokisch DW, Kim CH. Fetal specific absorbed fractions of ICRP pregnant-female mesh phantoms: methodology and dosimetric trends. Phys Med Biol. 2026 Aug 20;71(16). doi: 10.1088/1361-6560/ae97ae. PubMed PMID: 42575152.

Smither WW, Choi C, Shin B, Jokisch DW, Mate-Kole EM, Dewji SA, Bolch WE. Photon specific absorbed fractions for the ICRP family of mesh-type reference computational phantoms. Phys Med Biol. 2026 Aug 24;71(16):165023. doi: 10.1088/1361-6560/ae94db. PubMed PMID: 42551490; PubMed Central PMCID: PMC13501261.

Adam DP, Yusufaly T, Marsh IR, Bastiaannet R, Kiess A, Bolch WE, Zaid N, Chhabra A, K R, Gabrielson K, Brayton C, Sgouros G, Hobbs RF. Parameterizable salivary gland model for small-scale Monte Carlo radiopharmaceutical therapy dosimetry: evaluation of mouse and human model. Phys Med Biol. 2026 Aug 6. doi: 10.1088/1361-6560/ae9686. Online ahead of print. PubMed PMID: 42562002.

Tefera M, Letta S, LeLaurin JH, Mkuu R, Wilfong T, Tolera A, Montague M, Bteddini D, Nakkash R, Mariam DH, Salloum RG. Stakeholder Perspectives on Community Tobacco Use and the Implementation of Tobacco Use Treatment in Eastern Ethiopia: A Qualitative Study. Nicotine Tob Res. 2026 Aug 22:ntag144. doi: 10.1093/ntr/ntag144. Online ahead of print. PubMed PMID: 42631705.

Bteddini DS, El Ashkar C, Abla R, Montague M, El Kadi L, Kabakian-Khasholian T, Lee JH, Theis R, Khaywa J, Li D, Hamadeh RS, Ward K, Osman MH, Shelley DR, Romani M, Nakkash R, Salloum RG, LeLaurin JH. Adapting multicomponent tobacco use treatment strategies for implementation in the Lebanese primary healthcare system: a mixed-methods study. BMJ Open. 2026 Aug 31;16(8):e120118. doi: 10.1136/bmjopen-2026-120118. PubMed PMID: 42674794.

Hubley J, Yoon SL, Grundmann O. A Comparative Pilot Survey of Kratom Utilization by Cancer and Non-Cancer Consumers. J Palliat Med. 2026 Aug 26:10966218261484371. doi: 10.1177/10966218261484371. Online ahead of print. PubMed PMID: 42655877.

Russo S, Wee C, Jean-Baptiste S, Kirschner AN, Koneru B, Kluwe C, Ling DC, Newman N, Pearlstein K, Sharifzadeh Y, Tendulkar R, Dove A. The Role of Adjuvant Radiotherapy for the Prevention of Recurrent Hypertrophic Scars/Keloids: An American Radium Society (ARS) Appropriate Use Criteria (AUC). Am J Clin Oncol. 2026 Aug 28. doi: 10.1097/COC.0000000000001366. Online ahead of print. PubMed PMID: 42671560. M

Mazirka P, Ghandour Z, Terracina KP, Goldstein LE, Nordenstam J, Read TE. Sigmoid Adenocarcinoma Occurring 72 Years After Ureterosigmoidostomy: Implications for Lifelong Surveillance. Am Surg. 2026 Aug 23:31348261480831. doi: 10.1177/00031348261480831. Online ahead of print. PubMed PMID: 42634452.

Ebadi M, Duarte EM, Hajarat T, Leon ME. An Unusual Low-Grade Biphasic Pulmonary Neoplasm Harboring BRAF-V600E Mutation: A Potential Variant of Bronchiolar Adenoma. Int J Surg Pathol. 2026 Aug 13:10668969261462161. doi: 10.1177/10668969261462161. Online ahead of print. PubMed PMID: 42595357.

Cancer Targeting and Therapeutics

Mi K, Chen Q, Yuan L, He C, Monteiro-Riviere NA, Riviere JE, Lin Z. Analysis of Pharmacokinetic-Pharmacodynamic Relationships of Nanoparticles against Tumors. ACS Nano. 2026 Aug 18;20(32):22485-22504. doi: 10.1021/acsnano.6c02730. PubMed PMID: 42611221; PubMed Central PMCID: PMC13488496.

Merugu S, Mi K, Chen Q, Monteiro-Riviere NA, Riviere JE, Lin Z. Are similar nanoforms comparable in biodistribution? Data-driven approaches for optimizing nanomedicine design. Mater Today Nano. 2026 Aug;35:100891. doi: 10.1016/j.mtnano.2026.100891. Epub 2026 Jul 22. PubMed PMID: 42529650; PubMed Central PMCID: PMC13418285. D

aneshvar K, Karkheiran K, Ghochani G, Mirzaei A, Ebrahimiadib N. Iris lesions: A review. Surv Ophthalmol. 2026 Aug 18:S0039-6257(26)00122-0. doi: 10.1016/j.survophthal.2026.08.009. Online ahead of print. PubMed PMID: 42612753.

Xu Z, Jolly KJ, Zhang F. Leveraging endogenous proteins to improve cancer nanomedicine delivery. Nanoscale. 2026 Aug 11. doi: 10.1039/d6nr01492e. Online ahead of print. PubMed PMID: 42576815; PubMed Central PMCID: PMC13458888.

Huang D, Zhang M, Stansfield BN, Ahmed M, Xu T, Alexander L, Anandhan A, Ma M, Liu P, Yang-Hartwich Y, Fang D, Chapman E, Garcia JGN, Wong PK, Ooi A, Zhang DD. NRF2-mediated ferroptosis suppression defines a cancer-specific vulnerability in tumors. Redox Biol. 2026 Aug 19;96:104352. doi: 10.1016/j.redox.2026.104352. Online ahead of print. PubMed PMID: 42623935; PubMed Central PMCID: PMC13524513.

Shi P, Melillo B, McHenry MW, Camara CM, Yang K, Njomen E, Godes M, Pazyra-Murphy MF, Branch MR, Tesar B, Segal RA, Rubin LL, Cameron MD, Bird GH, Wales TE, Gygi SP, Cravatt BF, Walensky LD. An enantioselective covalent inhibitor of BAX confers cytoprotection in vivo. Nat Chem Biol. 2026 Aug 28. doi: 10.1038/s41589-026-02297-9. Online ahead of print. PubMed PMID: 42665659.

Mack ZT, Yastrebova M, Lim CU, Ding X, Li J, Khamidullina A, Sharko AC, Saint-Antoine M, Hilimire TA, Schools GP, Digsby K, Eckstrom A, Belcher E, Madiot G, Ji H, Sikirzhitski V, Cai C, Cai G, Singh A, Tatarskiy V, Chen M, Roninson IB, Broude EV. CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo. Cell Rep Med. 2026 Aug 19:103004. doi: 10.1016/j.xcrm.2026.103004. Online ahead of print. PubMed PMID: 42617601.

Pyakurel U, Zhang Y, Sabounchi R, Bayat F, Hu J, Brousmiche S, Bryant C, Mendenhall N, Johnson P, Altunbas C. Improvement of soft tissue contrast and CT number accuracy in proton therapy CBCT with hardware-based scatter suppression: results from a prospective trial. Int J Radiat Oncol Biol Phys. 2026 Aug 18:S0360-3016(26)04203-3. doi: 10.1016/j.ijrobp.2026.08.025. Online ahead of print. PubMed PMID: 42612829.

Palaz F, Yu X, Bruner J, Feely M, Cai G, Duarte S, Zarrinpar A. Independent Multi-Cohort RNA-Seq Analysis Does Not Support Recurrent DNAJB1::PRKACA Fusion in Hepatoblastoma or Biliary Atresia. Comment on Fleifil et al. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers 2025, 17, 83. Cancers (Basel). 2026 Aug 19;18(16):2681. doi: 10.3390/cancers18162681. PubMed PMID: 42649992; PubMed Central PMCID: PMC13511131.

Nguyen TB, Stitgen AM, Tamura AM, Sumerlin BS, Haynes CL. Boronic acid-based sensors: from fundamental chemistry to optimized biosensing platforms. Chem Commun (Camb). 2026 Aug 19. doi: 10.1039/d6cc04030f. Online ahead of print. PubMed PMID: 42615323.

Le Reun E, Meijers A, Romero-Exposito MT, Kotov I, Indelicato DJ, Weber DC. Radiation-induced tumor following pencil beam scanning proton therapy for pediatric intracranial ependymoma: a pragmatic analysis of risk factors. J Radiat Res. 2026 Aug 20:rrag066. doi: 10.1093/jrr/rrag066. Online ahead of print. PubMed PMID: 42623509.

Bryan E, Lunsford K, Bagautdinova D, Reese S, Mailhot Vega RB, Bylund CL, Sae-Hau M, Weiss ES, Lagmay JP, Fisher CL. Enhancing school- and work-related supportive care in adolescent and young adult (AYA) oncology: A qualitative study merging AYA, parent, and clinician perspectives. J Psychosoc Oncol. 2026 Aug 6:1-16. doi: 10.1080/07347332.2026.2708225. Online ahead of print. PubMed PMID: 42560846.

Immuno-Oncology and Microenvironment

Lightsey S, Consalvo V, Ali SR, Valdes DP, Oyer JL, Gloger G, Copik AJ, Rinaldi-Ramos C, Sharma B. Towards reliable tracking of natural killer cells using commercial iron oxide nanoparticles and magnetic particle imaging. Biomater Sci. 2026 Aug 31. doi: 10.1039/d6bm00655h. Online ahead of print. PubMed PMID: 42669426.

Jin D, DiVita B, Reid A, Love C, Figg JW, Francis C, Falceto Font L, Long-James K, Hilferty D, Stansbury S, Morikawa N, Sebastian M, Boulant S, Mitchell DA, Flores C. Dendritic Cell Dysfunction Underlies Immune Escape After Adoptive Cellular Therapy in Glioblastoma. Cancers (Basel). 2026 Aug 18;18(16):2669. doi: 10.3390/cancers18162669. PubMed PMID: 42649980; PubMed Central PMCID: PMC13510367.

Chuck J, Parsons JV, Solt LA. A microbial PPARadigm for gut protection. Nat Microbiol. 2026 Aug;11(8):2084-2085. doi: 10.1038/s41564-026-02423-2. No abstract available. PubMed PMID: 42533068.

Temples MN, Lightsey S, Conklin T, Newport RS, Phelps EA, Sharma B. 3D chemotaxis chip for investigating natural killer cell migration mechanisms. Front Immunol. 2026 Aug 13;17:1762203. doi: 10.3389/fimmu.2026.1762203. eCollection 2026. PubMed PMID: 42661925; PubMed Central PMCID: PMC13518586.

Shaffer BC, Al Malki MM, Jimenez AMJ, Stanek J, Bo-Subait S, Logan BR, Kou J, Leckrone E, Stefanski HE, Spellman SR, Malmberg C, Askar M, Cusatis R, Modi D, Khimani F, Hamadani M, Maiers M, Cook R, Ballen K, Bolanos-Meade J, Rao U, Milner J, Abboud R, Jamieson K, Carrum G, Dholaria B, Hogan WJ, Reshef R, Kosuri S, Loren A, Larkin K, Arai S, Qayed M, Choi SW, Broglie L, Auletta JJ, Shaw BE, Devine SM, Gooptu M. Phase II Study of Posttransplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis After HLA-Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort. Am J Hematol. 2026 Aug 31. doi: 10.1002/ajh.70489. Online ahead of print. PubMed PMID: 42674730.

Baxter JS, Montiel Equihua C, Molenaar JJ, Berlanga P, Bishop MW, Blanc P, Campbell-Hewson Q, Casanova M, Cortes-Ciriano I, Crompton B, Daems S, Danielson L, Dela Cruz F, Flanagan A, Gorlick R, Graham A, Guenther LM, Hecker-Nolting S, Helman L, Kavanagh-Williamson M, Kearns P, Lass G, Ip-Toma C, Ligon J, Lewin J, Livingston JA, Marchais A, McCabe MG, Mittnacht S, Nathrath M, Palmerini E, Pantziarka P, Patel S, Patel S, Reed D, Roberts R, Scotlandi K, Slotkin E, Tseng M, Smallwood W, Sorensen PH, Valverde C, Wane M, Wilson GA, Pearson ADJ, Jenkinson D, Gaspar N, Strauss SJ; LifeArc; Innovative Therapies for Children and Adolescents with Cancer (ITCC); Cancer Research UK; Cancer Grand Challenge Protect team. Paediatric therapeutic development workshop on osteosarcoma. Br J Cancer. 2026 Aug 18. doi: 10.1038/s41416-026-03572-1. Online ahead of print. PubMed PMID: 42613365.

Jimenez Jimenez AM, Stanek J, Logan BR, Leckrone E, Stefanski HE, Auletta JJ, Spellman SR, Malmberg C, Askar M, Cusatis RN, Shaffer BC, Modi D, Khimani F, Gooptu M, Hamadani M, Maiers M, Bo-Subait S, Bolanos-Meade J, Rao U, Milner J, Abboud R, Jamieson KJ, Carrum G, Dholaria B, Hogan WJ, Reshef R, Kosuri S, Cook RJ, Ballen K, Loren AW, Larkin K, Arai S, Qayed M, Choi SW, Broglie L, Shaw BE, Devine SM, Al Malki MM. Outcomes after 7/8 and <7/8 mismatched unrelated donor PBSC transplantation with PTCy: results from the ACCESS trial. Blood Adv. 2026 Aug 19:bloodadvances.2026021081. doi: 10.1182/bloodadvances.2026021081. Online ahead of print. PubMed PMID: 42616616.

Mechanisms of Oncogenesis

Huang D, Zhang M, Stansfield BN, Ahmed M, Xu T, Alexander L, Anandhan A, Ma M, Liu P, Yang-Hartwich Y, Fang D, Chapman E, Garcia JGN, Wong PK, Ooi A, Zhang DD. NRF2-mediated ferroptosis suppression defines a cancer-specific vulnerability in tumors. Redox Biol. 2026 Aug 19;96:104352. doi: 10.1016/j.redox.2026.104352. Online ahead of print. PubMed PMID: 42623935; PubMed Central PMCID: PMC13524513.

Akinyemi IA, Zeigler TM, Willman GH, Patel D, El-Guindy A, McIntosh MT, Bhaduri-McIntosh S. Clinical-Stage Nanatinostat Triggers Productive Epstein-Barr Virus Lytic Replication. J Med Virol. 2026 Aug;98(8):e71077. doi: 10.1002/jmv.71077. PubMed PMID: 42517423; PubMed Central PMCID: PMC13410831.

Nolte N, Petek M, Angulo Lara P, Mulroney L, Nicassio F, Marroni F, McIntyre L. The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance. NAR Genom Bioinform. 2026 Aug 4;8(3):lqag071. doi: 10.1093/nargab/lqag071. eCollection 2026 Sep. PubMed PMID: 42553517; PubMed Central PMCID: PMC13434171.